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Article
Population fragmentation leads to isolation by distance but not genetic impoverishment in the philopatric Lesser Kestrel: a comparison with the widespread and sympatric Eurasian Kestrel
Population fragmentation is a widespread phenomenon usually associated with human activity. As a result of habitat transformation, the philopatric and steppe-specialist Lesser Kestrel Falco naumanni underwent a s...
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Article
Open AccessAssessment of free light chains in the cerebrospinal fluid of patients with lymphomatous meningitis – a pilot study
Lymphomatous meningitis (LM) represents a severe complication of malignant lymphomas. While clinical suspicion is raised by symptoms ranging from mild disturbances of sensation to severe pain or impaired consc...
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Article
Open AccessEnhanced photodynamic destruction of a transplantable fibrosarcoma using photochemical internalisation of gelonin
Photochemical internalisation (PCI) is a technique for releasing biologically active macromolecules from endocytic vesicles by light activation of a photosensitiser localised in the same vesicles of targeted c...
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Article
Open AccessNitrogen-containing bisphosphonates inhibit cell cycle progression in human melanoma cells
Cutaneous melanoma is one of the highly malignant human tumours, due to its tendency to generate early metastases and its resistance to classical chemotherapy. We recently demonstrated that pamidronate, a nitr...
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Article
Chemical defence in a sawfly: genetic components of variation in relevant life-history traits
Larvae of several tenthredinid sawfly species readily release droplets of haemolymph through their integument when attacked by predators. This defence mechanism via ‘bleeding’ is characterised by a low integum...
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Article
Open AccessDecreased DNA-PK activity in human cancer cells exhibiting hypersensitivity to low-dose irradiation
Low-dose hyper-radiosensitivity (HRS) (below 0.5 Gy) has been extensively documented in the past few years. The molecular basis of this phenomenon remains largely unknown and the purpose of this study was to i...