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Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1

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  1. Article

    Open Access

    Non-Abelian braiding of Fibonacci anyons with a superconducting processor

    Quantum many-body systems with a non-Abelian topological order can host anyonic quasiparticles. It has been proposed that anyons could be used to encode and manipulate information in a topologically protected ...

    Shibo Xu, Zheng-Zhi Sun, Ke Wang, Hekang Li, Zitian Zhu, Hang Dong in Nature Physics (2024)

  2. Article

    Open Access

    Serum vitamin D concentrations and sleep disorders: insights from NHANES 2011–2016 and Mendelian Randomization analysis

    This investigation seeks to examine the association between serum vitamin D concentrations and the prevalence of sleep disorders, additionally elucidating the causal relationship via Mendelian Randomization (M...

    Junjie Jiang, Hanyu Tan, Zhongfang **a, Jun Li, Shuang Zhou in Sleep and Breathing (2024)

  3. Article

    Open Access

    Emerging therapeutic frontiers in cancer: insights into posttranslational modifications of PD-1/PD-L1 and regulatory pathways

    The interaction between programmed cell death ligand 1 (PD-L1), which is expressed on the surface of tumor cells, and programmed cell death 1 (PD-1), which is expressed on T cells, impedes the effective activa...

    Rong Wang, Shiwei He, Jun Long, Yian Wang in Experimental Hematology & Oncology (2024)

  4. Article

    Open Access

    A flocking control algorithm of multi-agent systems based on cohesion of the potential function

    Flocking cohesion is critical for maintaining a group’s aggregation and integrity. Designing a potential function to maintain flocking cohesion unaffected by social distance is challenging due to the uncertain...

    Chenyang Li, Yonghui Yang, Guanjie Jiang, Xue-Bo Chen in Complex & Intelligent Systems (2024)

  5. Article

    Open Access

    The mechanism of action and experimental verification of Gan-song Yin on renal clear cell carcinoma based on network pharmacology and bioinformatics

    Gan-song Yin (GSY) is originated from the scripture “Gan-song Pills”, a medical work of the Ningxia ethnic minorities, and its treatment of kidney diseases has good results. Its method of treating Renal clear ...

    Wenjie Jiang, Ling Yuan, Qian Liu, **angyang Li, Yifan Yang in Discover Oncology (2024)

  6. Article

    Open Access

    Several first-line anti-hypertensives act on fibrosarcoma progression and PD1ab blockade therapy

    Patients are typically diagnosed with both hypertension and fibrosarcoma. Medical oncologists must prescribe suitable anti-hypertensive medications while considering anti-tumor drugs. Recently, immunotherapy h...

    Jianwen Sun, Chaoxiong Zhang, **nhao Su in Journal of Orthopaedic Surgery and Research (2024)

  7. Article

    Open Access

    The roles and molecular mechanisms of non-coding RNA in cancer metabolic reprogramming

    One of the key features of cancer is energy metabolic reprogramming which is tightly related to cancer proliferation, invasion, metastasis, and chemotherapy resistance. NcRNAs are a class of RNAs having no pro...

    Shizhen Li, Ming**g Peng, Shiming Tan, Linda Oyang in Cancer Cell International (2024)

  8. Article

    Open Access

    Ferritinophagy: research advance and clinical significance in cancers

    Ferritinophagy, a process involving selective autophagy of ferritin facilitated by nuclear receptor coactivator 4 (NCOA4), entails the recognition of ferritin by NCOA4 and subsequent delivery to the autophagos...

    Jiewen Wang, Nayiyuan Wu, Ming**g Peng, Linda Oyang, in Cell Death Discovery (2023)

  9. Article

    Open Access

    A comprehensive assessment of exome capture methods for RNA sequencing of formalin-fixed and paraffin-embedded samples

    RNA-Seq analysis of Formalin-Fixed and Paraffin-Embedded (FFPE) samples has emerged as a highly effective approach and is increasingly being used in clinical research and drug development. However, the process...

    Liang Zong, Yabing Zhu, Yuan Jiang, Ying **a, Qun Liu, Sanjie Jiang in BMC Genomics (2023)

  10. Article

    Open Access

    Potential crop yield gains under intensive soybean/maize intercrop** in China

    Intensive soybean/maize intercrop**, a specific form of intercrop**, holds promise in addressing the challenges posed by increasing food demands, diminishing cropland areas, deteriorating soil quality, and...

    Guohui Chen, Fahui Jiang, Song Zhang, Qin Zhang, Guanjie Jiang in Plant and Soil (2023)

  11. Article

    Open Access

    Nitric oxide-dependent immunosuppressive function of thymus-derived mesenchymal stromal/stem cells

    The thymus is required for T cell development and the formation of the adaptive immunity. Stromal cells, which include thymic epithelial cells (TECs) and mesenchymal stromal cells (MSCs), are essential for thy...

    **ao Su, **aolei Li, Shiqing Wang, **aotong Xue, Rui Liu, **ao**g Bai in Biology Direct (2023)

  12. Article

    Open Access

    Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling

    As a subclass of endogenous stable noncoding RNAs, circular RNAs are beginning to be appreciated for their potential as tumor therapeutics. However, the functions and mechanisms by which circRNAs exert protect...

    Deze Zhao, Ye** Dong, Minghao Duan, Dan He in Journal of Experimental & Clinical Cancer … (2023)

  13. Article

    Open Access

    The space cold atom interferometer for testing the equivalence principle in the China Space Station

    The precision of the weak equivalence principle (WEP) test using atom interferometers (AIs) is expected to be extremely high in microgravity environment. The microgravity scientific laboratory cabinet (MSLC) i...

    Meng He, ** Chen, Jie Fang, Qunfeng Chen, Huanyao Sun, Yibo Wang in npj Microgravity (2023)

  14. Article

    Open Access

    Proteomic profiling of gastric cancer with peritoneal metastasis identifies a protein signature associated with immune microenvironment and patient outcome

    Peritoneal metastasis (PM) frequently occurs in patients with gastric cancer (GC) and is a major cause of mortality. Risk stratification for PM can optimize decision making in GC treatment.

    Yanyan Chen, Guoxin Cai, Junjie Jiang, Chao He, Yiran Chen, Yongfeng Ding in Gastric Cancer (2023)

  15. Article

    Open Access

    Metabolic reprogramming and epigenetic modifications in cancer: from the impacts and mechanisms to the treatment potential

    Metabolic reprogramming and epigenetic modifications are hallmarks of cancer cells. In cancer cells, metabolic pathway activity varies during tumorigenesis and cancer progression, indicating regulated metaboli...

    Xuemeng Xu, Qiu Peng, **anjie Jiang, Shiming Tan in Experimental & Molecular Medicine (2023)

  16. Article

    Correction to: HYOU1 promotes cell proliferation, migration, and invasion via the PI3K/AKT/FOXO1 feedback loop in bladder cancer

    Weiguo Wang, **njie Jiang, Fei **a, Xudong Chen, Guojun Li in Molecular Biology Reports (2023)

  17. Article

    Open Access

    Comparisons of objective and subjective refraction with and without cycloplegia using binocular wavefront optometer with autorefraction and retinoscopy in school-age children

    To compare school-age children’s objective and subjective refraction using a binocular wavefront optometer (BWFOM) with autorefraction and retinoscopy before and after cycloplegia.

    Yadi Lei, Xun Chen, Mingrui Cheng in Graefe's Archive for Clinical and Experime… (2023)

  18. Article

    Open Access

    Artificial intelligence-based refractive error prediction and EVO-implantable collamer lens power calculation for myopia correction

    Implantable collamer lens (ICL) has been widely accepted for its excellent visual outcomes for myopia correction. It is a new challenge in phakic IOL power calculation, especially for those with low and modera...

    Yinjie Jiang, Yang Shen, Xun Chen, Lingling Niu, Boliang Li in Eye and Vision (2023)

  19. Article

    Open Access

    Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment

    Metabolic reprogramming is one of the hallmarks of cancer. As nutrients are scarce in the tumor microenvironment (TME), tumor cells adopt multiple metabolic adaptations to meet their growth requirements. Metab...

    Shiming Tan, Yiqing Yang, Wenjuan Yang in Journal of Experimental & Clinical Cancer … (2023)

  20. Article

    Open Access

    Matters arising: methodological issues on evaluating agreement between medical students’ attitudes towards drugs/alcohol use during pregnancy by Cohen’s kappa analysis

    The purpose of this article is to discuss the statistical methods for agreement analysis used in Richelle’s article (BMC Med Educ 22:335, 2022). The authors investigated the attitudes of final-year medical stu...

    Tianfei Yu, Lei Yang, **njie Jiang, Shuli Shao, Wei Sha, Ming Li in BMC Medical Education (2023)

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