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Chapter
Pijn bij kinderen
Pijn bij kinderen kan gaan over pasgeborenen die een hielprik ondergaan tot adolescenten met migraine. Uit de gevalsbeschrijvingen blijkt ook hoe belangrijk de context is waarin pijn optreedt en hoe ieder kind...
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Article
Het kortedarmsyndroom
In 1987 publiceerden Tibboel en Affourtit in dit tijdschrift een overzichtsartikel over het kortedarmsyndroom bij kinderen. Zij concludeerden dat er na neonatale darmresectie een ernstige morbiditeit optreedt ...
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Article
Evaluatie van resterende darmfunctie in de dagelijkse praktijk
When the digestive and absorptive capacity of the gastrointestinal tract are insufficient, as they are in patients with short bowel syndrome (sbs), systematic evaluation of the remaining gut function is of the ut...
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Article
Nieuwe ontwikkelingen in de behandeling van het kortedarmsyndroom bij kinderen
Short bowel syndrome is characterized by malabsorption of nutrients, vitamins en trace elements, resulting in growth retardation. Children with short bowel syndrome are often dependent on total parenteral nutr...
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Article
Het kortedarmsyndroom bij kinderen
Patients with short bowel syndrome suffer from malabsorption due to loss of functional intestinal mass. The incidence is not exactly known since many different definitions of the syndrome have been reported. T...
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Article
Complicatieregistratie in de kindergeneeskundige praktijk
Complication registration is a major instrument for improving quality of healthcare. It may serve, first, to determine frequency and severity of complications, and next how to reduce incidences and severities.
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Chapter and Conference Paper
Patient Safety Management System in Pediatric ICUs
The multidisciplinary approach of the project is improving patient safety by continuous quality assessment and modification guided by monthly, real data. Cost effectiveness of patient safety management systems...
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Chapter and Conference Paper
Patient Safety Management System in Pediatric ICUs
Patient safety has become an increasingly important topic of discussion in health care organizations all over the world. The publication of the report To err is human by the Institute of Medicine in the United St...
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Article
O-demethylation of tramadol in the first months of life
Assess in vivo O-demethylation activity in the first months of life.
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Article
The Critically Ill Adults scale
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Article
Tramadol concentrations in blood and in cerebrospinal fluid in a neonate
Based on blood and cerebrospinal fluid samples collected in a full-term neonate, the penetration of tramadol in the central nervous system is described. Following intravenous administration of tramadol, a lag ...
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Article
Genetics and developmental biology of oesophageal atresia and tracheo-oesophageal fistula: lessons from mice relevant for paediatric surgeons
Oesophageal atresia and tracheo-oesophageal fistula are relatively frequently occurring foregut malformations of which the aetiology and pathogenesis are poorly understood. Recent results of molecular genetic ...
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Article
7 Ontogeny of Udp-Glucuronosyltransferase Activity During Repeated Administration of Propacetamol in Neonates
Background: Major changes in drug clearance are observed during infancy, at least partially based on ontogenic regulation of metabolic pathways but data on maturation of UDP-glucuronosyltransferase (UGT)-activity...
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Article
276 Neonates With Severe Respiratory Insufficiency Requiring ECMO Have Decreased Surfactant Synthesis
Background: Respiratory insufficiency in neonates with congenital diaphragmatic hernia (CDH), meconium aspiration syndrome (MAS) or other forms of persistent pulmonary hypertensin of the newborn (PPHN) is frequen...
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Article
6 Impact of Administration of Analgesics During Neonatal Stay on Pain Expression Following Neonatal Stay in Former Preterm Infants
Introduction: There are still few data on the impact of pharmacologic treatment of pain during neonatal stay in preterm infants on pain expression after neonatal stay. We therefore investigated pain expression in...
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Article
Acetaminophen in cerebrospinal fluid in children
There are few studies describing acetaminophen (APAP) cerebrospinal fluid (CSF) concentrations in children. This current study was undertaken in children—from neonates to adolescents—in order to investigate ag...
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Article
Pijnmeting en pijnbehandeling: hoe verder?
Following the development of more than thirty instruments for pain assessment in the last ten years, there is a need for implementation of well validated instruments. In this way pain assessment will be part o...
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Article
Postoperatieve pijnbestrijding
Against the background of contemporary knowledge of nociception, the appropriate use of analgetic drugs following major surgery is described. The consequences of age dependent differences in the socalled hormo...
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Article
Tracheal Ligation and Corticosteroids in Congenital Diaphragmatic Hernia: For Better for Worse?
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Article
“Gut-feeling” or evidence-based approaches in the evaluation and treatment of human short-bowel syndrome
Short bowel syndrome is the malabsorptive state that often follows extensive resection of the small intestine. Long-term survival without parenteral nutrition depends on the process of intestinal adaptation, ...
