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  1. Article

    Open Access

    Altered expression patterns of lipid metabolism genes in an animal model of HCV core-related, nonobese, modest hepatic steatosis

    Because the gene expression patterns of nonobese hepatic steatosis in affected patients remain unclear, we sought to explore these patterns using an animal model of nonobese hepatic steatosis.

    Ming-Ling Chang, Chau-Ting Yeh, Jeng-Chang Chen, Chau-Chun Huang in BMC Genomics (2008)

  2. No Access

    Article

    Differential Expression of Serine/Threonine Protein Phosphatase Type-2C Under Drought Stress in Maize

    Differential display reverse transcription polymerase chain reaction was used to study the messenger RNA differential expression of a drought tolerant inbred line ‘81565’ under drought stress and well-watered ...

    Fu-Hua Li, Feng-Ling Fu, Li-Na Sha, Liang He in Plant Molecular Biology Reporter (2009)

  3. Article

    Open Access

    SnoRNAs from the filamentous fungus Neurospora crassa: structural, functional and evolutionary insights

    SnoRNAs represent an excellent model for studying the structural and functional evolution of small non-coding RNAs involved in the post-transcriptional modification machinery for rRNAs and snRNAs in eukaryotic...

    Na Liu, Zhen-Dong **ao, Chun-Hong Yu, Peng Shao, Yin-Tong Liang in BMC Genomics (2009)

  4. No Access

    Article

    Isolation and Characterization of a Temperature-Regulated Microsomal Oleate Desaturase Gene (CtFAD2-1) from Safflower (Carthamus tinctorius L.)

    A cDNA sequence, designated CtFAD2-1 and putatively encoding a delta-12 fatty acid desaturase, was isolated from total RNA of immature normal-type safflower (Carthamus tinctorius L.) seeds using a PCR approach. T...

    Ling-Liang Guan, Ying-Wen Xu, Yuan-Biao Wang, Li Chen in Plant Molecular Biology Reporter (2012)

  5. Article

    Open Access

    De novo assembly and characterization of the root transcriptome of Aegilops variabilis during an interaction with the cereal cyst nematode

    Aegilops variabilis No.1 is highly resistant to cereal cyst nematode (CCN). However, a lack of genomic information has restricted studies on CCN resistance genes in Ae. variabilis and has limited genetic applicat...

    De-Lin Xu, Hai Long, Jun-Jun Liang, Jie Zhang, **n Chen, **g-Liang Li in BMC Genomics (2012)

  6. Article

    Open Access

    Development of simple sequence repeat (SSR) markers from a genome survey of Chinese bayberry (Myrica rubra)

    Chinese bayberry (Myrica rubra Sieb. and Zucc.) is a subtropical evergreen tree originating in China. It has been cultivated in southern China for several thousand years, and annual production has reached 1.1 mil...

    Yun Jiao, Hui-min Jia, **ong-wei Li, Ming-liang Chai, Hui-juan Jia in BMC Genomics (2012)

  7. Article

    Open Access

    Global transcriptome profiles of Camellia sinensis during cold acclimation

    Tea is the most popular non-alcoholic health beverage in the world. The tea plant (Camellia sinensis (L.) O. Kuntze) needs to undergo a cold acclimation process to enhance its freezing tolerance in winter. Change...

    **n-Chao Wang, Qiong-Yi Zhao, Chun-Lei Ma, Zong-Hong Zhang, Hong-Li Cao in BMC Genomics (2013)

  8. No Access

    Article

    Sweet Preference Modified by Early Experience in Mice and the Related Molecular Modulations on the Peripheral Pathway

    The sweet taste is of immense interest to scientists and has been intensively studied during the last two decades. However, the sweet preference modification and the related mechanisms are still unclear. In th...

    Wei-Li Li, Meng-Ling Chen, Si-Si Liu, Guo-Liang Li in Journal of Molecular Neuroscience (2013)

  9. Article

    Open Access

    Exploration of microRNAs in porcine milk exosomes

    Breast milk contains complex nutrients and facilitates the maturation of various biological systems in infants. Exosomes, membranous vesicles of endocytic origin found in different body fluids such as milk, ca...

    Ting Chen, Qian-Yun **, Rui-Song Ye, **ao Cheng, Qi-En Qi, Song-Bo Wang in BMC Genomics (2014)

  10. No Access

    Article

    The PpLTP1 Primary Allergen Gene is Highly Conserved in Peach and Has Small Variations in Other Prunus Species

    Peach lipid transfer protein (LTP1), Pru p 3.01, is a major allergen causing severe systemic reactions in peach allergic patients in Mediterranean countries and China. Significant expression variability has be...

    Ying-tao Ma, **ang Zhou, Zhong-shan Gao, **ong-wei Li in Plant Molecular Biology Reporter (2014)

  11. No Access

    Article

    Double homeobox gene, Duxbl, promotes myoblast proliferation and abolishes myoblast differentiation by blocking MyoD transactivation

    Homeobox genes encode transcription factors that regulate embryonic development programs including organogenesis, axis formation and limb development. Previously, we identified and cloned a mouse double homeob...

    Shey-Lin Wu, Guo-Zili Li, Chin-Yi Chou, Ming-Shiun Tsai in Cell and Tissue Research (2014)

  12. Article

    Open Access

    Transcriptome analysis of the effect of Vibrio alginolyticus infection on the innate immunity-related complement pathway in Epinephelus coioides

    Orange-spotted grouper (Epinephelus coioides) with protogynous hermaphroditic features are one of the most economically important aquaculture species in Taiwan. However, larvae stage grouper are susceptible to in...

    Yi-Da Wang, Shin-Jie Huang, Hong-Nong Chou, Wen-Liang Liao, Hong-Yi Gong in BMC Genomics (2014)

  13. No Access

    Article

    The Anti-Aging and Tumor Suppressor Protein Klotho Enhances Differentiation of a Human Oligodendrocytic Hybrid Cell Line

    Klotho functions as an aging suppressor, which, in mice, extends lifespan when overexpressed and accelerates development of aging-like phenotypes when disrupted. Klotho is mainly expressed in brain and kidney ...

    Ci-Di Chen, Hu Li, Jennifer Liang, Kathryn Hixson in Journal of Molecular Neuroscience (2015)

  14. No Access

    Article

    Simultaneous Sensitive MEKC–LIF Determination of Homocysteine, Homoarginine, and Six Arginine Metabolic Derivatives in Fluids from Type 2 Diabetics with Peptic Ulcer Bleeding

    The suitability of micellar electrokinetic capillary chromatography (MEKC) with laser-induced fluorescence (LIF) detection for simultaneous determination of two arginine analogues (homocysteine and homoarginin...

    Qian** Liang, Hongchao Chen, Fuqing Li, **aolin Du in Chromatographia (2015)

  15. Article

    Open Access

    Transcriptome profiling reveals the genetic basis of alkalinity tolerance in wheat

    Soil alkalinity shows significant constraints to crop productivity; however, much less attention has been paid to analyze the effect of soil alkalinity on plant growth and development. Shanrong No. 4 (SR4) is ...

    Chen Meng, Tai-Yong Quan, Zhong-Yi Li, Kang-Li Cui, Li Yan, Yu Liang in BMC Genomics (2017)

  16. Article

    Open Access

    Plant miRNAs found in human circulating system provide evidences of cross kingdom RNAi

    Emerging evidence indicates that plant miRNAs can present within human circulating system through dietary intake and regulate human gene expression. Hence we deduced that comestible plants miRNAs can be identi...

    Yu-Chen Liu, Wen Liang Chen, Wei-Hsiang Kung, Hsien-Da Huang in BMC Genomics (2017)

  17. Article

    Open Access

    Function and dysfunction of plasma cells in intestine

    As the main player in humoral immunity, antibodies play indispensable roles in the body’s immune system. Plasma cells (PCs), as antibody factories, are important contributors to humoral immunity. PCs, recogniz...

    Xue Wang, Gui-liang Hao, Bo-ya Wang, Chen-chen Gao, Yue-xiu Wang in Cell & Bioscience (2019)

  18. No Access

    Article

    Kilohertz two-photon fluorescence microscopy imaging of neural activity in vivo

    Understanding information processing in the brain requires monitoring neuronal activity at high spatiotemporal resolution. Using an ultrafast two-photon fluorescence microscope empowered by all-optical laser s...

    Jianglai Wu, Yajie Liang, Shuo Chen, Ching-Lung Hsu, Mariya Chavarha in Nature Methods (2020)

  19. No Access

    Article

    Screening for functional circular RNAs using the CRISPR–Cas13 system

    Circular RNAs (circRNAs) produced from back-spliced exons are widely expressed, but individual circRNA functions remain poorly understood owing to the lack of adequate methods for distinguishing circRNAs from ...

    Siqi Li, **ang Li, Wei Xue, Lin Zhang, Liang-Zhong Yang, Shi-Meng Cao in Nature Methods (2021)

  20. No Access

    Article

    An adaptive optics module for deep tissue multiphoton imaging in vivo

    Understanding complex biological systems requires visualizing structures and processes deep within living organisms. We developed a compact adaptive optics module and incorporated it into two- and three-photon...

    Cristina Rodríguez, Anderson Chen, José A. Rivera, Manuel A. Mohr in Nature Methods (2021)

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