33 Result(s)

Article

Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway

Mesenchymal stem cell (MSC)-derived exosomes emerge as promising candidates for treating delayed wound healing in diabetes due to the promotion of angiogenesis. Preconditioned MSC with chemical or biological f...

Muyu Yu, Wei Liu, Junxian Li, Junxi Lu, Huijuan Lu… in Stem Cell Research & Therapy (2020)

Article

Enhanced therapeutic effects of umbilical cord mesenchymal stem cells after prolonged treatment for HBV-related liver failure and liver cirrhosis

Umbilical cord mesenchymal stem cells (UCMSCs) have been demonstrated to have good therapeutic effects in the treatment of HBV-related liver diseases. However, the therapeutic effect of UCMSCs on HBV-related l...

Yifan Jia, **n Shu, **aoan Yang, Haixia Sun, Huijuan Cao… in Stem Cell Research & Therapy (2020)

Article

Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation

Tuberous sclerosis complex (TSC) is characterized by hamartomatous lesions in multiple organs, with most patients develo** polycystic kidney disease and leading to a decline of renal function. TSC is caused ...

Yili Fang, Fang Li, Chenyang Qi, **ng Mao, Feng Wang, Zhonghua Zhao… in Cell Death Discovery (2020)

Article

Neutrophil extracellular traps induced by VP1 contribute to pulmonary edema during EV71 infection

Pulmonary edema is a fatal complication of EV71-associated hand, foot, and mouth disease (HFMD). The pathogenesis of EV71-induced pulmonary edema remains largely unclear. In this study, we aimed to explore the...

Nan Wang, **aofan Yang, Jiandong Sun, Zhixiao Sun, Qiyun Ma… in Cell Death Discovery (2019)

Article

Identification of small non-coding RNAs as sperm quality biomarkers for in vitro fertilization

Minmin Hua, Wei Liu, Ying Chen, Fengjuan Zhang, Beiying Xu, Suying Liu… in Cell Discovery (2019)

Article

Author Correction: CRISPR–Cas9-mediated base-editing screening in mice identifies DND1 amino acids that are critical for primordial germ cell development

In Fig. 2a of this Technical Report originally published, the authors inadvertently used the same set of images for the 4B2N1 and 4B2N3 cells when preparing the figure. The three images (bright field, Oct4-EGF...

Qing Li, Yan**g Li, Suming Yang, Shuo Huang, Meng Yan, Yifu Ding… in Nature Cell Biology (2019)

Article

Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target

Qingqing Zhang, Huijuan Liu, **ang Liu, Dunquan Jiang, Bingjie Zhang… in Protein & Cell (2018)

Article

Mesenchymal stem cells and extracellular matrix scaffold promote muscle regeneration by synergistically regulating macrophage polarization toward the M2 phenotype

Skeletal muscle plays an important role in the body’s physiology but there are still no effective treatments for volumetric muscle loss (VML) resulting from severe traumatic injury or tumor excision. Recent st...

**nyu Qiu, Shiyu Liu, Hao Zhang, Bin Zhu, Yuting Su… in Stem Cell Research & Therapy (2018)

Article

TP53TG1 enhances cisplatin sensitivity of non-small cell lung cancer cells through regulating miR-18a/PTEN axis

The acquisition of drug resistance has been considered as a main obstacle for cancer chemotherapy. Tumor protein 53 target gene 1 (TP53TG1), a p53-induced lncRNA, plays a vital role in the progression of human...

Huijuan **ao, Yihe Liu, Pan Liang, Bo Wang, Hongna Tan, Yonggao Zhang… in Cell & Bioscience (2018)

Article

Long non-coding RNA CASC2 improved acute lung injury by regulating miR-144-3p/AQP1 axis to reduce lung epithelial cell apoptosis

Apoptosis of lung epithelial cell is implicated in the pathogenesis of acute lung injury (ALI). To study the protective effect and mechanism of cancer susceptibility candidate 2 (CASC2) on reducing lung epithe...

Hongbin Li, Huijuan Shi, Min Gao, Ning Ma, Rongqing Sun in Cell & Bioscience (2018)