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miRNA Dysregulation in Schizophrenia
Schizophrenia is a complex neuropsychiatric disorder that alters synapse activity as well as neural circuits. An intricate intracellular network of...
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Oxford miRNA Gardener
Genetic traits are a curious question for biological research to elucidate the etiology of pathogenesis and are transmitted from cell to cell,...
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MiREx: mRNA levels prediction from gene sequence and miRNA target knowledge
Messenger RNA (mRNA) has an essential role in the protein production process. Predicting mRNA expression levels accurately is crucial for...
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Identification of miRNA-Target Gene-Transcription Factor Regulatory Network as Functional Motifs Involved in Glomerular Diabetic Nephropathy
AbstractThe gene regulatory approach based on retrieving information from the database provides a detailed characterization of the molecular...
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Programmed Evolution by miRNA Memory
Diseases are deeply implicated in the aberrant expression of microRNA (miRNA) genes. The RNA Wave 2000 dogma consists of four criteria, as first...
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MiRNA Immunity Against Virus and MiRNA Surveillance Against Tumor
Through the microRNA (miRNA) entangling target sorting/quantum miRNA language plus artificial intelligence (METS/MIRAI) analysis so far, it seems...
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MiRNA–Gene Activity Interaction Networks (miGAIN): Integrated Joint Models of miRNA–Gene Targeting and Disturbance in Signaling Pathways
Omics data are now inexpensive to collect in vast quantities, across a wide variety of not only multiple data platform, but also distinct functional...
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Identification and Validation of Lipid Metabolism Gene FASN-Associated miRNA in Wilms Tumor
miRNA has been a research hotspot in recent years and its scope of action is very wide, involving the regulation of cell proliferation,...
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The Concept of “Virus” Is the Same as Exosomal miRNA Gene
Virus is not the Latin word for “virus,” which means simply slimy liquid or poison. In the early twentieth century, viruses were referred to as...
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A preliminary study of the miRNA restitution effect on CNV-induced miRNA downregulation in CAKUT
BackgroundThe majority of CAKUT-associated CNVs overlap at least one miRNA gene, thus affecting the cellular levels of the corresponding miRNA. We...
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Machine Learning Using Gene-Sets to Infer miRNA Function
miRNA are regulators of cell phenotype, and there is clear evidence that these small posttranscriptional modifiers of gene expression are involved in...
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Machine learning-driven prediction of brain metastasis in lung adenocarcinoma using miRNA profile and target gene pathway analysis of an mRNA dataset
BackgroundBrain metastasis (BM) is common in lung adenocarcinoma (LUAD) and has a poor prognosis, necessitating predictive biomarkers. MicroRNAs...
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Experimental capture of miRNA targetomes: disease-specific 3′UTR library-based miRNA targetomics for Parkinson’s disease
The identification of targetomes remains a challenge given the pleiotropic effect of miRNAs, the limited effects of miRNAs on individual targets, and...
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Potential miRNA-gene interactions determining progression of various ATLL cancer subtypes after infection by HTLV-1 oncovirus
BackgroundAdult T-cell Leukemia/Lymphoma (ATLL) is a rapidly progressing type of T-cell non-Hodgkin lymphoma that is developed after the infection by...
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CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
BackgroundCalcific aortic valve disease (CAVD) is a common valve disease with an increasing incidence, but no effective drugs as of yet. With the...
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Flaxseed oil fraction reverses cardiac remodeling at a molecular level: improves cardiac function, decreases apoptosis, and suppresses miRNA-29b and miRNA 1 gene expression
Flaxseed is an ancient commercial oil that historically has been used as a functional food to lower cholesterol levels. However, despite its...
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Almond miRNA Expression and Horticultural Implications
From the past, till now various improved almond cultivars with desired traits have been introduced through breeding programs based on classical and...
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Differential gene expression and miRNA regulatory network in coronary slow flow
Coronary slow flow (CSF) is characterized by slow progression of coronary angiography without epicardial stenosis. The aim of this study was to...
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Identification of potentially functional circRNAs and prediction of the circRNA-miRNA-hub gene network in mice with primary blast lung injury
ObjectivesPrimary blast lung injury (PBLI) is the main cause of death in blast injury patients, and is often ignored due to the absence of a specific...
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Endogenous miRNA Sponges
MicroRNAs (miRNAs) are a class of noncoding RNAs of 17–22 nucleotides in length with a critical function in posttranscriptional gene regulation....