80 Result(s)

Article

Transcriptomic analysis reveals biosynthesis genes and transcription factors related to leaf anthocyanin biosynthesis in Aglaonema commutatum

Aglaonema commutatum ‘Red Valentine’, as a foliage ornamental plant, is widely used for interior and exterior decoration because of its easy cultivation and management. However, reduced proportion of red foliage ...

Ji Li, Kunlin Wu, Lin Li, Guohua Ma, Lin Fang, Songjun Zeng in BMC Genomics (2023)

Article

Gene expressions between obligate bamboo-eating pandas and non-herbivorous mammals reveal converged specialized bamboo diet adaptation

It is inevitable to change the function or expression of genes during the environmental adaption of species. Both the giant panda (Ailuropoda melanoleuca) and red panda (Ailurus fulgens) belong to Carnivora and h...

**nan Ma, Liang Zhang, Fujun Shen, Yang Geng, Yan Huang, Honglin Wu… in BMC Genomics (2023)

Article

A TNFR1–UBCH10 axis drives lung squamous cell carcinoma dedifferentiation and metastasis through a cell-autonomous signaling loop

Tumor necrosis factor receptor 1 (TNFR1), encoded by TNFRSF1A, is a critical transducer of inflammatory pathways, but its physiological role in human cancer is not completely understood. Here, we observed high ex...

Zuoxiang **ao, Gong** Shi, Sichuan **, Amit Kumar Singh… in Cell Death & Disease (2022)

Article

ABAT gene expression associated with the sensitivity of hypomethylating agents in myelodysplastic syndrome through CXCR4/mTOR signaling

The factors that affect hypomethylating agents (HMAs) sensitivity in myelodysplastic syndrome (MDS) are complex and multifaceted. They include DNA methylation, gene expression, mutation, etc. However, the unde...

Guangjie Zhao, Shuang Li, Qian Wang, Wanlin Wu, Xuewei Fu, Chen Zhu… in Cell Death Discovery (2022)

Article

TREM2/β-catenin attenuates NLRP3 inflammasome-mediated macrophage pyroptosis to promote bacterial clearance of pyogenic bacteria

Triggering receptors expressed on myeloid cells 2 (TREM2) is considered a protective factor to protect host from bacterial infection, while how it elicits this role is unclear. In the present study, we demonst...

Yi Wang, Can Cao, Yanting Zhu, Huifeng Fan, Qiaojuan Liu… in Cell Death & Disease (2022)

Article

Mitochondrial PKM2 deacetylation by procyanidin B2-induced SIRT3 upregulation alleviates lung ischemia/reperfusion injury

Apoptosis is a critical event in the pathogenesis of lung ischemia/reperfusion (I/R) injury. Sirtuin 3 (SIRT3), an important deacetylase predominantly localized in mitochondria, regulates diverse physiological...

**g Zhao, Guorong Wang, Kaitao Han, Yang Wang, Lin Wang… in Cell Death & Disease (2022)

Article

Acute cannabinoids impair association learning via selectively enhancing synaptic transmission in striatonigral neurons

Cannabinoids and their derivatives attract strong interest due to the tremendous potential of their psychoactive effects for treating psychiatric disorders and symptoms. However, their clinical application is ...

Meilin Wu, Yuanyuan Di, Zhijun Diao, Chuanting Yan, Qiangqiang Cheng… in BMC Biology (2022)

Article

Genomes of leafy and leafless Platanthera orchids illuminate the evolution of mycoheterotrophy

To improve our understanding of the origin and evolution of mycoheterotrophic plants, we here present the chromosome-scale genome assemblies of two sibling orchid species: partially mycoheterotrophic Platanthera ...

Ming-He Li, Ke-Wei Liu, Zhen Li, Hsiang-Chia Lu, Qin-Liang Ye… in Nature Plants (2022)

Article

Integration of adeno-associated virus (AAV) into the genomes of most Thai and Mongolian liver cancer patients does not induce oncogenesis

Engineered versions of adeno-associated virus (AAV) are commonly used in gene therapy but evidence revealing a potential oncogenic role of natural AAV in hepatocellular carcinoma (HCC) has raised concerns. The...

Alejandro A. Schäffer, Dana A. Dominguez, Lesley M. Chapman… in BMC Genomics (2021)

Article

Characterization of phytohormone and transcriptome profiles during protocorm-like bodies development of Paphiopedilum

Paphiopedilum, commonly known as slipper orchid, is an important genus of orchid family with prominent horticultural value. Compared with conventional methods such as tillers and in vitro shoots multiplication, i...

Beiyi Guo, Songjun Zeng, Yuying Yin, Lin Li, Guohua Ma, Kunlin Wu, Lin Fang in BMC Genomics (2021)

Article

Loss of ID3 drives papillary thyroid cancer metastasis by targeting E47-mediated epithelial to mesenchymal transition

Papillary thyroid cancer (PTC) is the main histological type of thyroid cancer and accounts for almost all increased cases worldwide. Patients with PTC exhibit a favorable prognosis, but the fact that PTC is o...

Sunwang Xu, Caiqin Mo, Junyu Lin, Yixing Yan, **aoyu Liu, Kunlin Wu… in Cell Death Discovery (2021)

Article

Wolfberry genomes and the evolution of Lycium (Solanaceae)

Wolfberry Lycium, an economically important genus of the Solanaceae family, contains approximately 80 species and shows a fragmented distribution pattern among the Northern and Southern Hemispheres. Although seve...

You-Long Cao, Yan-long Li, Yun-Fang Fan, Zhen Li, Kouki Yoshida… in Communications Biology (2021)

Article

Correction to: Shifting the microbiome of a coral holobiont and improving host physiology by inoculation with a potentially beneficial bacterial consortium

Ying Zhang, Qingsong Yang, Juan Ling, Lijuan Long, Hui Huang… in BMC Microbiology (2021)

Article

Genome-scale profiling of circulating cell-free DNA signatures for early detection of hepatocellular carcinoma in cirrhotic patients

Lei Chen, Ghassan K. Abou-Alfa, Bo Zheng, **g-Feng Liu, Jian Bai… in Cell Research (2021)

Article

Shifting the microbiome of a coral holobiont and improving host physiology by inoculation with a potentially beneficial bacterial consortium

The coral microbiome plays a key role in host health by being involved in energy metabolism, nutrient cycling, and immune system formation. Inoculating coral with beneficial bacterial consortia may enhance the...

Ying Zhang, Qingsong Yang, Juan Ling, Lijuan Long, Hui Huang… in BMC Microbiology (2021)

Article

Isolation and genomic characterization of five novel strains of Erysipelotrichaceae from commercial pigs

Members of the Erysipelotrichaceae family have a high abundance in the intestinal tract of mammals, and have been reported to be associated with host metabolic disorders and inflammatory diseases. In our previ...

**yuan Wu, Min Liu, Mengqing Zhou, Lin Wu, Hui Yang, Lusheng Huang… in BMC Microbiology (2021)

Article

Correction to: An analytical pipeline for identifying and map** the integration sites of HIV and other retroviruses

An amendment to this paper has been published and can be accessed via the original article.

Daria W. Wells, Shuang Guo, Wei Shao, Michael J. Bale, John M. Coffin… in BMC Genomics (2020)

Article

Transcriptome analysis provides insights into the non-methylated lignin synthesis in Paphiopedilum armeniacum seed

Paphiopedilum is an important genus of the orchid family Orchidaceae and has high horticultural value. The wild populations are under threat of extinction because of overcollection and habitat destruction. Mature...

Lin Fang, **n Xu, Ji Li, Feng Zheng, Mingzhi Li, **gwei Yan, Yuan Li… in BMC Genomics (2020)