54 Result(s)

Article

Double-hit lymphomas and complex variant translocations of t(14;18)(q32;q21.3)

Masayuki Kato, Ikuo Miura in Annals of Hematology (2013)

Article

Comparative chromosome map** of sex-linked genes and identification of sex chromosomal rearrangements in the Japanese wrinkled frog (Rana rugosa, Ranidae) with ZW and XY sex chromosome systems

There are regional variations of sex chromosome morphologies in the Japanese wrinkled frog, Rana rugosa (2n = 26): heterogametic ZZ/ZW-type and XX/XY-type sex chromosomes, and two different types of homomorphic s...

Yoshinobu Uno, Chizuko Nishida, Yuki Oshima, Satoshi Yokoyama… in Chromosome Research (2008)

Article

Close relation between 14q32/IGH translocations and chromosome 13 abnormalities in multiple myeloma: a high incidence of 11q13/CCND1 and 16q23/MAF

Many B-cell tumors have chromosomal translocations that result from failures of the immunoglobulin (Ig) gene during V(D)J recombination, somatic hypermutation (SHM), and class switch recombination (CSR). Nearl...

Madoka Takimoto, Kohei Ogawa, Yo Kato, Tasuku Saito… in International Journal of Hematology (2008)

Article

The t(1;3)(p34;q27)translocation: a nonrandom BCL6 rearrangement in diffuse large B cell lymphoma

Nozomi Niitsu, Hirokazu Nakamine, Yuki Hagiwara, Ken Tanae… in Annals of Hematology (2008)

Article

A case of acute myeloblastic leukemia with a novel variant of t(8;21)(q22;q22)

We encountered a case of acute myeloblastic leukemia (AML), with extramedullary leukemia (EML) and a masked type of the variant translocation t(8;21)(q22;q22). Morphologically, the AML M2 subtype according to ...

Keiki Kawakami, Kazuhiro Nishii, Ryuu Hyou… in International Journal of Hematology (2008)

Article

t(6;14)(q15;q32) in a Patient with CD5+CD10+ Diffuse Large B-Cell Lymphoma

A 68-year-old man presented with systemic lymph node swelling. A biopsy specimen taken from the right cervical lymph node showed that the normal architecture was replaced by a diffuse proliferation of large ly...

Miyuki Hayama, Nozomi Niitsu, Masaaki Higashihara… in International Journal of Hematology (2007)

Article

Nationwide Survey of Hemophagocytic Lymphohistiocytosis in Japan

Hemophagocytic lymphohistiocytosis (HLH), a disorder of the mononuclear phagocyte system, can be classified into two distinct forms: primary HLH (FHL) and secondary HLH. To clarify the epidemiology and clinica...

Eiichi Ishii, Shouichi Ohga, Shinsaku Imashuku… in International Journal of Hematology (2007)

Article

Acute Myelomonocytic Leukemia with Dysplastic Bone Marrow Eosinophils Showing t(5;17)(q13;q11) and a Secondary Chromosomal Aberration, inv(16)(p13q22)

inv(16)(p13q22) is associated with de novo acute myelomonocytic leukemia with dysplastic bone marrow eosinophils (AMML Eo), which has a relatively favorable clinical course with a longer remission duration and...

Rika Sakai, Katsumichi Fujimaki, Etsuko Yamazaki… in International Journal of Hematology (2006)

Article

Multicenter phase II study of the CyclOBEAP (CHOP-like + etoposide and bleomycin) regimen for patients with poor-prognosis aggressive lymphoma

Our aim was to study the efficacy of the addition of etoposide and bleomycin to a [cyclophosphamide (CPA), doxorubicin (DXR), vincristine (VCR), and prednisone (PDN)] CHOP-like regimen for the treatment of agg...

Nozomi Niitsu, Masataka Okamoto, Sadao Aoki, Hirokazu Okumura… in Annals of Hematology (2006)

Article

An XX/XY sex microchromosome system in a freshwater turtle, Chelodina longicollis (Testudines: Chelidae) with genetic sex determination

Heteromorphic sex chromosomes are rare in turtles, having been described in only four species. Like many turtle species, the Australian freshwater turtle Chelodina longicollis has genetic sex determination, but n...

Tariq Ezaz, Nicole Valenzuela, Frank Grützner, Ikuo Miura… in Chromosome Research (2006)

Article

Successful Reduced-Intensity Hematopoietic Stem Cell Transplantation in Myelodysplastic Syndrome with Severe Coronary Artery Disease

A 60-year-old Japanese man with myelodysplastic syndrome (MDS) and effort angina was referred to our clinic for treatment of MDS.The patient was transfusion-dependent and displayed coronary artery disease (CAD...

Shigeki Kosugi, Makoto Hirokawa, Yoshinari Kawabata… in International Journal of Hematology (2006)

Article

The dragon lizard Pogona vitticeps has ZZ/ZW micro-sex chromosomes

The bearded dragon, Pogona vitticeps (Agamidae: Reptilia) is an agamid lizard endemic to Australia. Like crocodilians and many turtles, temperature-dependent sex determination (TSD) is common in agamid lizards, a...

Tariq Ezaz, Alexander E. Quinn, Ikuo Miura, Stephen D. Sarre… in Chromosome Research (2005)

Article

Implementation of the modified-SHIRPA protocol for screening of dominant phenotypes in a large-scale ENU mutagenesis program

SHIRPA is a three-stage protocol for the comprehensive assessment of primarily mouse behavior. The first stage consists of high-throughput phenoty** of 33 behavioral observations and 7 metabolic or disease o...

Hiroshi Masuya, Maki Inoue, Yumiko Wada, Aya Shimizu, Junko Nagano… in Mammalian Genome (2005)

Article

Fluorescence In Situ Hybridization Monitoring of BCR-ABL-Positive Neutrophils in Chronic-Phase Chronic Myeloid Leukemia Patients during the Primary Stage of Imatinib Mesylate Therapy

We describe a method for monitoring chronic myeloid leukemia (CML) patients treated with imatinib that uses fluorescence in situ hybridization (FISH) to detect BCR- ABL in peripheral blood (PB) granulocytes. Firs...

Naoto Takahashi, Ikuo Miura, Yoshimi Kobayashi… in International Journal of Hematology (2005)