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Article
A Nonparametric Model Checking Test for Functional Linear Composite Quantile Regression Models
This paper is focused on the goodness-of-fit test of the functional linear composite quantile regression model. A nonparametric test is proposed by using the orthogonality of the residual and its conditional e...
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Article
In vivo AAV–SB-CRISPR screens of tumor-infiltrating primary NK cells identify genetic checkpoints of CAR-NK therapy
Natural killer (NK) cells have clinical potential against cancer; however, multiple limitations hinder the success of NK cell therapy. Here, we performed unbiased functional map** of tumor-infiltrating NK (T...
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Article
Rank-based instrumental variable estimation for semiparametric varying coefficient spatial autoregressive models
In this paper, it is aim to propose an instrumental variable rank estimation method for varying coefficient spatial autoregressive models. The newly proposed method provides a highly efficient and robust alter...
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Article
Open AccessIdentification and validation of RNA-binding protein SLC3A2 regulates melanocyte ferroptosis in vitiligo by integrated analysis of single-cell and bulk RNA-sequencing
The pathogenesis of vitiligo remains unclear. The genes encoding vitiligo-related RNA-binding proteins (RBPs) and their underlying pathogenic mechanism have not been determined.
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Article
Local Influence Detection of Conditional Mean Dependence
This article is focused on the problem to measure and test the conditional mean dependence of a response variable on a predictor variable. A local influence detection approach is developed combining with the m...
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Article
Open AccessInhibition of PDGFRβ alleviates endothelial cell apoptotic injury caused by DRP-1 overexpression and mitochondria fusion failure after mitophagy
Kawasaki disease (KD), described as “mucocutaneous lymph node syndrome”, affects infants and toddlers. Patients with KD suffer from an inflammatory cascade leading to vasculitis with a predilection for coronary a...
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Article
Modeling and Simulation of Macroscopic Friction Coefficient of Brake Pair Considering Particle Flows and Interface Parameters
In this paper, a three-dimensional model of the disc brake pair considering the particle flows is firstly established, and the finite element simulation analysis of the brake pair friction performance is carri...
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Article
Correction: Modeling and Simulation of Macroscopic Friction Coefficient of Brake Pair Considering Particle Flows and Interface Parameters
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Article
Open AccessProtective effects of isorhamnetin against H2O2-induced oxidative damage in HaCaT cells and comprehensive analysis of key genes
Isorhamnetin (ISO) is a methylated flavonol present in the leaves, flowers, and fruits of many plants with antitumour, anti-inflammatory, antioxidant, and anti-apoptotic properties. ISO has been suggested as t...
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Article
Statistical inference in the partial functional linear expectile regression model
As extensions of means, expectiles embrace all the distribution information of a random variable. The expectile regression is computationally friendlier because the asymmetric least square loss function is dif...
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Article
Open AccessA comparative study of interfacial thermal conductance between metal and semiconductor
To understand and control thermal conductance of interface between metal and semiconductor has now become a crucial task for the thermal design and management of nano-electronic and micro-electronic devices. T...
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Article
An Alternative Doubly Robust Estimation in Causal Inference Model
Doubly robust (DR) methods that employ both the propensity score and outcome models are widely used to estimate the causal effect of a treatment and generally outperform those methods only using the propensity...
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Article
A Leader–Follower Sequential Game Approach to Optimizing Parameters for Intelligent Vehicle Formation Control
A vehicle formation control algorithm is presented to deal with the ineluctable uncertainty and guarantee the vehicle platoon Lyapunov stability (uniform boundedness, uniform ultimate boundedness, and string s...
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Article
Estimation in Partially Observed Functional Linear Quantile Regression
Currently, working with partially observed functional data has attracted a greatly increasing attention, since there are many applications in which each functional curve may be observed only on a subset of a c...
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Article
Open AccessAsynchronous responses of aquatic ecosystems to hydroclimatic forcing on the Tibetan Plateau
High-altitude ecosystems react sensitively to hydroclimatic triggers. Here we evaluated the ecological and hydrological changes in a glacier-influenced lake (Hala Hu, China) since the last glacial. Rapid fluct...
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Article
Current Perspectives on Severe Drug Eruption
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threat...
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Article
Optimal Endometrial Preparation Protocols for Frozen-thawed Embryo Transfer Cycles by Maternal Age
This retrospective cohort study aimed to explore the optimal endometrial preparation protocols among different maternal age groups. A total of 16,867 frozen-thawed embryo transfer (FET) cycles were categorized...
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Article
Testing independence and goodness-of-fit jointly for functional linear models
A conventional regression model for functional data involves expressing a response variable in terms of the predictor function. Two assumptions, that (i) the predictor function and the error are independent an...
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Article
Testing linearity in partial functional linear quantile regression model based on regression rank scores
This paper investigates the hypothesis test of the parametric component in partial functional linear quantile regression model in which the dependent variable is related to both a vector of finite length and a...
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Article
A Constrained Interval-Valued Linear Regression Model: A New Heteroscedasticity Estimation Method
Linear regression models for interval-valued data have been widely studied. Most literatures are to split an interval into two real numbers, i.e., the left- and right-endpoints or the center and radius of this...