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Article
Open AccessLong-term prognosis after kidney donation: a propensity score matched comparison of living donors and non-donors from two population cohorts
Live donor nephrectomy is a safe procedure. However, long-term donor prognosis is debated, necessitating high-quality studies.
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Article
Open AccessNeutrophil gelatinase-associated lipocalin (NGAL) predicts the occurrence of malaria-induced acute kidney injury
Acute kidney injury (AKI) is a frequently encountered complication of imported Plasmodium falciparum infection. Markers of structural kidney damage have been found to detect AKI earlier than serum creatinine-base...
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Article
Open AccessAcute kidney injury in imported Plasmodium falciparum malaria
Acute kidney injury (AKI) is a known complication of malaria, and is reported to occur in up to 40 % of adult patients with a severe Plasmodium falciparum infection in endemic regions. To gain insight in the inci...
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Article
Open AccessHyponatraemia in imported malaria: the pathophysiological role of vasopressin
In the pathophysiology of hyponatraemia in malaria, the relative contribution of appropriate and inappropriate arginine vasopressin (AVP) release is unknown; the trigger for inappropriate AVP release is also u...
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Article
Open AccessCopeptin does not accurately predict disease severity in imported malaria
Copeptin has recently been identified to be a stable surrogate marker for the unstable hormone arginine vasopressin (AVP). Copeptin has been shown to correlate with disease severity in leptospirosis and bacter...
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Article
The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension
Calcineurin inhibitors, such as tacrolimus, are widely used immunosuppressive agents, but they can cause hypertension. In studies of tacrolimus-treated mice, the authors show that hypertension is due to activa...
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Article
Open AccessHyponatraemia in imported malaria is common and associated with disease severity
Hyponatraemia (serum sodium < 135 mmol/L) has long been recognized as a complication of malaria. However, few studies have been done in non-immune adult populations. It has not been investigated previously how...