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  1. No Access

    Article

    Factors influencing haemopoietic recovery following chemotherapy-mobilised autologous peripheral blood progenitor cell transplantation for haematological malignancies: a retrospective analysis of a 10-year single institution experience

    We retrospectively analysed the factors that influenced rate of haemopoietic recovery (HR) in 243 patients after transplantation with chemotherapy-mobilised autologous peripheral blood progenitor cells (PBPC)....

    RM Lowenthal, C Fabères, G Marit, JM Boiron, P Cony-Makhoul… in Bone Marrow Transplantation (1998)

  2. No Access

    Article

    Factors affecting both peripheral blood progenitor cell mobilization and hematopoietic recovery following autologous blood progenitor cell transplantation in multiple myeloma patients: a monocentric study

    The aim of the study was to analyze the factors influencing peripheral blood progenitor cell (PBPC) collection after high-dose cyclophosphamide (HDCYC) (7 g/m2) and hematopoietic recovery after autologous transpl...

    G Marit, F Thiessard, C Faberes, P Cony-Makhoul, JM Boiron, P Bernard… in Leukemia (1998)

  3. No Access

    Article

    Endothelial cell support of hematopoiesis is differentially altered by IL-1 and glucocorticoids

    We investigated the ability of endothelial cells (EC) to support hematopoiesis in contact and non-contact cocultures with isolated CD34+ or CD34+/CD38low cells. In the absence of exogenous cytokines, umbilical ve...

    B Jazwiec, A Solanilla, C Grosset, F-X Mahon, M Dupouy, V Pigeonnier-Lagarde… in Leukemia (1998)

  4. No Access

    Chapter and Conference Paper

    Early Allogeneic Transplantation Favorably Influences the Outcome of Adult Patients Suffering from Acute Myeloid Leukemia

    Allogeneic BMT for patients with acute myeloid leukemia (AML) is presently a reference therapy. The indications for this therapy may likely rely upon prognostic factors, and their importance are constantly inv...

    E. Jourdan, D. Maraninchi, J. Reiffers, E. Gluckman, B. Rio… in Acute Leukemias VII (1998)

  5. No Access

    Chapter and Conference Paper

    Blood Stem Cell Transplantation in Acute Myeloid Leukemia

    Autologous blood cell transplantation (BCT) is an alternative to autologous bone marrow transplantation (BMT) for patients with acute myeloid leukemia (AML) in first remission. Its main advantage is that it is...

    J. Reiffers in Acute Leukemias VII (1998)

  6. No Access

    Article

    Flow cytometry CD45 gating for immunophenoty** of acute myeloid leukemia

    A flow cytometry method has been introduced into the routine investigation of whole bone marrow samples following red blood cell lysis on the basis of a primary CD45/side scatter (SSC) gating procedure. Blast ...

    F Lacombe, F Durrieu, A Briais, P Dumain, F Belloc, E Bascans, J Reiffers… in Leukemia (1997)

  7. No Access

    Article

    Long-term results after allogeneic bone marrow transplantation for chronic myelogenous leukemia in chronic phase: a report from the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation

    The purpose of this study was to determine the long-term results of allogeneic bone marrow transplantation for chronic myeloid leukemia. A retrospective analysis was carried out of the outcome of 373 consecuti...

    F van Rhee, RM Szydlo, J Hermans, A Devergie, F Frassoni… in Bone Marrow Transplantation (1997)

  8. No Access

    Article

    European results of matched unrelated donor bone marrow transplantation for chronic myeloid leukemia. Impact of HLA class II matching

    We have retrospectively analyzed the impact of prognostic factors on the outcome of serologically HLA-matched unrelated donor (UD) BMT for CML. For this purpose, we have studied a cohort of 366 patients transp...

    A Devergie, JF Apperley, M Labopin, A Madrigal, N Jacobsen… in Bone Marrow Transplantation (1997)

  9. No Access

    Article

    All-trans retinoic acid potentiates the inhibitory effects of interferon α on chronic myeloid leukemia progenitors in vitro

    All-trans retinoic acid (ATRA) has recently been shown to synergise with the inhibitory effect of interferon alpha (IFNα) on the growth of malignant cells isolated from solid tumors. We investigated whether ATRA ...

    FX Mahon, H Chahine, C Barbot, V Pigeonnier, B Jazwiec, J Reiffers, J Ripoche in Leukemia (1997)

  10. No Access

    Article

    Early allogeneic transplantation favorably influences the outcome of adult patients suffering from acute myeloid leukemia

    Allogeneic BMT for patients with acute myeloid leukemia (AML) is presently a reference therapy. The indications for this therapy mainly rely upon prognostic factors, and their importance is constantly reassess...

    E Jourdan, D Maraninchi, J Reiffers, E Gluckman, B Rio… in Bone Marrow Transplantation (1997)

  11. No Access

    Article

    Allogeneic bone marrow transplantation for acute leukemia in patients over the age of 40 years

    Extension of allogeneic transplants to older patients has been limited by a high risk of transplant-related death and graft-versus-host disease. To evaluate the feasibility in older patients, a retrospective a...

    J-Y Cahn, M Labopin, A Schattenberg, J Reiffers, R Willemze, R Zittoun… in Leukemia (1997)

  12. No Access

    Article

    Plasma cytokines in graft vs host disease and complications following bone marrow transplantation

    A cohort of 201 autologous or allogeneic bone marrow transplanted (BMT) patients were included for studying the evolution of circulating tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6) by mean...

    A. N. Abdallah, J. M. Boiron, Y. Attia, A. Cassaigne… in Hematology and Cell Therapy (1997)

  13. No Access

    Chapter and Conference Paper

    Peripheral Blood Stem Cell Transplantation in Acute Myeloid Leukemia

    Autologous peripheral blood stem cell (PBSC) transplantation was first successfully performed in patients with acute myelogenous leukemia (AML) during the mid 1980s. Since these reports [1-3], the number of pa...

    J. Reiffers, J.-M. Boiron, P. Cony-Makhoul, G. Marit, F.-X. Mahon… in Acute Leukemias VI (1997)

  14. No Access

    Chapter and Conference Paper

    Allogeneic and Autologous Bone Marrow Transplantation and Chemotherapy in First Remission of Adult Acute Lymphoblastic Leukemia: Results of the LALA 87 Trial of the French Group

    In a prospective study of 317 acute lymphoblastic leukemia (ALL) patients aged 15–40 years and in complete remission, 257 had a potential donor and one HLA ty** analysis; A total of 116 patients were allocat...

    D. Fière, J. P. Vernant, J. Reiffers, J. M. Miclea, F. Witz… in Acute Leukemias VI (1997)

  15. No Access

    Article

    Blood cell transplantation: past, present and future

    Blood cell transplantation is rapidly replacing bone marrow transplantation for restoration of hematopoiesis after high-dose chemotherapy in both the autologous and allogeneic settings. Future developments of ...

    J. M. Boiron, J. Reiffers, R. M. Lowenthal in Hematology and Cell Therapy (1996)

  16. No Access

    Article

    Correction of the enzyme deficit of bone marrow cells in congenital erythropoietic porphyria by retroviral gene transfer

    F. Moreau-Gaudry, C. Barbot, F. Mazurier, F. X. Mahon… in Hematology and Cell Therapy (1996)

  17. No Access

    Chapter and Conference Paper

    Recombinant Human Erythropoietin After Bone Marrow Transplantation — A Placebo Controlled Trial

    Several historically controlled studies [1,3,5] and one small open prospective randomized trial [4] showed an acceleration of erythropoietic recon-stitution after allogeneic bone marrow transplantation (BMT). ...

    H. Link, M. A. Boogaerts, A. Fauser, R. Or, J. Reiffers, N. C. Gorin… in Acute Leukemias V (1996)

  18. No Access

    Chapter and Conference Paper

    IL2 in Acute Leukemia

    Immunotherapy is a logical approach for the strategy of a currative treatment for acute leukemia since allogeneic bone marrow transplantation had demonstrated the benefit of graft versus host disease (GVHD) to...

    D. Blaise, A. M. Stoppa, M. Attal, J. Reiffers, J. Fleury… in Acute Leukemias V (1996)

  19. No Access

    Chapter and Conference Paper

    Bone Marrow Transplantation for Chronic Myeloid Leukemia in France. Results of the French Cooperative Group

    Transplants were performed in 281 patients (pts) with chronic myeloid leukemia (CML) in France between 1979 and 1986. The actuarial survival after 5 years is 55% for the patients receiving grafts in first chro...

    A. Devergie, J. Reiffers, J. P. Vernant, P. Hérvé, D. Guyotat, D. Maraninchi… in Leukemias (1993)

  20. No Access

    Chapter

    The Use of Long-Term Culture Techniques to Study Peripheral Blood Stem Cells Before and After Autologous Transplantation

    Autologous blood stem cells collected during the recovery phase after intensive chemotherapy are rich in progenitor cells, and, when infused into patients who have received myeloablative therapy, lead to rapid...

    A. Rice, C. Foures, P. Bernard, G. Marit… in Peripheral Blood Stem Cell Autografts (1993)

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