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  1. Article

    Open Access

    Causal relationship between bone mineral density and intervertebral disc degeneration: a univariate and multivariable mendelian randomization study

    Although previous studies have suggested a possible association between bone mineral density (BMD) and intervertebral disc degeneration (IDD), the causal relationship between them remains unclear. Evidence fro...

    Luming Li, Dawei Li, Ziming Geng, Zhenxin Huo in BMC Musculoskeletal Disorders (2024)

  2. No Access

    Article

    Sedimentary characteristics and development model of the bedded evaporites in the Paleogene Kumugeliemu formation, Kuqa depression, Northwestern China

    In recent years, extensive exploration has contributed to significant advancements in the geological formations of the Kuqa Depression. In particular, the Paleogene Kumugeliemu Formation exhibits the developme...

    Liang Luo, **gxiang Guo, Chenlin Hu, Huixi Lin in Carbonates and Evaporites (2024)

  3. Article

    Open Access

    Identification of diagnostic markers for moyamoya disease by combining bulk RNA-sequencing analysis and machine learning

    Moyamoya disease (MMD) remains a chronic progressive cerebrovascular disease with unknown etiology. A growing number of reports describe the development of MMD relevant to infection or autoimmune diseases. Ide...

    Yifan Xu, Bing Chen, Zhongxiang Guo, Cheng Chen, Chao Wang, Han Zhou in Scientific Reports (2024)

  4. No Access

    Article

    Cadmium negatively affects the growth and physiological status and the alleviation effects by exogenous selenium in silage maize (Zea mays L.)

    Increasing soil cadmium (Cd) contamination is a serious threat to human food health and safety. In order to reduce Cd uptake and Cd toxicity in silage maize, hydroponic tests were conducted to investigate the ...

    Weihuan **, Lan Cheng, Chunyan Liu in Environmental Science and Pollution Resear… (2024)

  5. Article

    Open Access

    The value of indocyanine green-FLOW800 in microvasculature for predicting cerebral hyperperfusion syndrome in moyamoya disease patients

    Among the notable complications of direct hemodynamic reconstruction for moyamoya disease (MMD) is cerebral hyperperfusion syndrome (CHS). In this study, we evaluated hemodynamic changes in small regional micr...

    Zhongxiang Guo, Zhaohui Yan, Fan Qu, Dekui Cheng, Chao Wang in Scientific Reports (2023)

  6. No Access

    Article

    Identification of Myxobolus distalisensis n. sp. (Cnidaria: Myxozoa) infecting yellow catfish Tachysurus fulvidraco (Richardson), with a supplement description of M. voremkhai (Akhmerov, 1960) Landsberg and Lom, 1991

    With growing scale of intensive fish cultivation, the risk of parasite infection in commercial fish is increased. Precisely identifying and characterizing the parasites that infect the farmed fish is critical ...

    Bo Zhang, Qingxiang Guo, **ao Tu, Zemao Gu in Systematic Parasitology (2023)

  7. No Access

    Article

    ASO Visual Abstract: Sintilimab Plus Modified FOLFIRINOX in Metastatic or Recurrent Pancreatic Cancer: The Randomized Phase II CISPD3 Trial

    Qihan Fu MD, Yiwen Chen MD, Dabing Huang MS in Annals of Surgical Oncology (2023)

  8. No Access

    Article

    Sintilimab Plus Modified FOLFIRINOX in Metastatic or Recurrent Pancreatic Cancer: The Randomized Phase II CISPD3 Trial

    Folinic acid, fluorouracil, irinotecan, and oxaliplatin (FOLFIRINOX) or modified FOLFIRINOX (mFFX) is the first-line standard of care for metastatic pancreatic adenocarcinoma; effective and safe treatment stra...

    Qihan Fu MD, Yiwen Chen MD, Dabing Huang MS in Annals of Surgical Oncology (2023)

  9. No Access

    Article

    Research advances in identification procedures of endocrine disrupting chemicals

    Endocrine disrupting chemicals (EDCs) are increasingly concerned substance endangering human health and environment. However, there is no unified standard for identifying chemicals as EDCs, which is also contr...

    **ng Guo, Bing Liu, Haohao Liu, **ngde Du in Environmental Science and Pollution Resear… (2023)

  10. Article

    Open Access

    PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression

    Protein arginine methyltransferase 2 (PRMT2) is involved in several biological processes via histone methylation and transcriptional regulation. Although PRMT2 has been reported to affect breast cancer and gli...

    Zhongwei Li, Chaozhen Chen, Hongmei Yong, Lei Jiang, Pengfei Wang in Cell Death & Disease (2023)

  11. No Access

    Article

    Lycorine induces apoptosis of acute myeloid leukemia cells and inhibits triglyceride production via binding and targeting FABP5

    Acute myeloid leukemia (AML) is the most common hematopoietic malignancy with abnormal lipid metabolism. However, currently available information on the involvement of the alterations in lipid metabolism in AM...

    **nming Liang, Wenli Fu, YuHui Peng, Juanjuan Duan, Ting Zhang in Annals of Hematology (2023)

  12. No Access

    Article

    Exosomes from bone marrow-derived mesenchymal stem cells facilitate corneal wound healing via regulating the p44/42 MAPK pathway

    This study was aimed at exploring the function of Exosomes isolated from bone marrow-derived mesenchymal stem cells (BMSC-Exos) in corneal wound healing and at revealing the underlying mechanisms involving the...

    ** Zhou, Yuanyuan Ding, Yongqiang Zhang in Graefe's Archive for Clinical and Experime… (2023)

  13. No Access

    Article

    Semisupervised anomaly detection of multivariate time series based on a variational autoencoder

    In a large-scale cloud environment, many key performance indicators (KPIs) of entities are monitored in real time. These multivariate time series consist of high-dimensional, high-noise, random and time-depend...

    Ningjiang Chen, Huan Tu, **aoyan Duan, Liangqing Hu, Chengxiang Guo in Applied Intelligence (2023)

  14. Article

    Open Access

    Targeting ubiquitin-specific protease 8 sensitizes anti-programmed death-ligand 1 immunotherapy of pancreatic cancer

    Programmed death-1 (PD-1) and its ligand programmed death-ligand 1 (PD-L1) help tumor cells evade immune surveillance, and are regarded as important targets of anti-tumor immunotherapy. Post-translational modi...

    Hanshen Yang, **aozhen Zhang, Mengyi Lao, Kang Sun in Cell Death & Differentiation (2023)

  15. Article

    Open Access

    Normalization of tumor markers and a clear resection margin affect progression-free survival of patients with unresectable pancreatic cancer who have undergone conversion surgery

    With the advent of intensive combination regimens, an increasing number of patients with unresectable pancreatic cancer (UPC) have regained the opportunity for surgery. We investigated the clinical benefits an...

    **ang Li, **nyuan Liu, Na Lu, Yiwen Chen, **aochen Zhang, Chengxiang Guo in BMC Cancer (2023)

  16. Article

    Open Access

    Insights into the deriving of rhizosphere microenvironments and its effects on the growth of authentic Angelica sinensis seedlings under continuous monoculture

    Continuous monoculture leads to deterioration of soil microenvironment, which can severely threat the quality and efficiency of Angelica sinensis (A. sinensis), especially for seedlings production. However, littl...

    **aofang Gong, Ying Zhu, Yinan Peng, Zengxiang Guo, Jian** Zhou in Annals of Microbiology (2022)

  17. Article

    Open Access

    Research on the effectiveness of a intersection risk warning system based on driving simulation experiment

    In order to improve the traffic safety condition of intersections, a real-time traffic conflict risk warning system (RTCRWS) is proposed for uncontrolled intersections. To evaluate the effectiveness of this sy...

    Yiwen Zhou, Fengxiang Guo, Wenchen Yang, Huasen Wan in Scientific Reports (2022)

  18. No Access

    Article

    OSBN: architecture and control mechanism of optical switched satellite backbone network

    With the success of commercial spaceflights, space information infrastructure (SII) has received much attention in recent years. Blueprints such as the low earth orbit global communication network and the data...

    Cen Wang, Noboru Yoshikane, Hongxiang Guo, **ong Gao in Photonic Network Communications (2022)

  19. No Access

    Article

    Partially reduced graphene oxide-based electrolyte: synthesis and electrochemical capacitance performance

    The increasing demand for higher-energy-density supercapacitors driven by advancements in devices necessitates the development of alternative electrolytes with a higher specific capacity or larger voltage wind...

    Xueyu Zhang, Mengru Ding, Shousheng Liu, Fengxiang Guo in Journal of Materials Science (2022)

  20. Article

    Open Access

    A clinical and biomechanical comparison of INFIX plus single versus double sacroiliac screw fixation for unstable pelvic ring injury

    The aim of this study is to compare the clinical and biomechanical outcome of INFIX plus single with two sacroiliac screw fixation for unstable pelvic fractures of Type C.

    Hongfen Chen, Chao Ding, Yongqiang Liu in Journal of Orthopaedic Surgery and Research (2022)

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