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Synergistic psychedelic - NMDAR modulator treatment for neuropsychiatric disorders
Modern research data suggest a therapeutic role for serotonergic psychedelics in depression and other neuropsychiatric disorders, although...
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Antibiotics That Inhibit Cell Wall Synthesis
Structure of the bacterial cell wall, the metabolic pathway for the biosynthesis of the cell wall, and various antibiotics affecting the different...
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Antibiotics That Inhibit Cell Wall Synthesis
Structure of the bacterial cell wall, the metabolic pathway for the biosynthesis of cell wall, and various antibiotics affecting various stages of...
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Nanosuspensions: a new approach for organ and cellular targeting in infectious diseases
Most of the infectious diseases depending upon the stage of infection need treatment at least for a month to several years e.g. tuberculosis,...
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Rational Approaches to Antibacterial Discovery: Pre-Genomic Directed and Phenotypic Screening
After the discovery of antibacterial chemicals and antibiotics through the 1950s by empirical assays based on growth inhibition, methods gradually...
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Cell Wall Targeted Antibiotics
The biosynthesis of murein occurs in three stages, which take place in (1) the cytoplasm forming muropeptide precursors, (2) the inner side of the...
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Aus Mikroorganismen hergestellte Arzneistoffe
Die Produktion von Arzneistoffen durch Mikroorganismen blickt auf eine lange Geschichte zurück: Man denke an die Gewinnung von Ethylalkohol aus...
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Manipulation of ruminal fermentation
Ruminant animals have two metabolic systems that differ in their nutrient requirements: microbial metabolism in the rumen and mammalian metabolism in...
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Antitubercular drugs
Isoniazid (isonicotinic acid hydrazine, INH) was first found to have in vitro activity against Mycobacterium sp. in 1945. In 1952, INH was reported...
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Experimental Evaluation of Efficacy
Experiments offer the possibility of varying several conditions and thus of assessing the importance of particular technical details. Studies of the...
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Chemical Manipulation of Rumen Metabolism.
Ruminant feed is exposed to fermentative digestion by the rumen microbial population before hydrolytic digestion by animal enzymes can occur. Total...
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The pathway ofD-cycloserine biosynthesis inStreptomyces garyphalus
Incubation experiments using washed cells and toluene treated cells of Streptomyces garyphalus showed that O-acetyl- L -serine and hydroxyurea are...
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Hydroxyurea, a natural metabolite and an intermediate in d-cycloserine biosynthesis in streptomyces garyphalus
It was found that hydroxyurea, l -arginine and l -citrulline respectively significantly stimulated the formation of d -cycloserine in Streptomyces...
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The presence of two serine racemases in Streptomyces garyphalus, a d-cycloserine producer
Two serine racemases (I and II) were isolated from Streptomyces garyphalus . Serine racemase I (molecular weight 93,000) was purified to a single band...
