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    Article

    A normative chart for cognitive development in a genetically selected population

    Certain pathogenic genetic variants impact neurodevelopment and cause deviations from typical cognitive trajectories. Understanding variant-specific cognitive trajectories is clinically important for informed ...

    Ania M. Fiksinski, Carrie E. Bearden, Anne S. Bassett in Neuropsychopharmacology (2022)

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    Article

    Using common genetic variation to examine phenotypic expression and risk prediction in 22q11.2 deletion syndrome

    The 22q11.2 deletion syndrome (22q11DS) is associated with a 20–25% risk of schizophrenia. In a cohort of 962 individuals with 22q11DS, we examined the shared genetic basis between schizophrenia and schizophre...

    Robert W. Davies, Ania M. Fiksinski, Elemi J. Breetvelt in Nature Medicine (2020)

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    Article

    The Dutch Bipolar Offspring Study: Cognitive Development and Psychopathology

    Various aspects of the relationship between cognitive impairment and bipolar disorder are not clear yet. This study examines cognitive and educational functioning prospectively in offspring at familial risk fo...

    Wanda M. Tempelaar, Esther Mesman in Journal of Abnormal Child Psychology (2019)

  4. Article

    Open Access

    Early interventions in risk groups for schizophrenia: what are we waiting for?

    Intervention strategies in adolescents at ultra high-risk (UHR) for psychosis are promising for reducing conversion to overt illness, but have only limited impact on functional outcome. Recent studies suggest ...

    Iris E Sommer, Carrie E Bearden, Edwin van Dellen, Elemi J Breetvelt in npj Schizophrenia (2016)