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  1. Article

    Open Access

    Long-term prognosis after kidney donation: a propensity score matched comparison of living donors and non-donors from two population cohorts

    Live donor nephrectomy is a safe procedure. However, long-term donor prognosis is debated, necessitating high-quality studies.

    Shiromani Janki, Abbas Dehghan in European Journal of Epidemiology (2020)

  2. Article

    Open Access

    Neutrophil gelatinase-associated lipocalin (NGAL) predicts the occurrence of malaria-induced acute kidney injury

    Acute kidney injury (AKI) is a frequently encountered complication of imported Plasmodium falciparum infection. Markers of structural kidney damage have been found to detect AKI earlier than serum creatinine-base...

    Marlies E. van Wolfswinkel, Liese C. Koopmans, Dennis A. Hesselink in Malaria Journal (2016)

  3. Article

    Open Access

    Acute kidney injury in imported Plasmodium falciparum malaria

    Acute kidney injury (AKI) is a known complication of malaria, and is reported to occur in up to 40 % of adult patients with a severe Plasmodium falciparum infection in endemic regions. To gain insight in the inci...

    Liese C. Koopmans, Marlies E. van Wolfswinkel, Dennis A. Hesselink in Malaria Journal (2015)

  4. Article

    Open Access

    Hyponatraemia in imported malaria: the pathophysiological role of vasopressin

    In the pathophysiology of hyponatraemia in malaria, the relative contribution of appropriate and inappropriate arginine vasopressin (AVP) release is unknown; the trigger for inappropriate AVP release is also u...

    Ewout J Hoorn, Marlies E van Wolfswinkel, Dennis A Hesselink in Malaria Journal (2012)

  5. Article

    Open Access

    Copeptin does not accurately predict disease severity in imported malaria

    Copeptin has recently been identified to be a stable surrogate marker for the unstable hormone arginine vasopressin (AVP). Copeptin has been shown to correlate with disease severity in leptospirosis and bacter...

    Marlies E van Wolfswinkel, Dennis A Hesselink, Ewout J Hoorn in Malaria Journal (2012)

  6. No Access

    Article

    The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension

    Calcineurin inhibitors, such as tacrolimus, are widely used immunosuppressive agents, but they can cause hypertension. In studies of tacrolimus-treated mice, the authors show that hypertension is due to activa...

    Ewout J Hoorn, Stephen B Walsh, James A McCormick, Antje Fürstenberg in Nature Medicine (2011)

  7. Article

    Open Access

    Hyponatraemia in imported malaria is common and associated with disease severity

    Hyponatraemia (serum sodium < 135 mmol/L) has long been recognized as a complication of malaria. However, few studies have been done in non-immune adult populations. It has not been investigated previously how...

    Marlies E van Wolfswinkel, Dennis A Hesselink, Robert Zietse in Malaria Journal (2010)