4 Result(s)
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Article
Cathrin Brisken
Biomedicine, general
Human Genetics
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Article
Open AccessEMBER creates a unified space for independent breast cancer transcriptomic datasets enabling precision oncology
Transcriptomics has revolutionized biomedical research and refined breast cancer subty** and diagnostics. However, wider use in clinical practice is hampered for a number of reasons including the application...
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Article
Open AccessRapid autopsies to enhance metastatic research: the UPTIDER post-mortem tissue donation program
Research on metastatic cancer has been hampered by limited sample availability. Here we present the breast cancer post-mortem tissue donation program UPTIDER and show how it enabled sampling of a median of 31 ...
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Article
Open AccessTGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression
Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer. Virtually all women with DCIS are treated, despite evidence suggesting up to half would remain with stable, non-threatenin...
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Article
Open AccessRNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer
Multigene assays for molecular subtypes and biomarkers can aid management of early invasive breast cancer. Using RNA-sequencing we aimed to develop single-sample predictor (SSP) models for clinical markers, su...
