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  1. No Access

    Article

    Sodium removal per ultrafiltration volume in automated peritoneal dialysis in pediatric patients

    The standard rate of sodium removal in adult anuric patients on continuous ambulatory peritoneal dialysis (CAPD) is 7.5 g/L of ultrafiltration volume (UFV). Although automated PD (APD) is widely used in pediat...

    Takashi Tokunaga, Riku Hamada, Tomohiro Inoguchi, Chikako Terano in Pediatric Nephrology (2024)

  2. Article

    Open Access

    The Japanese Breast Cancer Society Clinical Practice Guidelines for Breast Cancer, 2022 Edition: changes from the 2018 edition and general statements on breast cancer treatment

    The Japanese Breast Cancer Society Clinical Practice Guidelines for Breast Cancer, 2022 Edition was published in June 2022. The guidelines were prepared while conforming as much as possible to the “Minds Manua...

    Yutaka Yamamoto, Chikako Yamauchi, Tatsuya Toyama, Shigenori Nagai in Breast Cancer (2024)

  3. No Access

    Article

    Early endpoints of a randomized phase II trial of preoperative chemotherapy with S-1/CDDP with or without trastuzumab followed by surgery for HER2-positive resectable gastric or esophagogastric junction adenocarcinoma with extensive lymph node metastasis: Japan Clinical Oncology Group study JCOG1301C (Trigger Study)

    This randomized phase II study explored the superiority of trastuzumab plus S-1 plus cisplatin (SP) over SP alone as neoadjuvant chemotherapy (NAC) for HER2-positive resectable gastric cancer with extensive ly...

    Masanori Tokunaga, Nozomu Machida, Junki Mizusawa, Seiji Ito in Gastric Cancer (2024)

  4. No Access

    Article

    No clear influence of treatment escalation on flare prevention in serologically active clinically quiescent patients with systemic lupus erythematosus: a retrospective cohort study

    This study aimed to clarify the efficacy and safety of treatment escalation by initiating therapeutic agents in serologically active clinically quiescent (SACQ) patients with systemic lupus erythematosus (SLE)...

    Masahiro Ayano, Akie Hirata, Shoji Tokunaga, Hiroko Furuhashi in Rheumatology International (2024)

  5. No Access

    Article

    Inguinal hernia repair in patients with artificial urinary sphincter after radical prostatectomy

    Stress urinary incontinence (UI) often develops after radical prostatectomy for prostate cancer, and in those patients with moderate-to-severe stress UI an artificial urinary sphincter (AUS) is implanted. Ingu...

    Y. Yatabe, T. Tanioka, Y. Waseda, K. Yamaguchi, T. Ogo, H. Fujiwara, K. Okuno in Hernia (2024)

  6. Article

    Open Access

    A novel NODAL variant in a young embolic stroke patient with visceral heterotaxy

    Ischemic stroke in young adults can be caused by a variety of etiologies including the monogenic disorders. Visceral heterotaxy is a condition caused by abnormal left–right determinations during embryonic deve...

    Kei Kaburagi, Yuta Hagiwara, Keiji Tachikawa, Noriko Miyake in BMC Neurology (2024)

  7. Article

    Open Access

    Comparison of complications of intrascleral fixation according to the extent of vitrectomy

    Intraocular lens (IOL) fixation is performed after intraoperative anterior or total vitrectomy. This study aimed to compare the intraoperative and postoperative complications of these two techniques.

    Miho Yamada, Eiichi Nishimura, Sayako Watanabe, Masanori Yoshino in BMC Ophthalmology (2024)

  8. Article

    Open Access

    Graphical user interface-based convolutional neural network models for detecting nasopalatine duct cysts using panoramic radiography

    Nasopalatine duct cysts are difficult to detect on panoramic radiographs due to obstructive shadows and are often overlooked. Therefore, sensitive detection using panoramic radiography is clinically important....

    Kotaro Ito, Naohisa Hirahara, Hirotaka Muraoka, Eri Sawada in Scientific Reports (2024)

  9. No Access

    Article

    Texture analysis using short-tau inversion recovery magnetic resonance images to differentiate squamous cell carcinoma of the gingiva from medication-related osteonecrosis of the jaw

    Despite the difficulty in distinguishing between squamous cell carcinoma (SCC) and medication-related osteonecrosis of the jaw (MRONJ) on the basis of medical imaging examinations, the two conditions have comp...

    Kotaro Ito, Naohisa Hirahara, Hirotaka Muraoka, Eri Sawada in Oral Radiology (2024)

  10. No Access

    Article

    Comparison of the short-term surgical outcomes of lateral lymph node dissection for low rectal cancer using a robotic-assisted transabdominal approach alone or supported by a transanal approach

    Lateral lymph node metastases are a major cause of local recurrence after surgery for advanced low rectal cancer. Lateral lymph node dissection (LLND) may reduce the risk of local recurrence in patients with s...

    Takuya Tokunaga, Hideya Kashihara, Kozo Yoshikawa, Toshihiro Nakao in Surgical Endoscopy (2024)

  11. No Access

    Article

    Effect of the Cooling Capability Difference Between Additively Manufactured Sand Molds on Shrinkage Defect in A356 Alloy Castings

    Three-dimensional sand mold printing is a novel manufacturing method that can produce complicated shapes based on a 3D CAD model. Various types of material systems can be employed to produce 3D-printed sand mo...

    Yuichi Motoyama, Hitoshi Tokunaga in International Journal of Metalcasting (2024)

  12. No Access

    Article

    The hypothetical molecular mechanism of the ethnic variations in the manifestation of age-related macular degeneration; focuses on the functions of the most significant susceptibility genes

    Age-related macular degeneration (AMD) is the leading sight-threatening disease in developed countries. On the other hand, recent studies indicated an ethnic variation in the phenotype of AMD. For example, sev...

    Shigeru Honda, Norihiko Misawa, Yusuke Sato in Graefe's Archive for Clinical and Experime… (2024)

  13. Article

    Open Access

    Fulminant myocarditis during postoperative adjuvant chemotherapy for lung cancer with atezolizumab: a case report

    Postoperative adjuvant systemic therapy with atezolizumab for lung cancer has been reported to be effective. Although myocarditis is a rare immune adverse event associated with atezolizumab, it can have a seri...

    Takuya Tokunaga, Masaya Aoki, Koki Maruyama, Yuto Nonaka in Journal of Medical Case Reports (2024)

  14. Article

    Open Access

    Observation of nonvolatile magneto-thermal switching in superconductors

    Applying a magnetic field to a solid changes its thermal-transport properties. Although such magneto-thermal-transport phenomena are usually small effects, giant magneto-thermal resistance has recently been ob...

    Hiroto Arima, Md. Riad Kasem, Hossein Sepehri-Amin, Fuyuki Ando in Communications Materials (2024)

  15. Article

    Open Access

    Peculiar magnetotransport properties in epitaxially stabilized orthorhombic Ru3+ perovskite LaRuO3 and NdRuO3

    Complex oxides are interesting materials where multiple physical properties and functionalities can be realized by integrating different elements in a single compound. However, owing to the chemical instabilit...

    Lingfei Zhang, Takahiro C. Fujita, Yuuki Masutake in Communications Materials (2024)

  16. Article

    Open Access

    Alteration of serotonin release response in the central nucleus of the amygdala to noxious and non-noxious mechanical stimulation in a neuropathic pain model rat

    Previously, we found that serotonin (5-HT) release in the central nucleus of the amygdala (CeA) of anesthetized rats decreases in response to innocuous stroking of the skin, irrespective of stimulus laterality...

    Ryota Tokunaga, Hideshi Shibata, Mieko Kurosawa in The Journal of Physiological Sciences (2024)

  17. No Access

    Article

    Effects of a force feedback function in a surgical robot on the suturing procedure

    Currently, widely used robotic surgical systems do not provide force feedback. This study aimed to evaluate the impact and benefits of a force feedback function on the suturing procedure.

    Yoshimi Yamasaki, Masanori Tokunaga, Yoshihiro Sakai, Hiroki Kayasuga in Surgical Endoscopy (2024)

  18. Article

    Open Access

    Preoperative evaluation to determine the difficulty of No. 6 lymphadenectomy in laparoscopic gastrectomy

    Laparoscopic gastrectomy (LG) requires a long learning curve because of the complicated surgical procedures. Infrapyloric (No. 6) lymph node dissection (LND) is one of the difficult procedures in LG, especiall...

    Chie Takasu, Masaaki Nishi, Kozo Yoshikawa, Takuya Tokunaga in BMC Surgery (2024)

  19. Article

    Open Access

    Assessing the efficacy of target adaptive sampling long-read sequencing through hereditary cancer patient genomes

    Innovations in sequencing technology have led to the discovery of novel mutations that cause inherited diseases. However, many patients with suspected genetic diseases remain undiagnosed. Long-read sequencing ...

    Wataru Nakamura, Makoto Hirata, Satoyo Oda, Kenichi Chiba, Ai Okada in npj Genomic Medicine (2024)

  20. Article

    Open Access

    Association between comorbidities associated with diabetes and higher-level functional status in older patients with type 2 diabetes mellitus: a cross sectional study

    To investigate the association between comorbidities associated with diabetes and higher-level functional status in older patients with type 2 diabetes mellitus.

    Takuro Shoji, Kenta Kogure, Nagisa Toda, Mariko Hakoshima in European Geriatric Medicine (2024)

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