148 Result(s)
within
English
Science, Humanities and Social Sciences, multidisciplinary
Science, Humanities and Social Sciences, multidisciplinary
Li-**n Tao
Article
-
Article
Open AccessTumor necrosis factor-α G-308A (rs1800629) polymorphism and aggressive periodontitis susceptibility: a meta-analysis of 16 case-control studies
Association between tumor necrosis factor-α (TNF-α) G-308A (rs1800629) polymorphism and susceptibility to aggressive periodontitis (AgP) were inconsistent, hence we performed this meta-analysis to clarify the ...
-
Article
Open AccessCoupling of soil prokaryotic diversity and plant diversity across latitudinal forest ecosystems
The belowground soil prokaryotic community plays a cardinal role in sustaining the stability and functions of forest ecosystems. Yet, the nature of how soil prokaryotic diversity co-varies with aboveground pla...
-
Article
Open AccessGenome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference
Sixty genetic loci associated with abdominal obesity, measured by waist circumference (WC) and waist-hip ratio (WHR), have been previously identified, primarily from studies conducted in European-ancestry popu...
-
Article
Open AccessLimited Antigenic Diversity in Contemporary H7 Avian-Origin Influenza A Viruses from North America
Subtype H7 avian–origin influenza A viruses (AIVs) have caused at least 500 confirmed human infections since 2003 and culling of >75 million birds in recent years. Here we antigenically and genetically charact...
-
Article
Open AccessUnraveling and engineering the production of 23,24-bisnorcholenic steroids in sterol metabolism
The catabolism of sterols in mycobacteria is highly important due to its close relevance in the pathogenesis of pathogenic strains and the biotechnological applications of nonpathogenic strains for steroid syn...
-
Article
Open AccessNovel loci and pathways significantly associated with longevity
Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated ...
-
Article
Open AccessFunctioning free gracilis transfer to reconstruct elbow flexion and quality of life in global brachial plexus injured patients
In the study, the functional recovery and relative comprehensive quality of life of cases of global brachial plexus treated with free functioning muscle transfers were investigated. Patients who received funct...
-
Article
Open AccessInter-molecular β-sheet structure facilitates lung-targeting siRNA delivery
Size-dependent passive targeting based on the characteristics of tissues is a basic mechanism of drug delivery. While the nanometer-sized particles are efficiently captured by the liver and spleen, the micron-...
-
Article
Open AccessAmino Compounds as Inhibitors of De Novo Synthesis of Chlorobenzenes
The inhibitory effects of four amino compounds on the formation of chlorobenzenes (CBzs) - dioxin precursors and indicators, and the inhibitory mechanisms were explored. The results show NH4H2PO4 can decrease the...
-
Article
Open AccessNewcastle disease virus NP and P proteins induce autophagy via the endoplasmic reticulum stress-related unfolded protein response
Newcastle disease virus (NDV) can replicate and trigger autophagy in human tumor cells. Our previous study confirmed the critical role of autophagy in NDV infection. Here we studied the role of NDV structural ...
-
Article
Open AccessCXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment
White adipose tissue (WAT) overgrowth in obesity is linked with increased aggressiveness of certain cancers. Adipose stromal cells (ASCs) can become mobilized from WAT, recruited by tumours and promote cancer ...
-
Article
Open AccessPharmacological inhibition of MyD88 homodimerization counteracts renal ischemia reperfusion-induced progressive renal injury in vivo and in vitro
The activation of innate immunity via myeloid differentiation factor 88 (MyD88) contributes to ischemia reperfusion (I/R) induced acute kidney injury (AKI) and chronic kidney injury. However, since there have ...
-
Article
Open AccessIn vivo Monitoring of Serotonin by Nanomaterial Functionalized Acupuncture Needle
Acupuncture treatment is amazing but controversial. Up to now, the mechanism of treating diseases by acupuncture and moxibustion is still unclear, especially the occurrence of the molecular events in local acu...
-
Article
Open AccessEvolutionary trajectories of snake genes and genomes revealed by comparative analyses of five-pacer viper
Snakes have numerous features distinctive from other tetrapods and a rich history of genome evolution that is still obscure. Here, we report the high-quality genome of the five-pacer viper, Deinagkistrodon acutus
-
Article
Open AccessOptimal Universal Uncertainty Relations
We study universal uncertainty relations and present a method called joint probability distribution diagram to improve the majorization bounds constructed independently in [Phys. Rev. Lett. 111, 230401 (2013)] an...
-
Article
Open AccessDiagnostic Value and Surgical Implications of the 3D DW-SSFP MRI On the Management of Patients with Brachial Plexus Injuries
Three-dimensional diffusion-weighted steady-state free precession (3D DW-SSFP) of high-resolution magnetic resonance has emerged as a promising method to visualize the peripheral nerves. In this study, the app...
-
Article
Open AccessAnalysis of codon usage patterns in Ginkgo biloba reveals codon usage tendency from A/U-ending to G/C-ending
As one of the most ancient tree species, the codon usage pattern analysis of Ginkgo biloba is a useful way to understand its evolutionary and genetic mechanisms. Several studies have been conducted on angiosperms...
-
Article
Open AccessEnhancing succinic acid biosynthesis in Escherichia coli by engineering its global transcription factor, catabolite repressor/activator (Cra)
This study was initiated to improve E. coli succinate production by engineering the E. coli global transcription factor, Cra (catabolite repressor/activator). Random mutagenesis libraries were generated through e...
-
Article
Open AccessIntegrative mutation, haplotype and G × G interaction evidence connects ABGL4, LRP8 and PCSK9 genes to cardiometabolic risk
This study is expected to investigate the association of ATP/GTP binding protein-like 4 (AGBL4), LDL receptor related protein 8 (LRP8) and proprotein convertase subtilisin/kexin type 9 (PCSK9) gene single nucl...
-
Article
Open AccessTMED3 promotes hepatocellular carcinoma progression via IL-11/STAT3 signaling
Transmembrane p24 trafficking protein 3(TMED3) is a metastatic suppressor in colon cancer, but its function in the progression of hepatocellular carcinoma (HCC) is unknown. Here, we report that TMED3 was up-re...
