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Open AccessNon-Abelian braiding of Fibonacci anyons with a superconducting processor
Quantum many-body systems with a non-Abelian topological order can host anyonic quasiparticles. It has been proposed that anyons could be used to encode and manipulate information in a topologically protected ...
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Article
Open AccessSerum vitamin D concentrations and sleep disorders: insights from NHANES 2011–2016 and Mendelian Randomization analysis
This investigation seeks to examine the association between serum vitamin D concentrations and the prevalence of sleep disorders, additionally elucidating the causal relationship via Mendelian Randomization (M...
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Open AccessEmerging therapeutic frontiers in cancer: insights into posttranslational modifications of PD-1/PD-L1 and regulatory pathways
The interaction between programmed cell death ligand 1 (PD-L1), which is expressed on the surface of tumor cells, and programmed cell death 1 (PD-1), which is expressed on T cells, impedes the effective activa...
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Open AccessA flocking control algorithm of multi-agent systems based on cohesion of the potential function
Flocking cohesion is critical for maintaining a group’s aggregation and integrity. Designing a potential function to maintain flocking cohesion unaffected by social distance is challenging due to the uncertain...
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Open AccessThe mechanism of action and experimental verification of Gan-song Yin on renal clear cell carcinoma based on network pharmacology and bioinformatics
Gan-song Yin (GSY) is originated from the scripture “Gan-song Pills”, a medical work of the Ningxia ethnic minorities, and its treatment of kidney diseases has good results. Its method of treating Renal clear ...
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Open AccessSeveral first-line anti-hypertensives act on fibrosarcoma progression and PD1ab blockade therapy
Patients are typically diagnosed with both hypertension and fibrosarcoma. Medical oncologists must prescribe suitable anti-hypertensive medications while considering anti-tumor drugs. Recently, immunotherapy h...
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Open AccessThe roles and molecular mechanisms of non-coding RNA in cancer metabolic reprogramming
One of the key features of cancer is energy metabolic reprogramming which is tightly related to cancer proliferation, invasion, metastasis, and chemotherapy resistance. NcRNAs are a class of RNAs having no pro...
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Article
Open AccessFerritinophagy: research advance and clinical significance in cancers
Ferritinophagy, a process involving selective autophagy of ferritin facilitated by nuclear receptor coactivator 4 (NCOA4), entails the recognition of ferritin by NCOA4 and subsequent delivery to the autophagos...
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Open AccessA comprehensive assessment of exome capture methods for RNA sequencing of formalin-fixed and paraffin-embedded samples
RNA-Seq analysis of Formalin-Fixed and Paraffin-Embedded (FFPE) samples has emerged as a highly effective approach and is increasingly being used in clinical research and drug development. However, the process...
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Open AccessPotential crop yield gains under intensive soybean/maize intercrop** in China
Intensive soybean/maize intercrop**, a specific form of intercrop**, holds promise in addressing the challenges posed by increasing food demands, diminishing cropland areas, deteriorating soil quality, and...
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Article
Open AccessNitric oxide-dependent immunosuppressive function of thymus-derived mesenchymal stromal/stem cells
The thymus is required for T cell development and the formation of the adaptive immunity. Stromal cells, which include thymic epithelial cells (TECs) and mesenchymal stromal cells (MSCs), are essential for thy...
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Open AccessCircadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling
As a subclass of endogenous stable noncoding RNAs, circular RNAs are beginning to be appreciated for their potential as tumor therapeutics. However, the functions and mechanisms by which circRNAs exert protect...
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Open AccessThe space cold atom interferometer for testing the equivalence principle in the China Space Station
The precision of the weak equivalence principle (WEP) test using atom interferometers (AIs) is expected to be extremely high in microgravity environment. The microgravity scientific laboratory cabinet (MSLC) i...
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Open AccessProteomic profiling of gastric cancer with peritoneal metastasis identifies a protein signature associated with immune microenvironment and patient outcome
Peritoneal metastasis (PM) frequently occurs in patients with gastric cancer (GC) and is a major cause of mortality. Risk stratification for PM can optimize decision making in GC treatment.
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Open AccessMetabolic reprogramming and epigenetic modifications in cancer: from the impacts and mechanisms to the treatment potential
Metabolic reprogramming and epigenetic modifications are hallmarks of cancer cells. In cancer cells, metabolic pathway activity varies during tumorigenesis and cancer progression, indicating regulated metaboli...
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Correction to: HYOU1 promotes cell proliferation, migration, and invasion via the PI3K/AKT/FOXO1 feedback loop in bladder cancer
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Open AccessComparisons of objective and subjective refraction with and without cycloplegia using binocular wavefront optometer with autorefraction and retinoscopy in school-age children
To compare school-age children’s objective and subjective refraction using a binocular wavefront optometer (BWFOM) with autorefraction and retinoscopy before and after cycloplegia.
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Open AccessArtificial intelligence-based refractive error prediction and EVO-implantable collamer lens power calculation for myopia correction
Implantable collamer lens (ICL) has been widely accepted for its excellent visual outcomes for myopia correction. It is a new challenge in phakic IOL power calculation, especially for those with low and modera...
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Open AccessExosomal cargos-mediated metabolic reprogramming in tumor microenvironment
Metabolic reprogramming is one of the hallmarks of cancer. As nutrients are scarce in the tumor microenvironment (TME), tumor cells adopt multiple metabolic adaptations to meet their growth requirements. Metab...
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Open AccessMatters arising: methodological issues on evaluating agreement between medical students’ attitudes towards drugs/alcohol use during pregnancy by Cohen’s kappa analysis
The purpose of this article is to discuss the statistical methods for agreement analysis used in Richelle’s article (BMC Med Educ 22:335, 2022). The authors investigated the attitudes of final-year medical stu...