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  1. Article

    A urinary peptide biomarker set predicts worsening of albuminuria in type 2 diabetes mellitus

    Microalbuminuria is considered the first clinical sign of kidney dysfunction and is associated with a poor renal and cardiovascular prognosis in type 2 diabetes. Detection of patients who are prone to develop ...

    S. S. Roscioni, D. de Zeeuw, M. E. Hellemons, H. Mischak, P. Zürbig in Diabetologia (2013)

  2. Article

    Open Access

    High serum potassium levels after losartan can reflect more severe renal disease. Reply to Gonçalves AR, El Nahas AM [letter]

    S. S. Roscioni, Y. Miao, D. de Zeeuw, H. J. Lambers Heerspink in Diabetologia (2011)

  3. Article

    Open Access

    Erratum to: Increased serum potassium affects renal outcomes: a post hoc analysis of the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial

    Y. Miao, D. Dobre, H. J. Lambers Heerspink, B. M. Brenner, M. E. Cooper in Diabetologia (2011)

  4. Article

    Open Access

    Increased serum potassium affects renal outcomes: a post hoc analysis of the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial

    To assess the effect of an angiotensin receptor blocker (ARB) on serum potassium and the effect of a serum potassium change on renal outcomes in patients with type 2 diabetes and nephropathy.

    Y. Miao, D. Dobre, H. J. Lambers Heerspink, B. M. Brenner, M. E. Cooper in Diabetologia (2011)

  5. No Access

    Article

    Renal failure induces telomere shortening in the rat heart

    BackgroundRenal failure aggravates pathological cardiac remodelling induced by myocardial infarction (MI). Cardiac remodelling is associated with telomere shortening, a marker for biological ageing. We investigat...

    L. S. Wong, W. A. Windt, A. J. Roks, R. P. van Dokkum in Netherlands Heart Journal (2009)

  6. Article

    Adverse effects of left ventricular hypertrophy in the reduction of endpoints in NIDDM with the angiotensin II antagonist losartan (RENAAL) study

    We explored the impact of baseline left ventricular hypertrophy (LVH) and losartan treatment on renal and cardiovascular (CV) events in 1,513 patients from the Reduction of Endpoints in NIDDM with the Angioten...

    G. Boner, M. E. Cooper, K. McCarroll, B. M. Brenner, D. de Zeeuw in Diabetologia (2005)

  7. Article

    40th EASD Annual Meeting of the European Association for the Study of Diabetes

    M. Veitenhansl, K. Stegner, F.-X. Hierl, C. Dieterle, H. Feldmeier, B. Gutt in Diabetologia (2004)

  8. No Access

    Article

    Recombinant Semliki Forest virus as a vector system for fast and selective in vivo gene delivery into balloon-injured rat aorta

    Previously, we demonstrated that recombinant Semliki Forest virus (SFV) vector rapidly and selectively transfers genes into cultured vascular smooth muscle cells (VSMC), leaving endothelial cells (EC) unaffect...

    A J M Roks, R H Henning, H Buikema, Y M Pinto, M J J Kraak, R A Tio in Gene Therapy (2002)

  9. Article

    35th Annual Meeting of the European Association for the Study of Diabetes

    A. Melander, J. Olsson, G. Lindberg, A. Salzman, T. Howard, P. Stang in Diabetologia (1999)

  10. No Access

    Article

    Pharmacokinetics and pharmacodynamics of candesartan cilexetil in patients with normal to severely impaired renal function

    Objective: We studied the pharmacokinetics and pharmacodynamics of single and multiple doses of candesartan cilexetil 8 mg per day in hypertensive patients with different degrees of rena...

    H. Buter, G. Y. Navis, A. J. J. Woittiez in European Journal of Clinical Pharmacology (1999)

  11. No Access

    Article

    ACE inhibitors and proteinuria

    This review discusses the clinical consequences of uninary protein loss and the effects of inhibitors of the angiotensin converting enzyme (ACE) on this clinical finding. Proteinuria appears to be an important...

    R. T. Gansevoort, D. de Zeeuw, P. E. de Jong in Pharmacy World and Science (1996)

  12. No Access

    Article

    Abstracts of papers and posters

    R. L. Anthonio, A. T. M. Willemsen, T. Visser, A. van Waarde in Pharmacy World and Science (1994)

  13. No Access

    Article

    Abstracts of papers and posters Meeting on Pharmaceutical Sciences

    Russell C. Coile Jr., K. Wiedhaup, Ilva van Bommel in Pharmacy World and Science (1993)

  14. No Access

    Article

    Abstracts of papers

    P. A. v. d. Wouw, H. H. v. Rooy, R. W. Koster, A. J. Porsius in Pharmaceutisch Weekblad (1985)

  15. No Access

    Article

    Pharmacological zero for electromagnetic renal blood flow measurement

    Measurement of blood flow in chronically instrumented laboratory animals using electromagnetic flow probes depends on a reference “zero flow” value. The latter is usually obtained by mechanical vessel occlusio...

    G. J. Jonker, D. de Zeeuw, R. M. Huisman, G. K. van der Hem in Pflügers Archiv (1985)

  16. No Access

    Article

    Blood pressure response to enalaprilic acid in essential hypertension: Dose-response and effect of pre-treatment with furosemide

    Enalaprilic acid (MK 422), the active metabolite of enalapril, has recently become available for intravenous administration. In order to establish the proper dose for rapid blood pressure reduction, 9 patients...

    G. J. Navis, P. E. de Jong, A. J. M. Donker in European Journal of Clinical Pharmacology (1985)

  17. Article

    Flowering of Xanthium under Long-Day Conditions

    EFFORTS to induce flowering in the short-day plant Xanthium pensylvanicum under long-day conditions have consistently failed up to now. From numerous reports it has been concluded that for flower induction a shor...

    D. DE ZEEUW in Nature (1957)