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Homozygous 11p15-p14 Deletion Syndrome
Homozygous 11p15-p14 deletion syndrome was first reported in 2000 by Maria Bitner-Glindzicz et al. in members of two consanguineous families who...
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Elongin B promotes breast cancer progression by ubiquitinating tumor suppressor p14/ARF
AbstractElongin B (ELOB), a pivotal element in the ELOB/c-Cullin2/5-SOCS-box E3 ubiquitin-protein ligase complex, plays a significant role in...
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Structural Characterization and Functional Studies of Exopolysaccharide by Native Lacticaseibacillus rhamnosus P14 Isolated from the Moroccan Region
Exopolysaccharides (EPS) are natural polymers synthesized by several microorganisms, including lactic acid bacteria (LAB). They are characterized by...
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Assessment of the ability of Meyerozyma guilliermondii P14 to produce second-generation bioethanol from giant reed (Arundo donax) biomass
The present study was aimed to evaluate the ability of Meyerozyma guilliermondii P14 to produce bioethanol from pretreated biomass of giant reed ( Arun...
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CRL2-KLHDC3 E3 ubiquitin ligase complex suppresses ferroptosis through promoting p14ARF degradation
The cystine/glutamate antiporter SLC7A11 (commonly known as xCT) functions to import cystine for glutathione biosynthesis, thereby protecting cells...
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Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the receptor protein of CRL2Prame complex
Protein Preferentially Expressed Antigen in Melanoma (Prame), a tumor-associated antigen, has been found to frequently overexpress in various...
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Farnesoid X receptor functions in cervical cancer via the p14ARF-mouse double minute 2-p53 pathway
BackgroundCervical cancer is the second most common cancer among women living in develo** countries. Farnesoid X receptor (FXR) is a member of the...
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Fusogenic vesicular stomatitis virus combined with natural killer T cell immunotherapy controls metastatic breast cancer
BackgroundMetastatic breast cancer is a leading cause of cancer death in woman. Current treatment options are often associated with adverse side...
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Characterization of Retinal VIP-Amacrine Cell Development During the Critical Period
Retinal vasoactive intestinal peptide amacrine cells (VIP-ACs) play an important role in various retinal light-mediated pathological processes...
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Genes and novel sRNAs involved in PAHs degradation in marine bacteria Rhodococcus sp. P14 revealed by the genome and transcriptome analysis
Rhodococcus sp. P14 is able to degrade various polycyclic aromatic hydrocarbons (PAHs). In this study, 6 ring-hydroxylating dioxygenases and 24...
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Metallic groundwater contamination assessment using the heavy metal pollution index: a case study of the Guelma plain alluvial groundwater, Northeast of Algeria
Groundwater contamination is a serious problem at the local and international levels. It can be influenced by both natural and anthropogenic factors....
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Determinants of p14/ARF methylation in healthy females: association with reproductive and non-reproductive risk factors of breast cancer
BackgroundDNA methylation is associated with the risk factors of breast cancer. However, the impact of the reproductive and non-reproductive risk...
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Spatiotemporal dynamics of the CD11c+ microglial population in the mouse brain and spinal cord from developmental to adult stages
CD11c-positive (CD11c + ) microglia have attracted considerable attention because of their potential implications in central nervous system (CNS)...
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Germline T cell receptor exchange results in physiological T cell development and function
T cell receptor (TCR) transgenic mice represent an invaluable tool to study antigen-specific immune responses. In the pre-existing models, a...
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Effects of cannabidiol in post-stroke mood disorders in neonatal rats
BackgroundNeonatal rats can manifest post-stroke mood disorders (PSMD) following middle cerebral artery occlusion (MCAO). We investigated whether...
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Repeated Sevoflurane Exposures in Neonatal Rats Increased the Brain Vulnerability to Future Stress Exposure and Resulted in Fear Extinction Deficit
Sevoflurane anesthesia during neonatal period was reported to sensitize the rodent animals to stress later in life. The authors tested the hypothesis...
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Soil degradations in the IGP of central Haryana, India–a spatial assessment for reclamation and management
Natural and anthropogenic processes are primary drivers for soil degradations in the Gangetic plain of India. Indian Remote Sensing (IRS) data was...
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Presence of a mouse mammary tumour virus-like in feline lymphomas: a preliminary study
The mouse mammary tumour virus (MMTV) is implicated in the aetiology of murine mammary carcinomas and a variant of it, the type B leukemogenic virus,...
