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Circadian rhythm, ipRGCs, and dopamine signalling in myopia
Myopia, a common ophthalmic disorder, places a high economic burden on individuals and society. Genetic and environmental factors influence myopia...
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A melanopsin ganglion cell subtype forms a dorsal retinal mosaic projecting to the supraoptic nucleus
Visual input to the hypothalamus from intrinsically photosensitive retinal ganglion cells (ipRGCs) influences several functions including circadian...
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Increase in choroidal thickness after blue light stimulation of the blind spot in young adults
BackgroundBlue light activates melanopsin, a photopigment that is expressed in intrinsically photosensitive retinal ganglion cells (ipRGCs). The...
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Blue-light background impairs visual exogenous attention shift
Previous research into the effects of blue light on visual-spatial attention has yielded mixed results due to a lack of properly controlling critical...
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Synaptic inputs to displaced intrinsically-photosensitive ganglion cells in macaque retina
Ganglion cells are the projection neurons of the retina. Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment...
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The cognitive impact of light: illuminating ipRGC circuit mechanisms
Ever-present in our environments, light entrains circadian rhythms over long timescales, influencing daily activity patterns, health and performance....
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Prefrontal cortex neurons encode ambient light intensity differentially across regions and layers
While light can affect emotional and cognitive processes of the medial prefrontal cortex (mPFC), no light-encoding was hitherto identified in this...
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An ethologically relevant paradigm to assess defensive response to looming visual contrast stimuli
In the animal kingdom, threat information is perceived mainly through vision. The subcortical visual pathway plays a critical role in the rapid...
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Intrinsically Photosensitive Retinal Ganglion Cells: Assessment of Their Influence on Pupillary Responses in Primates
Pupillary responses in primates are driven by melanopsin-containing, intrinsically photosensitive retinal ganglion cells (ipRGCs) that project to the... -
Patch-Clamp Electrophysiological Analysis of Murine Melanopsin Neurons
Intrinsically photosensitive retinal ganglion cells (ipRGCs) regulate diverse aspects of mammalian physiology, including the synchronization of... -
Brightness perception under photopic conditions: experiments and modeling with contributions of S-cone and ipRGC
In 1924, the CIE published and standardized the photopic luminous efficiency function. Based on the standardized curve, luminous flux in lumens,...
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Intrinsisch photosensitive retinale Ganglienzellen
BackgroundMelanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGC) area third class of photoreceptors in the retina in...
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The retinal ipRGC-preoptic circuit mediates the acute effect of light on sleep
Light regulates daily sleep rhythms by a neural circuit that connects intrinsically photosensitive retinal ganglion cells (ipRGCs) to the circadian...
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Smartphone-Based Pupillometer with Chromatic Stimuli to Screen Neuro-Ophthalmological Diseases
Pupillometry technique has gained an increased interest over the years as it allows to objectively assess patient’s consciousness and... -
In search of blue-light effects on cognitive control
People are constantly exposed to blue light while engaging in work. It is thus crucial to understand if vast exposure to blue light influences...
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Molecular determinants of response kinetics of mouse M1 intrinsically-photosensitive retinal ganglion cells
Intrinsically-photosensitive retinal ganglion cells (ipRGCs) are non-rod/non-cone retinal photoreceptors expressing the visual pigment, melanopsin,...
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Melanopic stimulation does not alter psychophysical threshold sensitivity for luminance flicker
In addition to the rod and cone photoreceptors the retina contains intrinsically photosensitive retinal ganglion cells (ipRGCs). These cells express...
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Identification of long noncoding RNAs in injury-resilient and injury-susceptible mouse retinal ganglion cells
BackgroundEmerging evidence indicates that long noncoding RNAs (lncRNAs) are important regulators of various biological processes, and their...
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Effects of Post-awakening Light Exposure on Heart Rate Variability in Healthy Male Individuals
Light-induced effects on the autonomic nervous system (ANS) are assumed to be mediated by retinal projections to the hypothalamic suprachiasmatic...