257 Result(s)
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Open AccessIn silico and microarray-based genomic approaches to identifying potential vaccine candidates against Leptospira interrogans
Currently available vaccines against leptospirosis are of low efficacy, have an unacceptable side-effect profile, do not induce long-term protection, and provide no cross-protection against the different serov...
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Open AccessIdentification of genes differentially expressed during larval molting and metamorphosis of Helicoverpa armigera
Larval molting and metamorphosis are important physiological processes in the life cycle of the holometabolous insect. We used suppression subtractive hybridization (SSH) to identify genes differentially expre...
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Open AccessIdentification and expression profile of a putative basement membrane protein gene in the midgut of Helicoverpa armigera
The midgut undergoes histolysis and remodeling during the larval to adult transition in holometabolous insects, but the molecular mechanisms underlying this process are not well understood.
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Open AccessGenetic diversity among major endemic strains of Leptospira interrogans in China
Leptospirosis is a world-widely distributed zoonosis. Humans become infected via exposure to pathogenic Leptospira spp. from contaminated water or soil. The availability of genomic sequences of Leptospira interro...
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Open AccessComplete sequence and organization of Antheraea pernyi nucleopolyhedrovirus, a dr-rich baculovirus
The completion and reporting of baculovirus genomes is extremely important as it advances our understanding of gene function and evolution. Due to the large number of viral genomes now sequenced it is very imp...
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Griseusin D, a New Pyranonaphthoquinone Derivative from a Alkaphilic Nocardiopsis sp.
A new pyranonaphthoquinone antibiotic, griseusin D (1) was isolated from the cultural fluid of the alkaphilic Nocardiopsis sp. The structure was determined as 5′-one-4-hydroxy-12-methoxygriseusin by spectroscopic...
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Open AccessDynamics and evolution of the inverted repeat-large single copy junctions in the chloroplast genomes of monocots
Various expansions or contractions of inverted repeats (IRs) in chloroplast genomes led to fluxes in the IR-LSC (large single copy) junctions. Previous studies revealed that some monocot IRs contain a trnH-rps19 ...
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Open AccessEvolutional selection of a combinatorial phage library displaying randomly-rearranged various single domains of immunoglobulin (Ig)-binding proteins (IBPs) with four kinds of Ig molecules
Protein A, protein G and protein L are three well-defined immunoglobulin (Ig)-binding proteins (IBPs), which show affinity for specific sites on Ig of mammalian hosts. Although the precise functions of these m...
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Open AccessIdentification and association of the single nucleotide polymorphisms in calpain3 (CAPN3) gene with carcass traits in chickens
The aim of this study is to screen single nucleotide polymorphisms (SNP) of chicken Calpain3 (CAPN3) gene and to analyze the potential association between CAPN3 gene polymorphisms and carcass traits in chickens. ...
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Open AccessDevelopment of O-antigen gene cluster-specific PCRs for rapid ty** six epidemic serogroups of Leptospira in China
Leptospira is the causative agent of leptospirosis. The O-antigen is the distal part of the lipopolysaccharide, which is a key component of outer membrane of Gram-negative bacteria and confers serological specifi...
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Polyglutamine toxicity in non-neuronal cells
The neurodegenerative polyglutamine diseases are caused by an expansion of unstable polyglutamine repeats in various disease proteins. Although these mutant proteins are expressed ubiquitously in neuronal and ...
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Antimycin A18 produced by an endophytic Streptomyces albidoflavus isolated from a mangrove plant
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Open AccessIdentification of four novel small non-coding RNAs from Xanthomonas campestris pathovar campestris
In bacteria, small non-coding RNAs (sRNAs) have been recognized as important regulators of various cellular processes. Approximately 200 bacterial sRNAs in total have been reported. However, very few sRNAs hav...
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Potassium channel α-subunit AtKC1 negatively regulates AKT1-mediated K+ uptake in Arabidopsis roots under low-K+ stress
Potassium transporters play crucial roles in K+ uptake and translocation in plants. However, so far little is known about the regulatory mechanism of potassium transporters. Here, we show that a Shaker-like potas...
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Open AccessComplete mitochondrial genomes of Taenia multiceps, T. hydatigena and T. pisiformis: additional molecular markers for a tapeworm genus of human and animal health significance
Mitochondrial genomes provide a rich source of molecular variation of proven and widespread utility in molecular ecology, population genetics and evolutionary biology. The tapeworm genus Taenia includes a diversi...
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Rice leaf inclination2, a VIN3-like protein, regulates leaf angle through modulating cell division of the collar
As an important agronomic trait, inclination of leaves is crucial for crop architecture and grain yields. To understand the molecular mechanism controlling rice leaf angles, one rice leaf inclination2 (lc2, three...
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Open AccessEffects of polymerase, template dilution and cycle number on PCR based 16 S rRNA diversity analysis using the deep sequencing method
The primer and amplicon length have been found to affect PCR based estimates of microbial diversity by pyrosequencing, while other PCR conditions have not been addressed using any deep sequencing method. The p...
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Open Accessβ-catenin/cyclin D1 mediated development of suture mesenchyme in calvarial morphogenesis
Mouse genetic study has demonstrated that Axin2 is essential for calvarial development and disease. Haploid deficiency of β-catenin alleviates the calvarial phenotype caused by Axin2 deficiency. This loss-of-f...
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Open AccessDeep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds
Tea is one of the most popular non-alcoholic beverages worldwide. However, the tea plant, Camellia sinensis, is difficult to culture in vitro, to transform, and has a large genome, rendering little genomic inform...
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Open AccessThe occurrence and significance of C25HBI in Cenozoic saline lacustrine source rocks from the Western Qaidam Basin, NW China
The saline lacustrine deposit of the Oligocene Lower Ganchaigou Formation is the main source rock for the Western Qaidam Basin, NW China. In this study, abundant highly branched isoprenoids with 25 carbon atom...