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Open AccessAssociation between sarcopenia and osteoarthritis among the US adults: a cross-sectional study
The association between sarcopenia and OA still presents many uncertainties. We aimed to assess whether sarcopenia is associated with occurrence of OA in US adults. We conducted a cross-sectional study consist...
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Open AccessTongbi Huoluo Decoction alleviates cartilage degeneration in knee osteoarthritis by inhibiting degradation of extracellular matrix
Knee osteoarthritis (KOA) is an age-related degenerative disease characterized by abrasion of articular cartilage. Tongbi Huoluo Decoction (TBHLD) has been transformed from the famous traditional Chinese medic...
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Open AccessMetabolic reprogramming and epigenetic modifications in cancer: from the impacts and mechanisms to the treatment potential
Metabolic reprogramming and epigenetic modifications are hallmarks of cancer cells. In cancer cells, metabolic pathway activity varies during tumorigenesis and cancer progression, indicating regulated metaboli...
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Open AccessExosomal cargos-mediated metabolic reprogramming in tumor microenvironment
Metabolic reprogramming is one of the hallmarks of cancer. As nutrients are scarce in the tumor microenvironment (TME), tumor cells adopt multiple metabolic adaptations to meet their growth requirements. Metab...
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Open AccessDoes tourniquet use affect the periprosthetic bone cement penetration in total knee arthroplasty? A meta-analysis
A tourniquet is a device commonly used to control massive hemorrhage during knee replacement surgery. However, the question remains whether the use of tourniquets affects the permeability of the bone cement ar...
