102 Result(s)
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English
**yuan Ren
Article
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Article
Open AccessGreen fluorescent protein as a reporter of prion protein folding
The amino terminal half of the cellular prion protein PrPc is implicated in both the binding of copper ions and the conformational changes that lead to disease but has no defined structure. However, as some struc...
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Open AccessEvaluation of high-risk Human papillomaviruses type distribution in cervical cancer in Sichuan province of China
Infection with high-risk human papillomavirus is an important factor associated with cervical cancer, and the distribution of HPV types varies greatly worldwide. Determination of type-specific HPV prevalence c...
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Open AccessShort Linear Motifs recognized by SH2, SH3 and Ser/Thr Kinase domains are conserved in disordered protein regions
Protein interactions are essential for most cellular functions. Interactions mediated by domains that appear in a large number of proteins are of particular interest since they are expected to have an impact o...
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Open AccessThe conservation pattern of short linear motifs is highly correlated with the function of interacting protein domains
Many well-represented domains recognize primary sequences usually less than 10 amino acids in length, called Short Linear Motifs (SLiMs). Accurate prediction of SLiMs has been difficult because they are short ...
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Open AccessThe diploid genome sequence of an Asian individual
Here we present the first diploid genome sequence of an Asian individual. The genome was sequenced to 36-fold average coverage using massively parallel sequencing technology. We aligned the short reads onto th...
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Open AccessThe sequence and de novo assembly of the giant panda genome
Using next-generation sequencing technology alone, we have successfully generated and assembled a draft sequence of the giant panda genome. The assembled contigs (2.25 gigabases (Gb)) cover approximately 94% o...
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Erratum: The sequence and de novo assembly of the giant panda genome
Nature 463, 311–317 (2010) In this Article, the Latin species name of the giant panda was written incorrectly as Ailuropoda melanoleura. The correct name is Ailuropoda melanoleuca.
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Open AccessInternode Distance-Based Redundancy Reliable Transport in Underwater Sensor Networks
Underwater communication is a very challenging topic. Protocols used in terrestrial sensor networks cannot be directly applied in the underwater world. High-bit error rate and large propagation delay make the ...
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Open AccessPreferential Growth of Semiconducting Single-Walled Carbon Nanotubes on Substrate by Europium Oxide
In this paper, we have demonstrated that europium oxide (Eu2O3) is a new type of active catalyst for single-walled carbon nanotubes (SWNTs) growth under suitable conditions. Both random SWNT networks and horizont...
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Open AccessDistributed KDC-Based Random Pairwise Key Establishment in Wireless Sensor Networks
Key management is a core mechanism to provide secure and reliable communications in wireless sensor networks (WSNs). In large-scale WSNs, due to the resource constraint on sensor nodes, it is still an extremel...
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Open AccessComparison of two approaches for measuring household wealth via an asset-based index in rural and peri-urban settings of Hunan province, China
There are growing concerns regarding inequities in health, with poverty being an important determinant of health as well as a product of health status. Within the People's Republic of China (P.R. China), dispa...
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Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner
Angiogenesis, a process by which the preexisting blood vasculature gives rise to new capillary vessels, is associated with a variety of physiologic and pathologic conditions. However, the molecular mechanism u...
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Open AccessStudy on Driving Dangerous Area in Road Curved Section Based on Vehicle Track Characteristics
Plenty of experiments and data analysis of vehicle track type in road curved section show that the deviation and the crossing characteristics of vehicle track paths are directly related to the driving stabilit...
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Open AccessTranscriptional profiling by cDNA-AFLP analysis showed differential transcript abundance in response to water stress in Populus hopeiensis
Drought is one of the main environmental factors limiting tree growth and productivity of plantation forests worldwide. Populus hopeiensis Hu et Chow is one of the most important commercial plantation tree specie...
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Open AccessPegylated interferon α enhances recovery of memory T cells in e antigen positive chronic hepatitis B patients
Interferons (IFNs) are a group of cytokines commonly used in the clinical treatment of chronic hepatitis B (CHB) patients. Their therapeutic effects are highly correlated with recovery of host antiviral immuni...
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Open AccessPXR and CAR single nucleotide polymorphisms influence plasma efavirenz levels in South African HIV/AIDS patients
This study investigated variation in NR1I2 and NR1I3 and its effect on plasma efavirenz levels in HIV/AIDS patients. Variability in plasma drug levels has largely led research on identifying causative variants in...
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Open AccessPrecise measurement of stable (δ 88/86Sr) and radiogenic (87Sr/86Sr) strontium isotope ratios in geological standard reference materials using MC-ICP-MS
A new method for high-precision measurements of stable (δ 88/86Sr) and radiogenic (87Sr/86Sr) Sr isotope ratios was developed on the MC-ICP-MS using a standard-sample-standard bracketing protocol....
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Open AccessDiscovery and study of cutaneous leishmaniasis in Karamay of **njiang, West China
Cutaneous leishmaniasis (CL) was discovered in the farms of the Karamay suburb, **njiang Uygur Autonomous Region in the 1990s. Between 1992 and 1994, a house-to-house survey revealed a prevalence of 1.0-1.6% i...
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Open AccessJAK1 truncating mutations in gynecologic cancer define new role of cancer-associated protein tyrosine kinase aberrations
Cancer-associated protein tyrosine kinase (PTK) mutations usually are gain-of-function (GOF) mutations that drive tumor growth and metastasis. We have found 50 JAK1 truncating mutations in 36 of 635 gynecologi...
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Open AccessClinical implications of AGBL2 expression and its inhibitor latexin in breast cancer
We investigated the expression status of AGBL2 and its inhibitor latexin in breast cancer stem cells and its clinical implications in order to lay a foundation for managing breast cancer.
