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1. Impact of the COVID-19 pandemic on antidepressant consumption in the Central region of Portugal: interrupted time series

   Purpose

   To evaluate the impact of the pandemic on the consumption of antidepressive agents in Central Portugal.

   Methods

   To estimate the causal effect...

   Luciana G. Negrão, Catarina Coelho, ... Fernando Fernandez-Llimos in Social Psychiatry and Psychiatric Epidemiology

   Article Open access 13 July 2024
   

2. Integrative metagenomic, transcriptomic, and proteomic analysis reveal the microbiota-host interplay in early-stage lung adenocarcinoma among non-smokers

   Background

   The incidence of early-stage lung adenocarcinoma (ES-LUAD) is steadily increasing among non-smokers. Previous research has identified...

   Yaohui Sun, Zhiming Gan, ... Qingdong Cao in Journal of Translational Medicine

   Article Open access 13 July 2024
   

3. Intricate effects of post-translational modifications in liver cancer: mechanisms to clinical applications

   Liver cancer is a significant global health challenge, with hepatocellular carcinoma (HCC) being the most prevalent form, characterized by high...

   Yu Zhang, Weihao Xu, ... Cheng Zhang in Journal of Translational Medicine

   Article Open access 13 July 2024
   

4. Lnc PVT1 facilitates TGF-β1-induced human cardiac fibroblast activation in vitro and ISO-induced myocardial fibrosis in vivo through regulating MYC

   Cardiac fibrosis is a commonly seen pathophysiological process in various cardiovascular disorders, such as coronary heart disorder, hypertension,...

   Juan Wang, Zhong-Yin Lv, ... Di-Fei Shen in Molecular and Cellular Biochemistry

   Article 13 July 2024
   

5. Rare tumours of the pancreas: monocentric study

   Purpose

   The biology of rare pancreatic tumours, which differs from that of ductal pancreatic cancer, requires increased attention. Although the...

   Astrid Bauschke, Annelore Altendorf-Hofmann, ... Utz Settmacher in Journal of Cancer Research and Clinical Oncology

   Article Open access 13 July 2024
   

6. Systematic review: genetic polymorphisms in the pharmacokinetics of high-dose methotrexate in pediatric acute lymphoblastic leukemia patients

   Variations in pharmacokinetic responses to high-dose methotrexate are essential for the prognosis and management of toxicity in the treatment of...

   Siti Utami Rahmayanti, Riezki Amalia, Taofik Rusdiana in Cancer Chemotherapy and Pharmacology

   Article 13 July 2024
   

7. Susceptibility gene mutations in germline and tumors of patients with HER2-negative advanced breast cancer

   Germline mutations in BRCA1 and BRCA2 (g BRCA1/2 ) are required for a PARP inhibitor therapy in patients with HER2-negative (HER2−) advanced breast...

   Peter A. Fasching, Chunling Hu, ... Fergus J. Couch in npj Breast Cancer

   Article Open access 13 July 2024
   

8. Reassortment incompetent live attenuated and replicon influenza vaccines provide improved protection against influenza in piglets

   Swine influenza A viruses (swIAV) cause an economically important respiratory disease in modern pig production. Continuous virus transmission and...

   Annika Graaf-Rau, Kathrin Schmies, ... Timm Harder in npj Vaccines

   Article Open access 13 July 2024
   

9. Association of low adherence to weekly cisplatin with outcomes in patients with head and neck squamous cell carcinoma: a retrospective cohort study

   Background

   The National Comprehensive Cancer Network (NCCN) guideline recommends consideration of weekly cisplatin as an alternative option for...

   Jas Virk, Jasmin Gill, ... Anurag K. Singh in BMC Cancer

   Article Open access 13 July 2024
   

10. Fluorescence Recognition of Hydrazine Driven by Neighboring Group Participation

    Hydrazine (N ₂ H ₄ ) has toxic effects on the environment. Although a variety of reactive probes have been used to identify hydrazine, practical...

    Wenzhi Xu, Xue Li, ... Wei Li in Journal of Fluorescence

    Article 13 July 2024
    

11. Cell-cell contact-dependent secretion of large-extracellular vesicles from EFNB^high cancer cells accelerates peritoneal dissemination

    Background

    Large non-apoptotic vesicles released from the plasma membrane protrusions are classified as large-EVs (LEVs). However, the triggers of LEV...

    Kaito Hayashi, Kurara Takagane, ... Masamitsu Tanaka in British Journal of Cancer

    Article 13 July 2024
    

12. Correction: MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma

    Qin Tang, Wan Li, ... Guanhua Du in Signal Transduction and Targeted Therapy

    Article Open access 13 July 2024
    

13. Benzothiazole-Quinoline-Based Fluorescent Probe for Fe³⁺ and its Applications in Environmental and Biological Samples

    Due to the its high abundance, iron ion contamination and toxicity is one of the most challenging issue for living beings. Although, iron is...

    Nidhi Nehra, Rahul Kaushik, ... Rehan Khan in Journal of Fluorescence

    Article 13 July 2024
    

14. Investigating distinct clinical features and constructing a nomogram model for survival probability in adults with cerebellar high-grade gliomas

    Background

    The clinical features of cerebellar high-grade gliomas (cHGGs) in adults have not been thoroughly explored. This large-scale,...

    Tao Chang, Rui Zhang, ... Qing Mao in BMC Cancer

    Article Open access 13 July 2024
    

15. Illuminating the Power of V₂O₅ Nanoparticles: Efficient Photocatalytic Degradation of Organic Dyes under Visible Light

    This research explores the synthesis, characterization, and application of Vanadium Pentoxide nanoparticles (V ₂ O ₅ NPs), focusing on their efficacy in...

    Sattar H. Abed, Ali H. Reshak in Journal of Fluorescence

    Article 13 July 2024
    

16. GPR116 alleviates acetaminophen-induced liver injury in mice by inhibiting endoplasmic reticulum stress

    Background

    Acetaminophen (APAP) overdose is a significant contributor to drug-induced liver injury worldwide. G-protein–coupled receptor 116 (GPR116)...

    Qian **ang, Na Li, ... **jun Bian in Cellular and Molecular Life Sciences

    Article Open access 13 July 2024
    

17. Targeting CERS6-AS1/FGFR1 axis as synthetic vulnerability to constrain stromal cells supported proliferation in Mantle cell lymphoma

    The interaction between stromal and tumor cells in tumor microenvironment is a crucial factor in Mantle cell lymphoma (MCL) progression and therapy...

    Udita **dal, Mukesh Mamgain, ... Neeraj Jain in Leukemia

    Article 13 July 2024
    

18. Replacement of sedentary behavior with various physical activities and the risk of incident depression: a prospective analysis of accelerator-measured and self-reported UK Biobank data

    Purpose

    To examine the dose‒response relationships of sedentary behavior (SB) and physical activities (PAs) with depression, and to explore the...

    Jia-Hui Zhu, Zhen-Zhen Shen, ... Cun-**an Jia in Social Psychiatry and Psychiatric Epidemiology

    Article 13 July 2024
    

19. CCT6A promotes cell proliferation in colon cancer by targeting BIRC5 associated with p53 status

    Chaperonin-containing TCP1 (CCT) is a multi-subunit complex, known to participate the correct folding of many proteins. Currently, the mechanism...

    Han Zhang, Taotao Zheng, ... Huawen Liu in Cancer Gene Therapy

    Article 13 July 2024
    

20. Re-administration of platinum-based chemotherapy for recurrent endometrial cancer: an ancillary analysis of the SGSG-012/GOTIC-004/Intergroup study

    Background

    We previously demonstrated the applicability of the concept of “platinum sensitivity” in recurrent endometrial cancer. Although immune...

    Shoji Nagao, Shin Nishio, ... Hisashi Masuyama in International Journal of Clinical Oncology

    Article Open access 13 July 2024