1,297 Result(s)
within
Ming-**u Li
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessHydrogen peroxide is required for light-induced stomatal opening across different plant species
Stomatal movement is vital for plants to exchange gases and adaption to terrestrial habitats, which is regulated by environmental and phytohormonal signals. Here, we demonstrate that hydrogen peroxide (H2O2) is r...
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Open AccessAnalytical and experimental analysis of concrete temperature and energy considering open-air environmental variations
Longwave radiation is an important open-air environmental factor that can significantly affect the temperature of concrete, but it has often been ignored in the temperature analysis of open-air concrete struct...
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Open AccessMidbrain glutamatergic circuit mechanism of resilience to socially transferred allodynia in male mice
The potential brain mechanism underlying resilience to socially transferred allodynia remains unknown. Here, we utilize a well-established socially transferred allodynia paradigm to segregate male mice into pa...
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Open AccessDevelopment of deaminase-free T-to-S base editor and C-to-G base editor by engineered human uracil DNA glycosylase
DNA base editors enable direct editing of adenine (A), cytosine (C), or guanine (G), but there is no base editor for direct thymine (T) editing currently. Here we develop two deaminase-free glycosylase-based b...
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Open AccessBacteroidetes promotes esophageal squamous carcinoma invasion and metastasis through LPS-mediated TLR4/Myd88/NF-κB pathway and inflammatory changes
Gut microbiota plays a crucial role in gastrointestinal tumors. Additionally, gut microbes influence the progression of esophageal cancer. However, the major bacterial genera that affect the invasion and metas...
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Open AccessEfficient intersystem crossing and tunable ultralong organic room-temperature phosphorescence via do** polyvinylpyrrolidone with polyaromatic hydrocarbons
Polymer-based pure organic room-temperature phosphorescent materials have tremendous advantages in applications owing to their low cost, vast resources, and easy processability. However, designing polymer-base...
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Open AccessAplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
Pathologic α-synuclein (α-syn) spreads from cell-to-cell, in part, through binding to the lymphocyte-activation gene 3 (Lag3). Here we report that amyloid β precursor-like protein 1 (Aplp1) interacts with Lag3...
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Open AccessDomain wall magnetic tunnel junction-based artificial synapses and neurons for all-spin neuromorphic hardware
We report a breakthrough in the hardware implementation of energy-efficient all-spin synapse and neuron devices for highly scalable integrated neuromorphic circuits. Our work demonstrates the successful execut...
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Open AccessHMG-CoA reductase is a potential therapeutic target for migraine: a mendelian randomization study
Statins are thought to have positive effects on migraine but existing data are inconclusive. We aimed to evaluate the causal effect of such drugs on migraines using Mendelian randomization. We used four types ...
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Open AccessDeciphering anoikis resistance and identifying prognostic biomarkers in clear cell renal cell carcinoma epithelial cells
This study tackles the persistent prognostic and management challenges of clear cell renal cell carcinoma (ccRCC), despite advancements in multimodal therapies. Focusing on anoikis, a critical form of programm...
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Open AccessRemarkable flexibility in freestanding single-crystalline antiferroelectric PbZrO3 membranes
The ultrahigh flexibility and elasticity achieved in freestanding single-crystalline ferroelectric oxide membranes have attracted much attention recently. However, for antiferroelectric oxides, the flexibility...
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Open AccessFiring feature-driven neural circuits with scalable memristive neurons for robotic obstacle avoidance
Neural circuits with specific structures and diverse neuronal firing features are the foundation for supporting intelligent tasks in biology and are regarded as the driver for catalyzing next-generation artifi...
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Open AccessGanoderma tsuage promotes pain sensitivity in aging mice
Advances in modern medicine have extended human life expectancy, leading to a world with a gradually aging society. Aging refers to a natural decline in the physiological functions of a species over time, such...
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Article
Open AccessOsMAPK6 phosphorylation and CLG1 ubiquitylation of GW6a non-additively enhance rice grain size through stabilization of the substrate
The chromatin modifier GRAIN WEIGHT 6a (GW6a) enhances rice grain size and yield. However, little is known about its gene network determining grain size. Here, we report that MITOGEN-ACTIVED PROTEIN KINASE 6 (...
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Article
Open AccessTwo telomere-to-telomere gapless genomes reveal insights into Capsicum evolution and capsaicinoid biosynthesis
Chili pepper (Capsicum) is known for its unique fruit pungency due to the presence of capsaicinoids. The evolutionary history of capsaicinoid biosynthesis and the mechanism of their tissue specificity remain obsc...
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Open AccessApplication of a hybrid algorithm of LSTM and Transformer based on random search optimization for improving rainfall-runoff simulation
Flood forecasting using traditional physical hydrology models requires consideration of multiple complex physical processes including the spatio-temporal distribution of rainfall, the spatial heterogeneity of ...
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Article
Open AccessSingle-zinc vacancy unlocks high-rate H2O2 electrosynthesis from mixed dioxygen beyond Le Chatelier principle
Le Chatelier’s principle is a basic rule in textbook defining the correlations of reaction activities and specific system parameters (like concentrations), serving as the guideline for regulating chemical/cata...
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Open AccessFirefly-inspired bipolar information indication system actuated by white light
The indication of information in materials is widely used in our daily life, and optical encoding materials are ideal for information loading due to their easily readable nature and adjustable optical properti...
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Open AccessA time-resolved multi-omics atlas of transcriptional regulation in response to high-altitude hypoxia across whole-body tissues
High-altitude hypoxia acclimatization requires whole-body physiological regulation in highland immigrants, but the underlying genetic mechanism has not been clarified. Here we use sheep as an animal model for ...
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Open AccessPD-1/CD80+ small extracellular vesicles from immunocytes induce cold tumours featured with enhanced adaptive immunosuppression
Only a minority of cancer patients benefit from immune checkpoint blockade therapy. Sophisticated cross-talk among different immune checkpoint pathways as well as interaction pattern of immune checkpoint molec...
