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Genetic Aspects of iNPH
Idiopathic Normal Pressure HydrocephalusNormal pressure hydrocephalus (iNPH) is a complex and multifactorial condition. Although the disease appears... -
Diffusion tensor imaging helps identify shunt-responsive normal pressure hydrocephalus patients among probable iNPH cohort
The aim of this study was to investigate whether white matter changes as measured by diffusion tensor imaging (DTI) can help differentiate...
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Lumboperitoneal Shunt for iNPH
Lumboperitoneal shuntLumboperitoneal shunt (LPS), a creative development based on the lumbar puncture technique used in the cerebrospinal... -
Resting-state functional-MRI in iNPH: can default mode and motor networks changes improve patient selection and outcome? Preliminary report
BackgroundIdiopathic normal pressure hydrocephalus (iNPH) is a progressive and partially reversible form of dementia, characterized by impaired...
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Open-aqueduct LOVA, LIAS, iNPH: a comparative clinical-radiological study exploring the “grey zone” between different forms of chronic adulthood hydrocephalus
PurposeThe definition of chronic adult hydrocephalus encompasses different pathological entities with overlap** characteristics, including...
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Ventricular volume in relation to lumbar CSF levels of amyloid-β 1–42, tau and phosphorylated tau in iNPH, is there a dilution effect?
BackgroundLevels of the biomarkers amyloid-β 1–42 (Aβ42), tau and phosphorylated tau (p-tau) are decreased in the cerebrospinal fluid (CSF) of...
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Incidental findings of typical iNPH imaging signs in asymptomatic subjects with subclinical cognitive decline
BackgroundThe etiology of idiopathic normal pressure hydrocephalus (iNPH) remains unclear. Little is known about the pre-symptomatic stage. This...
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Extended Lumbar Drainage: Supplementary Test to Diagnose Shunt Responsive iNPH
Predicting shunt responsivenessShunt responsiveness in patients with suspected normal pressure hydrocephalusNormal pressure hydrocephalus can be a... -
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Evaluating the cerebrospinal fluid tap test with the Hellström iNPH scale for patients with idiopathic normal pressure hydrocephalus
BackgroundThe cerebrospinal fluid tap test (CSF TT) is used for selecting shunt surgery candidates among patients with idiopathic normal pressure...
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Anterior callosal angle correlates with gait impairment and fall risk in iNPH patients
BackgroundIn idiopathic normal pressure hydrocephalus (iNPH), gait and balance impairment is the most frequent symptom, and it is often associated...
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iNPH with parkinsonism: response to lumbar CSF drainage and ventriculoperitoneal shunting
ObjectivesTo evaluate clinical response after external lumbar drainage (ELD) and ventriculoperitoneal shunting (VPS) in a cohort of patients with...
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The metabolic spatial covariance pattern of definite idiopathic normal pressure hydrocephalus: an FDG PET study with principal components analysis
Identification of patients with idiopathic normal pressure hydrocephalus (iNPH) in a collective with suspected neurodegenerative disease is...
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Ventriculoperitoneal shunt patients and glaucoma: a cohort analysis of the NPH registry
BackgroundIdiopathic Normal Pressure Hydrocephalus (iNPH) is a chronic condition affecting the elderly. It is characterized by a triad of symptoms...
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Clinical Symptoms and Examination
Idiopathic Normal Pressure HydrocephalusNormal pressure hydrocephalus (iNPH) is one of the treatable clinical entities and, therefore, it is very... -
The impact of telomere length on the risk of idiopathic normal pressure hydrocephalus: a bidirectional Mendelian randomization study
Idiopathic normal pressure hydrocephalus (iNPH) affects mainly aged populations. The gradual shortening of telomere length (TL) is one of the...
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Levels of inflammatory cytokines MCP-1, CCL4, and PD-L1 in CSF differentiate idiopathic normal pressure hydrocephalus from neurodegenerative diseases
BackgroundNeuroinflammatory processes have been suggested to play a role in the pathophysiology of neurodegenerative diseases and post-hemorrhagic...
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Choroidal morphology and microvascular structure in eyes of patients with idiopathic normal pressure hydrocephalus before and after ventriculo-peritoneal shunt surgery
The present study aims to investigate the choroidal morphology and microvascular structure in eyes of patients with idiopathic normal pressure...
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10-year mortality, causes of death and cardiovascular comorbidities in idiopathic normal pressure hydrocephalus
ObjectiveThe objective was to investigate 10-year mortality, causes of death and cardiovascular comorbidity in idiopathic normal pressure...
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Sarcopenia in older patients with idiopathic normal pressure hydrocephalus: an observational study from a single geriatric clinic in Turkey
ObjectiveIdiopathic normal pressure hydrocephalus (iNPH), a classical triad of gait abnormality, cognitive disturbance, and urinary incontinence,...