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Article
Causal Bayesian gene networks associated with bone, brain and lung metastasis of breast cancer
Using a machine learning method, this study aimed to identify unique causal networks of genes associated with bone, brain, and lung metastasis of breast cancer. Bayesian network analysis identified differentia...
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Article
Adolescent dairy product and calcium intake in relation to later prostate cancer risk and mortality in the NIH-AARP Diet and Health Study
Although a growing body of evidence supports an early-life contribution to prostate cancer (PCa) development, few studies have investigated early-life diet, and only three have examined early-life dairy produc...
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Article
Low serum cholesterol as a risk factor for kidney and bladder cancer among Korean men: using a national cohort sample
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Article
Benign gynecologic conditions are associated with ovarian cancer risk in African-American women: a case–control study
The association between common benign gynecologic conditions and ovarian cancer remains under-studied in African Americans. Therefore, we examine the association between self-reported history of benign gynecol...
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Article
Childhood diet and growth in boys in relation to timing of puberty and adult height: the Longitudinal Studies of Child Health and Development
To begin to explore the possible roles of childhood diet and growth in prostate cancer (PCa) development, we investigated these exposures in relation to two known/suspected PCa risk factors, earlier pubertal t...
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Article
Open AccessCXCR4 can induce PI3Kδ inhibitor resistance in ABC DLBCL
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Open AccessAbstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers
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Open AccessValidation of response assessment according to international consortium for MDS/MPN criteria in chronic myelomonocytic leukemia treated with hypomethylating agents
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Open AccessDiscrepancies between the percentage of plasma cells in bone marrow aspiration and BM biopsy: Impact on the revised IMWG diagnostic criteria of multiple myeloma
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Article
Helicobacter pylori infection is an independent risk factor for colonic adenomatous neoplasms
Helicobacter pylori infection is considered to have a positive association with colorectal neoplasms. In this study, we evaluated the association between H. pylori infection and colore...
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Article
Open AccessBone marrow stromal cells show distinct gene expression patterns depending on symptomatically involved organs in multiple myeloma
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Open AccessAnti-myeloma activity of MELK inhibitor OTS167: effects on drug-resistant myeloma cells and putative myeloma stem cell replenishment of malignant plasma cells
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Article
Diagnostic colonoscopy following a positive fecal occult blood test in community health center patients
Fecal occult blood testing (FOBT) is a pragmatic screening option for many community health centers (CHCs), but FOBT screening programs will not reduce mortality if patients with positive results do not underg...
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Article
Effect of bexarotene on differentiation of glioblastoma multiforme compared with ATRA
Glioblastoma multiforme (GBM) is the most aggressive malignant brain tumor. Since differentiation can attenuate or halt the growth of tumor cells, an image-based phenotypic screening was performed to find out ...
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Article
Oncogenic role of SIRT1 associated with tumor invasion, lymph node metastasis, and poor disease-free survival in triple negative breast cancer
The aim of this study is to evaluate the biological role and clinical implications of silent mating type information regulation 2 homolog 1 (SIRT1) as a novel candidate for target therapy in triple negative br...
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Article
Open AccessSignificance of KIT exon 17 mutation depends on mutant level rather than positivity in core-binding factor acute myeloid leukemia
KIT exon 17 mutation is a poor prognostic factor in core-binding factor acute myeloid leukemia. However, the mutation detection method used for risk assessment is not assigned. It is necessary to verify the analy...
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Article
Open AccessThe effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium
Epidemiological studies suggest a potential role for obesity and determinants of adult stature in prostate cancer risk and mortality, but the relationships described in the literature are complex. To address u...
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Article
Open AccessSingle monosomy as a relatively better survival factor in acute myeloid leukemia patients with monosomal karyotype
Monosomal karyotype (MK) defined by either ⩾2 autosomal monosomies or single monosomy with at least one additional structural chromosomal abnormality is associated with a dismal prognosis in patients with acut...
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Article
Racial/ethnic differences in lifestyle-related factors and prostate cancer risk: the Multiethnic Cohort Study
Older age, African ancestry, and family history of prostate cancer are well-established risk factors for prostate cancer, and all are non-modifiable. Various lifestyle factors have been examined in relation to...
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Article
Open AccessComparison between pre-operative MRI and intra-operative endoscopic findings for idiopathic normal pressure hydrocephalus