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Article
Expression of Early Immune Response Genes during Physical Exercise
Study by means of expression profiling with Human GeneChip ST1.0 microchips (Affymetrix) revealed 10 early immune response genes, whose expression was modified after short-term intense physical exercise. They ...
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Article
Cross Effect of Electrostimulation of Quadriceps Femoris Muscle during Maximum Voluntary Contraction under Conditions of Biofeedback
We describe cross effect of enhancement of muscular power and electrical activity during electrical stimulation. Due to the use of electrostimulation method with biological feedback and effort visualization fo...
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Article
The human thermal portrait and its relations with aerobic working capacity and the blood lactate level
In a study on 53 healthy male volunteers with the use of an infrared thermograph, data that the thermal portrait, i.e., skin temperature distribution, under the conditions of muscular rest and minimal chemical...
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Article
Expression profiling and putative mechanisms of resistance to doxorubicin of human lung cancer cells
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Article
Prediction of Epitopes in Closely Related Proteins Using a New Algorithm
Latrophilin 1 (presynaptic receptor) binds α-latrotoxin from black widow spider venom and regulates neurotransmitter release from nerve endings. The study of the mechanism of action of this receptor is impeded...
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Article
Application of Mid-Infrared Molecular Spectroscopy for Assessment of Biochemical Parameters of Blood Serum
The method of mid-infrared molecular spectroscopy allows precise measuring of the concentrations of a large number of biological molecules in a minimal sample volume. Method of projections on latent structures...
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Article
Peculiarities of Brain Information Processing in Persons with Different Serotonin Transporter Gene Variants
Association of brain processes presumably underlying aggression with serotonin transporter gene polymorphism in men was studied. Carriers of more active gene variant are characterized by higher aggression inde...
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Article
Effect of a Six-Hour Marathon Ultra-Race on the Levels of IL-6, LIF, and SCF
The effects of 6-h marathon ultra-race (long aerobic work below the lactate threshold level) on the levels of IL-6, leukemia inhibiting factor (LIF), and stem cell growth factor (SCF) were studied. The athlete...
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Article
Assessment of Biochemical Characteristics of the Saliva Using Fourier Transform Mid-Infrared Spectroscopy
We developed a method of rapid assay for biochemical properties of the saliva based on attenuated total reflection infrared spectroscopy. This method allows evaluating saliva composition within 5 min without s...
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Article
Studying the Copy Number of Ribosomal Protein L7/L12
Studying the copy number of ribosomal protein L7/L12 was performed using monoclonal antibody 3G9 to the linear epitope on the C-terminal domain of this protein from Escherichia coli. Immunohistochemical study sho...
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Article
Gender Effects on Association of Serotonin Transporter Gene Polymorphism with Symptoms of Central Fatigue
In order to test the “serotonin” hypothesis of the genesis of central fatigue, we studied association between genotype and fatigue (3-hour mental workload consisting of information processing and logical task ...
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Article
Prediction of linear B-cell epitopes
The use of antigenicity scales based on physicochemical properties and the sliding window method in combination with an averaging algorithm and subsequent search for the maximum value is the classical method f...
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Article
Genetic Markers of Predisposition to Increased Anxiety
Associations of functional polymorphism in genes of dopamine receptor DRD2, dopamine transporter DAT, and dopamine degrading enzyme COMT with variations in anxiety sensitivity threshold were studied. On the ba...
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Article
Modulation of cardiac rhythm in the humans exposed to extremely weak alternating magnetic fields
The effect of extremely weak alternating magnetic fields of various types with the amplitudes δ of 2 μT on the heart rate variability in humans was studied. Volunteers were placed in a large-volume coil system...
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Article
Relationship between the Degree of Cardiovascular Adaptation and Th1/Th2 Polarization of Immune Response
The main parameters of humoral immunity during medium intensity exercise were studied in oarsmen with high and low cardiovascular adaptation. A relationship between high cardiovascular adaptation to exercise a...
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Article
Analysis of Major Isoforms of Human Growth Hormone before and after Intensive Physical Exercise
We developed a semiquantitative method for the analysis of main growth hormone isoforms. The use of immunoaffinity sorbents, two-dimensional electrophoresis, and immunoblotting allows detection of more than 90...
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Article
The origin of eubacteria with three L7/L12 protein dimers in the ribosome
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Article
Free testosterone as marker of adaptation to medium-intensive exercise
A 4-week study of adaptation reserves of the body was carried out during medium intensive exercise (medium intensive training: 60–80% threshold anaerobic metabolism). Two groups of athletes were singled out by...
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Article
Prospects of studying the polymorphisms of key genes of neurotransmitter systems: II. The serotonergic system
The review deals with the genetic principles of personality features that are helpful in both efficient athlete selection and improved training. The variations of the genes of the serotonergic system, associat...
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Article
Role of renin-angiotensin system in the formation of emotional state in humans
We studied the effect of angiotensin-converting enzyme gene polymorphism on human emotional state in humans (189 athletes and 212 volunteers not engaged in sport activity). The distribution of angiotensin-conv...
