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  1. Intravenous Thrombolysis

    Intravenous thrombolysis with alteplase is the standard of care in patients with eligible acute ischemic stroke patients within 4.5 h of symptom...
    Anas Alrohimi, Ashfaq Shuaib, ... Mahesh Pundlik Kate in Ischemic Stroke Therapeutics
    Chapter 2024
  2. Thrombolysis

    I had thrown my notice of termination in the mailbox of my nursing manager. After 13 years in the intensive care unit, many weekends and two children...
    Franziska Böhler in Case Studies in Emergency Medicine
    Chapter 2023
  3. Thrombolysis before venoarterial ECMO for high-risk pulmonary embolism: a retrospective cohort study

    Purpose

    Despite systemic thrombolysis, a few patients with high-risk pulmonary embolism (PE) remain hemodynamically unstable. Venoarterial...

    David Levy, Ouriel Saura, ... Matthieu Schmidt in Intensive Care Medicine
    Article 24 June 2024
  4. Tea polyphenol-derived nanomedicine for targeted photothermal thrombolysis and inflammation suppression

    Thrombotic diseases impose a significant global health burden, and conventional drug-based thrombolytic therapies are encumbered by the risk of...

    Hui Wang, Cui Tang, ... Wenhu Zhou in Journal of Nanobiotechnology
    Article Open access 03 April 2024
  5. Evaluating the effects of simulation training on stroke thrombolysis: a systematic review and meta-analysis

    Background

    Ischaemic strokes are medical emergencies, and reperfusion treatment, most commonly intravenous thrombolysis, is time-critical....

    Sameera Aljuwaiser, Abdel Rahman Abdel-Fattah, ... Alyaa Mostafa in Advances in Simulation
    Article Open access 29 February 2024
  6. Thrombolysis in Stroke-Heart Syndrome: a useful tool for neurocardiac wellness?

    Introduction

    Stroke-heart syndrome is a physiopathological condition of cardiac suffering due to cerebral injury secondary to major vessel occlusion...

    Ilario Scali, Marcello Naccarato, ... Paolo Manganotti in Journal of Neurology
    Article 11 January 2024
  7. Mortality outcomes and predictors of failed thrombolysis following STEMI thrombolysis in a non-PCI capable tertiary hospital: a 5-year analysis

    Pharmacological reperfusion remains the primary strategy for ST-elevation myocardial infarction (STEMI) in low- and medium-income countries....

    Hock Peng Koh, Adyani Md Redzuan, ... Noel Thomas Ross in Internal and Emergency Medicine
    Article 17 January 2023
  8. Dual-mode nanoprobe strategy integrating ultrasound and near-infrared light for targeted and synergistic arterial thrombolysis

    Efficient thrombolysis in time is crucial for prognostic improvement of patients with acute arterial thromboembolic disease, while limitations and...

    Zhiwen Wang, Nan Jiang, ... Bo Hu in Journal of Nanobiotechnology
    Article Open access 03 June 2024
  9. Efficacy and Safety of Alteplase Combined with Urinarykallid for Intravenous Thrombolysis on Acute Cerebral Infarction

    Abstract

    This study aimed to explore the efficacy and safety of alteplase combined with urinarykallid for the intravenous thrombolysis of patients...

    Jiahui Shao, Linyi Bao, ... Yun Chen in Neurochemical Journal
    Article 01 March 2024
  10. Predicting ineffective thrombolysis in acute ischemic stroke with clinical and biochemical markers

    **Ischemic stroke remains a leading cause of morbidity and mortality globally. Despite the advances in thrombolytic therapy, notably recombinant...

    Yinglei Li, Ning Li, ... Litao Li in Scientific Reports
    Article Open access 11 June 2024
  11. Acoustic Vortex-Assisted Thrombolysis Treatment in a Pulmonary Embolism Model Using a Miniature Ultrasound Catheter

    Purpose

    Pulmonary embolism (PE) occurs when a blood clot, usually from the deep veins of the legs, travels through the bloodstream and becomes lodged...

    Zong-Han Hsieh, Chun-Yen Lai, ... Chih-Kuang Yeh in Journal of Medical and Biological Engineering
    Article 15 June 2024
  12. Perspective/Commentary: The Transformation of STEMI Care with Thrombolysis in Paramedicine

    The integration of thrombolysis into paramedicine practice has brought about a significant paradigm shift in the treatment and prognosis of patients...

    Sonja Jane Maria in Intensive Care Research
    Article Open access 31 January 2024
  13. Repeated intravenous thrombolysis in recurrent ischemic stroke within 3 months: a systematic review

    Background

    Repeated intravenous thrombolysis (RIVT) within 3 months is an off-guideline therapy, however, may be an effective and safe way to treat...

    Si-Yuan Wen, Fei-Fei Chen, ... Chang-Qing Zhou in BMC Neurology
    Article Open access 27 November 2023
  14. Systemic thrombolysis with newer thrombolytics vs anticoagulation in acute intermediate risk pulmonary embolism: a systematic review and meta-analysis

    Background

    Randomized controlled trials (RCTs) comparing systemic thrombolysis to anticoagulation in intermediate risk pulmonary embolism (PE) have...

    Don Mathew, Susmitha Seelam, ... Utsav Shrestha in BMC Cardiovascular Disorders
    Article Open access 29 September 2023
  15. Superselective Arterial Hyaluronidase Thrombolysis is an Effective Treatment for Hyaluronic Acid-Induced Retinal Artery Occlusion: Study in a Rabbit Model

    Background

    There are serious complications associated with hyaluronic acid (HA) facial injections, including vision impairment due to retinal artery...

    **ao Xu, Xuer Sun, ... Minliang Chen in Aesthetic Plastic Surgery
    Article 01 March 2024
  16. Association of Atrial Fibrillation with Remote Intracerebral Hemorrhage After Intravenous Thrombolysis: Results from a Multicenter Study in China

    Introduction

    This study aimed to investigate the association between atrial fibrillation (AF), particularly newly diagnosed AF, and remote...

    **aoling Pan, Yingjian Pei, ... Zhicai Chen in Neurology and Therapy
    Article Open access 30 November 2023
  17. Predictive role of pre-thrombolytic hs-CRP on the safety and efficacy of intravenous thrombolysis in acute ischemic stroke

    Purpose

    To investigate the predictive role of pre-thrombolytic high sensitivity C-reactive protein (hs-CRP) on the safety and efficacy of intravenous...

    Xu-Dong Cheng, Duo-Zi Wang, ... Neng-Wei Yu in BMC Neurology
    Article Open access 23 June 2023
  18. An Explainable Machine-Learning Model to Analyze the Effects of a PCSK9 Inhibitor on Thrombolysis in STEMI Patients

    Purpose

    Thrombolysis, a timely and simple reperfusion therapy, does not have a sufficiently high success rate in patients with ST-segment elevation...

    Pengyu Zhao, Jia Zhou, ... Yonghong Hou in Journal of Medical and Biological Engineering
    Article 31 May 2023
  19. Stroke with large vessel occlusion in the posterior circulation: IV thrombolysis plus thrombectomy versus IV thrombolysis alone

    Efficacy and safety of mechanical thrombectomy (MT) for stroke with posterior circulation large vessel occlusion (LVO) is still under debate. We...

    Manuel Cappellari, Valentina Saia, ... Danilo Toni in Journal of Thrombosis and Thrombolysis
    Article 28 June 2023
  20. IV thrombolysis plus thrombectomy versus IV thrombolysis alone for minor stroke with anterior circulation large vessel occlusion from the IRETAS and Italian SITS-ISTR cohorts

    Introduction

    The aim of this study was to compare the outcomes of patients treated with intravenous thrombolysis (IVT) <4.5 h after symptom onset plus...

    Manuel Cappellari, Giovanni Pracucci, ... on behalf of the IRETAS group in Neurological Sciences
    Article 17 July 2023
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