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Article
Open AccessFoods contributing to nutrients intake and assessment of nutritional status in pre-dialysis patients: a cross-sectional study
For chronic kidney disease (CKD) patients, management of nutritional status is critical for delaying progression to end-stage renal disease. The purpose of this study is to provide the basis for personalized n...
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Article
Open AccessAggregation and Cellular Toxicity of Pathogenic or Non-pathogenic Proteins
More than 20 unique diseases such as diabetes, Alzheimer’s disease, Parkinson’s disease are caused by the abnormal aggregations of pathogenic proteins such as amylin, β-amyloid (Aβ), and α-synuclein. All patho...
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Chapter and Conference Paper
Real Time 3D Pose Estimation of Both Human Hands via RGB-Depth Camera and Deep Convolutional Neural Networks
3D human hand pose estimation (HPE) is an essential methodology for smart human computer interfaces. Especially, 3D hand pose estimation without attached or hand-held sensors provides a more natural and conven...
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Article
Open AccessRemoval of large middle molecules via haemodialysis with medium cut-off membranes at lower blood flow rates: an observational prospective study
Online haemodiafiltration (OL-HDF) may improve middle molecular clearance in contrast to conventional haemodialysis (HD). However, OL-HDF requires higher convective flows and cannot sufficiently remove large m...
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Article
Phase field simulations of coupled microstructure solidification problems via the strong form particle difference method
This paper presents the development of a strong form-based collocation method called the particle difference method (PDM), capable of predicting the spatiotemporal evolution of polycrystalline material solidif...
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Article
Open AccessDevelopment of a PMMA phantom as a practical alternative for quality control of gamma knife® dosimetry
To measure the absorbed dose rate to water and penumbra of a Gamma Knife® (GK) using a polymethyl metacrylate (PMMA) phantom.
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Article
Phenolics and eudesmanolide from aged common sage exudate with sugar
Nineteen compounds including one new flavanone were isolated from the juice of aged common sage exudate with sugar (ACSE). The isolated compounds were identified by NMR and MS analyses as levodopa methyl ester (1
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Article
EXAFS Characterization of Pd Catalysts for Enantioselective Hydrogenation of α-Phenylcinnamic Acid: Pretreatment Effects and Thiol Adsorption
The effects of the pretreatment and Pd-distribution on the enantioselective hydrogenation of α-phenylcinnamic acid over cinchonidine-modified Pd/C and Pd/Al2O3 were studied by use of EXAFS techniques combined wit...
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Article
Error Analysis of a B-Spline Based Finite-Element Method for Modeling Wind-Driven Ocean Circulation
We present the results of an error analysis of a B-spline based finite-element approximation of the stream-function formulation of the large scale wind-driven ocean circulation. In particular, we derive optima...
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Article
Optimization of diphtheria toxin production by Corynebacterium diphtheriae using a casein-based medium in a fermenter
The Td-based combined vaccine contains only small amounts of the diphtheria toxoid antigen. However, a high level of purity is necessary for this antigen. The diphtheria toxin is produced by growing Corynebacteri...
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Article
Tetanus toxin production from Clostridium tetani, using a casein-based medium in a single-use bioreactor
Clostridium tetani, a spore-forming anaerobic bacterium, and a casein-based semisynthetic medium were used to produce tetanus toxin in this study. N-Z-Case TT (casein hydrolysate)...
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Article
Wound healing effect of visible light-curable chitosan with encapsulated EGF
Low molecular O-carboxymethyl chitosan, a derivative of chitosan, was conjugated with a hydrophilic carboxymethyl group, following which the conjugate was modified with a furfuryl group. The chitosan derivativ...
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Article
Improved resistance against oxidative stress of engineered cellobiose-fermenting Saccharomyces cerevisiae revealed by metabolite profiling
Cellobiose has garnered attention as an alternative carbon source for numerous biotechnological processes because it is produced when lignocellulosic biomass is treated with endo and exo-glucanases. An enginee...
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Article
History and Evolution of Surgical Ethics: John Gregory to the Twenty-first Century
As surgery grew to become a respected medical profession in the eighteenth century, medical ethics emerged as a response to the growing need to protect patients and maintain the public’s trust in physicians. T...
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Article
Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression
Mammalian target of rapamycin (mTOR) is an attractive target for cancer treatment. While rapamycin and its derivatives (e.g., everolimus) have been shown to inhibit mTOR signaling and cell proliferation in pre...
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Article
Enantioselective Hydrogenation of Olefins using Commercially Available Pd/C. Chiral Heterogeneous Catalyst Applicable for High-Throughput Screening
Cinchonidine-modified Pd/C applicable for the high-throughput-guided study was developed. Commercial Pd/C catalysts were employed for the enantioselective hydrogenation of phenylcinnamic acid after the pretrea...
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Article
Conditioning of Palladium-on-carbon (Pd/C) for Uniform Cinchonidine Modification to Perform Highly Enantioselective Hydrogenation
Cinchonidine (CD)-modified palladium catalyst gave the high product ee when a commercial wet Pd/C was used after the co-evaporation pretreatment. The improvement in the ee was attributed to removal of water fr...
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Article
Enantioselective Hydrogenation in Water Over Chiral Modified Heterogeneous Catalyst Admixed With Organic Solvent
Hydrogenation of α,β-unsaturated acid over cinchonidine-modified Pd/C results in poor enantioselectivity in water, but the selectivity becomes much higher when Pd/C is admixed with a small amount of a hydrophobic...
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Article
A mortared finite element method for frictional contact on arbitrary interfaces
This work concerns finite-element algorithms for imposing frictional contact constraints on intra-element, or embedded surfaces. Existing techniques typically rely on the underlying bulk mesh to implicitly par...
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Article
Gentiobiose synthesis from glucose using recombinant β-glucosidase fromThermus caldophilus GK24
Recombinant β-glucosidase fromThermus caldophilus GK24 was easily purified partially by a heat treatment procedure, resulting in 8-fold and recovery yield of 80% from crude enzyme. When the β-glucosidase was incu...
