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  1. No Access

    Article

    Schistosoma japonicum migration through mouse skin compared histologically and immunologically with S. mansoni

    The migration of Schistosoma japonicum and S. mansoni through mouse skin epidermis and dermis was compared by immunofluorescence techniques from 4 to 22 h after infection. At all times, the percentage of parasite...

    Lin Wang, Yong-Long Li, Zvi Fishelson, John R. Kusel in Parasitology Research (2005)

  2. No Access

    Article

    Genetic Diversity and Population Differentiation of the Dominant Species Stipa krylovii in the Inner Mongolia Steppe

    Random amplified polymorphic DNA was used to assess the level of genetic diversity and genetic structure of Stipa krylovii (Gramineae), an important dominant species in the northern grasslands of China. Genetic d...

    Nian-** Zhao, Yu-Bao Gao, **-Long Wang, An-Zhi Ren in Biochemical Genetics (2006)

  3. Article

    The functional motif of SARS-CoV S protein involved in the interaction with ACE2

    SARS-CoV is a newly discovery pathogen causing severe acute respiratory problems. It has been established that the S protein in this pathogen plays an important rule in the adsorption and penetration of SARS-C...

    Yi Zhang, Wei Wang, **-rong Gao, Li Ye, **ao-nan Fang, Ying-chun Zeng in Virologica Sinica (2007)

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    Article

    A primary study of the subgroups of T lymphocytes in MHV-3 induced chronic viral hepatitis

    To study the contribution of T cell subsets in the pathogenesis of Murine hepatitis virus Type 3 (MHV-3) induced chronic viral hepatitis in C3H/Hej mice, ninety C3H/Hej mice were chosen to individually receive...

    Jiang-guo Zhang, **ao-min Qin, **ao-**g Wang, Wei-ming Yan in Virologica Sinica (2007)

  5. No Access

    Article

    Schistosoma japonicum infection modulates the development of allergen-induced airway inflammation in mice

    Asthma, a chronic inflammatory disorder of the airways, is coordinated by Th2 cells in both human asthmatics and animal models of allergic asthma. It has been shown that helminth infections including Schistosoma ...

    Hong-mei Mo, Jia-hui Lei, Zi-wei Jiang, Cheng-zu Wang, Yu-li Cheng in Parasitology Research (2008)

  6. No Access

    Article

    Variation of 423G>T in the Agouti Gene Exon 4 in Indigenous Chinese Goat Breeds

    The Agouti gene plays an important role in pigment synthesis in domestic animals. A transversion of 423G>T recognized by BanII was found after a fragment (178 bp) of the goat Agouti gene exon 4 was amplified and ...

    Chun-Juan Tang, Rong-Yan Zhou, **ang-Long Li, **g-Wen Zhao in Biochemical Genetics (2008)

  7. No Access

    Article

    Immunologic Analysis of HIV-Uninfected Taiwanese Children with BCG-Induced Disease

    The aim of this study was to evaluate immunity in HIV-uninfected children with bacille Calmette–Guerin-induced disease (BCG-ID) over an 8-year period, with particular emphasis on underlying diseases.

    Wen-I Lee, Fang-Chen Liang, **g-Long Huang in Journal of Clinical Immunology (2009)

  8. Article

    HPLC and LC-MS analysis of sinomenine and its application in pharmacokinetic studies in rats

    To improve and validate analytical methods based on HPLC and liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) for the quantitative measurement of sinomenine in r...

    Li-hong Long, Peng-fei Wu, **ang-long Chen, Zui Zhang in Acta Pharmacologica Sinica (2010)

  9. No Access

    Article

    Effect of CD4+CD25+ regulatory T cells on the immune evasion of Schistosoma japonicum

    It has been known that parasites developed sophisticated strategies to escape from the host immune assault. More recently, one strategy to induce immune evasion involved CD4+CD25+ regulatory T cells (Tregs). Mice...

    Chun-lian Tang, Jia-hui Lei, Tin Wang, Sheng-jun Lu, Fei Guan in Parasitology Research (2011)

  10. Article

    Orphan G protein-coupled receptors (GPCRs): biological functions and potential drug targets

    The superfamily of G protein-coupled receptors (GPCRs) includes at least 800 seven-transmembrane receptors that participate in diverse physiological and pathological functions. GPCRs are the most successful ta...

    **ao-long Tang, Ying Wang, Da-li Li, Jian Luo, Ming-yao Liu in Acta Pharmacologica Sinica (2012)

  11. Article

    Norisoboldine alleviates joint destruction in rats with adjuvant-induced arthritis by reducing RANKL, IL-6, PGE2, and MMP-13 expression

    To explore the effects of norisoboldine (NOR), a major isoquinoline alkaloid in Radix Linderae, on joint destruction in rats with adjuvant-induced arthritis (AIA) and its underlying mechanisms.

    Zhi-feng Wei, **ao-lan Jiao, Ting Wang, Qian Lu, Yu-feng **a in Acta Pharmacologica Sinica (2013)

  12. No Access

    Article

    Preventive effect of pidotimod on reactivated toxoplasmosis in mice

    As one of food-borne parasitic diseases, toxoplasmosis entails the risk of develo** reactivation in immunocompromised patients. The synthetic dipeptide pidotimod is a potent immunostimulating agent that impr...

    **ng-**ng Huo, Lin Wang, Zhao-Wu Chen, He Chen, **u-Cai Xu in Parasitology Research (2013)

  13. No Access

    Article

    Toxoplasma gondii infection in the peritoneal macrophages of rats treated with glucocorticoids

    It is well known that toxoplasmosis can be life threatening to immunocompromised individuals such as AIDS and organ transplantation patients. Glucocorticoids (GCs) are widely used in the clinic for the treatme...

    Tao Wang, Jiang-Mei Gao, Si-Qi Yi, Guo-Qing Geng, **ao-Jie Gao in Parasitology Research (2014)

  14. Article

    Isothiafludine, a novel non-nucleoside compound, inhibits hepatitis B virus replication through blocking pregenomic RNA encapsidation

    To investigate the action of isothiafludine (NZ-4), a derivative of bis-heterocycle tandem pairs from the natural product leucamide A, on the replication cycle of hepatitis B virus (HBV) in vitro and in vivo.

    Li Yang, Li-** Shi, Hai-jun Chen, **an-Kun Tong in Acta Pharmacologica Sinica (2014)

  15. No Access

    Article

    Isolation and full-genome sequence of two reticuloendotheliosis virus strains from mixed infections with Marek’s disease virus in China

    Reticuloendotheliosis virus (REV), classified as a gammaretrovirus, has a variety of hosts, including chickens, ducks, geese, turkeys, and wild birds. REV causes a series of pathological syndromes, especially ...

    Ke-yan Bao, Yan-** Zhang, Hui-wen Zheng, Hong-chao Lv, Yu-long Gao in Virus Genes (2015)

  16. No Access

    Article

    Molecular and pathogenicity characterization of Gallid herpesvirus 2 newly isolated in China from 2009 to 2013

    During the course of our continuous surveillance of Gallid herpesvirus 2 (GaHV-2), 44 isolates were obtained from GaHV-2-positive chickens of different flocks in China from 2009 to 2013. The meq gene, considered ...

    Yan-** Zhang, Hong-chao Lv, Ke-yan Bao, Yu-long Gao, Hong-lei Gao in Virus Genes (2016)

  17. Article

    Methylophiopogonanone A suppresses ischemia/reperfusion-induced myocardial apoptosis in mice via activating PI3K/Akt/eNOS signaling pathway

    The dried tuber root of Ophiopogon japonicus has been used in the traditional Chinese medicine for treatment of myocardial ischemia and thrombosis. In this study we investigated the effects of methylophiopogonano...

    Fei He, Bang-long Xu, Cai Chen, Hong-**g Jia, Ji-xiong Wu in Acta Pharmacologica Sinica (2016)

  18. No Access

    Article

    Can hemozoin alone cause host anaemia?

    Both schistosomes and malaria parasites produce hemozoin and cause host anaemia. However, the relationship between anaemia and hemozoin is unclear. Although some studies have proposed that hemozoin is related ...

    Jun Sun, Su-Wen Wang, Chang-Long **, **ao-Li Zeng, **ng-Yu Piao in Parasitology Research (2016)

  19. Article

    MicroRNA-1304 suppresses human non-small cell lung cancer cell growth in vitro by targeting heme oxygenase-1

    Previous studies have shown that microRNA-1304 (miR-1304) is dysregulated in certain types of cancers, including non-small cell lung cancer (NSCLC), and might be involved in tumor survival and/or growth. In th...

    Cheng-gang Li, Meng-fan Pu, Chun-zhu Li, Man Gao in Acta Pharmacologica Sinica (2017)

  20. Article

    Open Access

    Abstracts from the 8th International Congress of the Asia Pacific Society of Infection Control (APSIC)

    Nantanit Sutthiruk, Mari Botti in Antimicrobial Resistance & Infection Contr… (2017)

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