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  1. Article

    Open Access

    Metabolic impairment of non-small cell lung cancers by mitochondrial HSPD1 targeting

    The identification of novel targets is of paramount importance to develop more effective drugs and improve the treatment of non-small cell lung cancer (NSCLC), the leading cause of cancer-related deaths worldw...

    Beatrice Parma, Vignesh Ramesh in Journal of Experimental & Clinical Cancer … (2021)

  2. Article

    Open Access

    The role of miR-200b/c in balancing EMT and proliferation revealed by an activity reporter

    Since their discovery, microRNAs (miRNAs) have been widely studied in almost every aspect of biology and medicine, leading to the identification of important gene regulation circuits and cellular mechanisms. H...

    Paradesi Naidu Gollavilli, Beatrice Parma, Aarif Siddiqui, Hai Yang in Oncogene (2021)

  3. Article

    Open Access

    Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer

    Epithelial-to-mesenchymal transition (EMT) enhances motility, stemness, chemoresistance and metastasis. Little is known about how various pathways coordinate to elicit EMT’s different functional aspects in non...

    Mohammad Aarif Siddiqui, Paradesi Naidu Gollavilli in British Journal of Cancer (2021)

  4. Article

    Open Access

    Thymidylate synthase maintains the de-differentiated state of triple negative breast cancers

    Cancer cells frequently boost nucleotide metabolism (NM) to support their increased proliferation, but the consequences of elevated NM on tumor de-differentiation are mostly unexplored. Here, we identified a r...

    Aarif Siddiqui, Paradesi Naidu Gollavilli, Annemarie Schwab in Cell Death & Differentiation (2019)

  5. No Access

    Article

    Über die Nerven- und Muskelphysiologie des Pferdeegels Haemopis sanguisuga

    Bei Haemopis sanguisuga ist die Leitungsgeschwindigkeit im ungedehnten Rückenmuskel 48,6 ± 8,4 cm/sec, sie nimmt bei Dehnung proportional der erreichten Länge zu. Die Leitungsgeschwindigkeit im ungedehnten Nerven...

    Annemarie Schwab in Zeitschrift für vergleichende Physiologie (1949)