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Article
IL-17 response mediates acute lung injury induced by the 2009 Pandemic Influenza A (H1N1) Virus
The 2009 flu pandemic involved the emergence of a new strain of a swine-origin H1N1 influenza virus (S-OIV H1N1) that infected almost every country in the world. Most infections resulted in respiratory illness...
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Article
Open AccessIL-10 signaling in CD4+ T cells is critical for the pathogenesis of collagen-induced arthritis
IL-10 is a very important anti-inflammatory cytokine. However, the role of this cytokine in T cells in the pathogenesis of collagen-induced arthritis is unclear. The purpose of this study was to define the rol...
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Article
Current progress in γδ T-cell biology
T lymphocytes bearing γ- and δ-chain T-cell receptor heterodimers are named γδ T cells. Interestingly, γδ and αβ T cells share the same progenitors, and they undergo a fate decision in the thymus. Functional d...
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Article
Active hexose correlated compound enhances tumor surveillance through regulating both innate and adaptive immune responses
Active hexose correlated compound (AHCC) is a mixture of polysaccharides, amino acids, lipids and minerals derived from cocultured mycelia of several species of Basidiomycete mushrooms. AHCC has been implicate...
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Article
Resistance to Development of Collagen-Induced Arthritis in C57BL/6 Mice Is Due to a Defect in Secondary, but Not in Primary, Immune Response
Collagen-induced arthritis (CIA) is a rodent model of human rheumatoid arthritis. Mice of the H-2q (DBA/1J) background are highly susceptible to disease whereas mice of the H-2b (C57BL/6, B6) background are resis...
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Article
γδ T cells in autoimmunity
γδ T cells likely play a critical role in the host defenses, and recent evidence has indicated they are important in regulation of the immune response after pathogen challenge. Data are also accumulating that ...
