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Synthesis, Characterization, and Antimicrobial Evaluation of Some Novel 3′-(6-(Substituted Phenyl)-4-Phenyl-6H-1,3-Thiazine-2-yl)Spiro[Indoline-3,3′-Isothiazolidine]-2,4′-Dione Derivatives
Thiazolidinediones (TZDs) are the vital component of a number of pharmaceuticals and biologically active compounds. Owing to the diversified...
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Effect of tricyclic 1,2-thiazine derivatives in neuroinflammation induced by preincubation with lipopolysaccharide or coculturing with microglia-like cells
BackgroundAlzheimer’s disease (AD) is considered the most common cause of dementia among the elderly. One of the modifiable causes of AD is...
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Theoretical Study of the Vibronic Structure of the Absorption and Fluorescence Spectra of Thiazine Dyes
Theoretical modeling of changes in the vibronic absorption and fluorescence spectra in the molecules of two dyes of the thiazine series – methylene...
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Recent methods for the synthesis of fused pyrazolo[3,4(4,3)-d]thiazoles and pyrazolo[3,4(4,3)-d][1,4]thiazines (microreview)
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Two Crystal Structures of Benzo-1,2-Thiazine-S,S-Dioxide with a Condensed Norbornane Fragment Differing in the Configuration of the Nitrogen Atom in the Molecule
AbstractConfiguration lability of the nitrogen atom in the –N(H)–SO 2 – group of the cyclic sulfonamide molecule determines the existence of two...
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Electrochemical and Theoretical Investigations of Ethyl 3-Phenyl-2H-Benzo[b][1,4]Thiazine-2-Carboxylate as an Inhibitor for Mild Steel Corrosion in 200 ppm of Sodium Chloride Medium
The effect of new heterocyclic compounds, namely ethyl 3-phenyl-2H-benzo[b][1,4]thiazine-2-carboxylate (E-PBTC) on mild steel (MS) corrosion in...
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CRYSTAL STRUCTURE OF SULFINAMIDES OF THE THIAZINE SERIES: FEATURES OF TRANSFERRING THE OPEN-CHAIN SUPRAMOLECULAR SYNTHON FROM THE RACEMIC TO HOMOCHIRAL ENVIRONMENT
AbstractThe crystal structures of four representatives of sulfinamides of the thiazine series are comparatively analyzed for the occurrence of...
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Microwave-Assisted Synthesis of Sulfur and Nitrogen-Containing Heterocycles
This chapter aims to review recent developments in the synthesis of sulfur and nitrogen-containing heteroaromatic compounds under conditions that...
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Reactions of substituted 1H-imidazole-2-thiols with pent-2-en-4-yn-1-ones
The base-catalyzed reaction between 4-phenyl-1 H -imidazole-2-thiol and 1,5-diaryl-substituted ( E )-pent-2-en-4-yn-1-ones proceeded with the involvement...
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FORMATION OF A SYMMETRIC SECONDARY PACKING MOTIF AS THE REASON OF THE CRYSTALLIZATION OF ENANTIOPURE MENTHANYL SULFONE WITH TWO INDEPENDENT MOLECULES
AbstractIt is established from XRD data that a new compound, enantiopure menthanyl sulfone, tends to crystallize with two independent molecules per...
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Crystal Structure of Tetrachloroferrate(III) Complex with Methylene Blue
The crystal structure of tetrachloroferrate(III) complex with methylene blue, [Mb] + [FeCl 4 ] − (where [Mb] + methylthioninium or...
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Synthesis of New Derivatives of 5-Acetyl-4-hydroxy-2H-1,3-thiazine-2,6(3H)-dione
5-Acetyl-4-hydroxy-2 H -1,3-thiazine-2,6(3 H )-dione reacted with cyclohexyl and benzyl (4-aminophenyl)carbamates in boiling ethanol in the presence of a...
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Prediction of cytochrome P450-mediated bioactivation using machine learning models and in vitro validation
Cytochrome P450 (P450)-mediated bioactivation, which can lead to the hepatotoxicity through the formation of reactive metabolites (RMs), has been...
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Synthesis, Molecular Docking, and Hemorheological Activity of New 4-(Thien-2-yl)-3-aminopyridine-2(1H)-one Derivatives
AbstractOn the basis of 4-(thien-2-yl)-3-aminopyridine-2(1 H )-one, the corresponding chloroacetamide and condensed 1 H -pyrido[2,3 -b ][1,4]oxazine-2(3H)-...
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Dynamic stereochemistry at work: Configurational lability of nitrogen and sulfur atoms within a sulfonamide moiety as a cause of forming supramolecular diastereomers in crystals
Here, we present the crystal structure peculiarities of four benzo-1,2-thiazine-S,S-dioxides with a condensed norbornane fragment. The structure of...
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New Methods of Synthesis of Fused Maleimides
AbstractThe review covers publications over the past decade on new methods of synthesis of pyrrolo[3,4- b ]pyrrole-4,6(1 H ,5 H )-diones, 4 H -thieno[2,3- c ]pyrrole-4,6(5...
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A methylene blue assay for the quantification of fucoidan – A specific application for seaweed extracts
Fucoidan is a fucose-rich sulfated polysaccharide found mainly in brown seaweeds. Fucoidan has recently gained much attention due to its bioactive...
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Reactivity of Olefin Functionalities of Dicyclopentadiene in the Diels–Alder Reaction with Thionylaniline
AbstractThe reaction of thionylaniline with dicyclopentadiene has afforded the Diels–Alder adduct which has been oxidized into the corresponding...
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Methods for the synthesis of imidazo[2,1-b][1,3]thiazines, their annulated and hydrogenated analogs
The review systematizes literature data on methods for constructing imidazo[2,1- b ]thiazines and their hydrogenated analogs. The synthetic approaches...
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Carbodithioic Acid Esters
Recent works (published over the last decade) on the syntheses and reactions of dithioic acid esters (dithioates) are reviewed. Dithioates have been...