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Topical and Transdermal Drug Delivery
This chapter reviews numerous concepts relevant to drug delivery topically and transdermally. Topics covered include the skin’s function barrier,... -
Transdermal Drug Delivery Systems
The transdermal drug delivery systems, also known as TDDS, are the most effective alternative to the oral and parenteral routes to deliver... -
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Non-invasive transdermal delivery of biomacromolecules with fluorocarbon-modified chitosan for melanoma immunotherapy and viral vaccines
Transdermal drug delivery has been regarded as an alternative to oral delivery and subcutaneous injection. However, needleless transdermal delivery...
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Nanoparticle-Loaded Microneedle Patch for Transdermal Delivery of Letrozole
Transdermal drug delivery methods offer significant advantages over oral or hypodermic alternatives. By avoiding the initial breakdown of medication...
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Iontophoresis-driven microneedle patch for the active transdermal delivery of vaccine macromolecules
COVID-19 has seriously threatened public health, and transdermal vaccination is an effective way to prevent pathogen infection. Microneedles (MNs)...
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A Percutaneous Delivery System for a Nicotinamide Transdermal Therapeutic System
Abstract —A percutaneous delivery system for nicotinamide is developed and its functional properties are studied in vitro. Four compositions of the...
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3D printing redefines microneedle fabrication for transdermal drug delivery
Microneedles (MNs) have emerged as an innovative, virtually painless technique for intradermal drug delivery. However, the complex and costly...
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Organic clay-based fast dissolving microneedles for efficient transdermal delivery of therapeutic proteins
PurposeMost protein drugs on the market are available in injectable dosage forms due to their metabolic instability and low membrane permeability,...
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Thyme Oil–Containing Fluconazole-Loaded Transferosomal Bigel for Transdermal Delivery
The objective of the present research was to develop fluconazole-loaded transferosomal bigels for transdermal delivery by employing statistical...
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Innovative freeze-drying technique in the fabrication of dissolving microneedle patch: Enhancing transdermal drug delivery efficiency
Microneedle patch (MNP) has become a hot research topic in the field of transdermal drug delivery due to its ability to overcome the stratum corneum...
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Design, optimization, and evaluation for a long-time-released transdermal microneedle delivery system containing estradiol
Transdermal drug delivery systems (TDDS) have drawbacks such as poor absorption, low blood concentration, and delayed effects. Dissolving microneedle...
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Dendrimer-conjugated isotretinoin for controlled transdermal drug delivery
BackgroundIn the present study, we aimed to develop a novel isotretinoin delivery model for treating skin diseases, revealing its potential...
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Revolutionizing Hypertension Management: Cutting-Edge Microneedle Patch Infused with Zinc Oxide Nanoparticles for Advanced Transdermal Drug Delivery
Transdermal drug delivery methods prove markedly superior to oral or hypodermic alternatives. By circumventing first-pass medication metabolism and...
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Ultrathin silk nanofiber–carbon nanotube skin tattoos for wirelessly triggered and temperature feedbacked transdermal drug delivery
Transdermal drug delivery has emerged as an alternative to conventional drug delivery systems as it enables painless and convenient drug...
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Deep eutectic solvent self-assembled reverse nanomicelles for transdermal delivery of sparingly soluble drugs
BackgroundTransdermal delivery of sparingly soluble drugs is challenging due to their low solubility and poor permeability. Deep eutectic solvent...
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Characterization of Transdermal Drug Delivery Systems: Retrospect and Future Prospects
The world of drug delivery has witnessed a profound transformation with the emergence and evolution of transdermal drug delivery systems (TDDS). TDDS... -
Acoustic metamaterials-driven transdermal drug delivery for rapid and on-demand management of acute disease
Transdermal drug delivery provides convenient and pain-free self-administration for personalized therapy. However, challenges remain in treating...
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Investigation of Paracetamol Entrapped Nanoporous Silica Nanoparticles in Transdermal Drug Delivery System
An effort was made to administer paracetamol drug through transdermal patch, as no such formulation of this drug has been developed yet. The primary...
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Tailored Transdermal Drug Delivery System for Pain Management: Development and Evaluation of Clonidine Hydrochloride/Sodium Montmorillonite Composite Patch
Researchers are always coming up with new techniques and methods to ensure that drug delivery systems are secure, therapeutically efficient, and...