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  1. Article

    Open Access

    Human brucellosis: recent advances and future challenges

    David O’Callaghan in Infectious Diseases of Poverty (2020)

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  2. Article

    Open Access

    Brucellosis in China: history, progress and challenge

    Brucellosis is a neglected zoonosis. It causes acute febrile illness and a potentially debilitating chronic infection in humans, and livestock infection has substantial socioeconomic impact. Over the past two ...

    Hai Jiang, David O’Callaghan, Jia-Bo Ding in Infectious Diseases of Poverty (2020)

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  3. Article

    Methylnaltrexone for the treatment of opioid-induced constipation and gastrointestinal stasis in intensive care patients. Results from the MOTION trial

    Constipation can be a significant problem in critically unwell patients, associated with detrimental outcomes. Opioids are thought to contribute to the mechanism of bowel dysfunction. We tested if methylnaltre...

    Parind B. Patel, Stephen J. Brett, David O’Callaghan… in Intensive Care Medicine (2020)

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  4. Article

    Open Access

    The Brucella TIR domain containing proteins BtpA and BtpB have a structural WxxxE motif important for protection against microtubule depolymerisation

    The TIR domain-containing proteins BtpA/Btp1/TcpB and BtpB are translocated into host cells by the facultative intracellular bacterial pathogen Brucella. Here, they interfere with Toll like receptor signalling to...

    Christine Felix, Burcu Kaplan Türköz, Sebastien Ranaldi… in Cell Communication and Signaling (2014)

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  5. No Access

    Article

    In vitro and in vivo assessment of silver-coated polypropylene mesh to prevent infection in a rat model

    The purpose of this study is to determine the effect of silver coating of polypropylene implants on infection in hernia surgery.

    Wassim Badiou, Jean-Philippe Lavigne… in International Urogynecology Journal (2011)

  6. No Access

    Article

    The Back-End of a Two-Layer Model for a Federated National Datastore for Academic Research VOs that Integrates EGEE Data Management

    This paper proposes an architecture for the back-end of a federated national datastore for use by academic research communities, developed by the e-INIS (Irish National e-InfraStructure) project, and describes...

    Brian Coghlan, John Walsh, Stephen Childs, Geoff Quigley… in Journal of Grid Computing (2010)

  7. No Access

    Article

    Combined Lumbar Spinal and Thoracic High-Epidural Regional Anesthesia as an Alternative to General Anesthesia for High-Risk Patients Undergoing Gastrointestinal and Colorectal Surgery

    A prospective study was undertaken to review the use of combined lumbar spinal and thoracic high-epidural regional anesthesia in high-risk patients who underwent gastrointestinal/colorectal surgery from 2004 t...

    James Skipworth, Attavar Srilekha, Dimitri Raptis… in World Journal of Surgery (2009)

  8. No Access

    Article

    The evolution of chronic infection strategies in the α-proteobacteria

    The α-subdivision of the Proteobacteria is a very large and diverse group of Gram-negative microorganisms. They show great variability in metabolic capacities and inhabit diverse ecological niches. The authors...

    Jacques Batut, Siv G. E. Andersson, David O'Callaghan in Nature Reviews Microbiology (2004)

  9. No Access

    Article

    Authentication and Authorization Mechanisms for Multi-Domain Grid Environments

    This article discusses the authentication and the authorization aspects of security in grid environments spanning multiple administrative domains. Achievements in these areas are presented using the EU DataGri...

    Linda A. Cornwall, Jens Jensen, David P. Kelsey, Ákos Frohner… in Journal of Grid Computing (2004)

  10. No Access

    Article

    High efficiency transformation of Salmonella typhimurium and Salmonella typhi by electroporation

    Salmonella typhimurium and S. typhi were transformd with high efficiency by electroporation. Transformation efficiencies of up to 1010 transformants per μg of pBR322 were obtained. In contrast to chemical transf...

    David O'Callaghan, Alain Charbit in Molecular and General Genetics MGG (1990)

  11. No Access

    Article

    Oral vaccination

    Gordon Dougan, Duncan Maskell, David O'Callaghan… in Antonie van Leeuwenhoek (1988)