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Health-related quality of life in Chinese SLE patients: evidence from 1568 SLE patients and 2610 healthy controls
ObjectiveTo investigate the effects of systemic lupus erythematosus (SLE) on health-related quality of life (HRQOL), the relationship between disease...
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Systemischer Lupus erythematodes (SLE) bei Kinder und Jugendlichen
Der SLE ist im Kindes- und Jugendalter eine schwerwiegende Diagnose. Fast ein Fünftel aller SLE-Patienten erkranken als Kinder oder Jugendliche,... -
Identifying Severity Clusters in SLE Patients
Machine learning (ML) has a successful impact in healthcare data mining. We use unsupervised ML methods to extract features and identify subgroups of... -
Subclinical pleuro-pulmonary disease in patients with SLE: functional and radiological methods
BackgroundSystemic lupus erythematosus (SLE) is a multisystem autoimmune disease with highest prevalence of chest involvement; however, early...
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Possible Role of Dysbiosis of the Gut Microbiome in SLE
Purpose of ReviewThe resident gut microbiota serves as a double-edged sword that aids the host in multiple ways to preserve a healthy equilibrium and...
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Worse cardiovascular and renal outcome in male SLE patients
Systemic lupus erythematosus (SLE) in males is rare and poorly understood. Thus, still little is known about sex differences in SLE. We set out to...
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Evaluation of Type 2 SLE symptoms in patients with a range of lupus nephritis activity
BackgroundType 2 systemic lupus erythematosus (SLE) symptoms, including fatigue, fibromyalgia, and brain fog, contribute to poor health-related...
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Targeting DORIS Remission and LLDAS in SLE: A Review
Remission is the established therapeutic goal for patients with systemic lupus erythematosus (SLE) and is currently defined by the widely adopted...
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Genetics of SLE: mechanistic insights from monogenic disease and disease-associated variants
The past few years have provided important insights into the genetic architecture of systemic autoimmunity through aggregation of findings from...
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Interaction of 5-HTTLPR and SLE disease status on resting-state brain function
BackgroundNeuropsychiatric involvement in systemic lupus erythematosus (SLE) is a common clinical manifestation. In SLE patients, cerebral function...
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Platelet ındices as potential biomarkers of perinatal outcomes in women with SLE during pregnancy
AimThis study aimed to assess the platelet parameters and their prognostic value for perinatal outcomes in pregnant women with systemic lupus...
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Negative ANA-IIF in SLE patients: what is beyond?
AbstractThe antinuclear antibody (ANA) test has high sensitivity in diagnosing and classifying systemic lupus erythematosus (SLE).
Objectives ... -
Deep learning-enabled automatic screening of SLE diseases and LR using OCT images
Optical coherence tomography (OCT) is a noninvasive imaging technique that enables the visualization of tissue microstructure in vivo. Recent studies...
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Identification of EPSTI1 as a new potential biomarker for SLE based on GEO database
ObjectiveSystemic lupus erythematosus (SLE) is a chronic autoimmune disease with highly heterogeneous. The aim of this study is to find the key genes...
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Sle-CNN: a novel convolutional neural network for sleep stage classification
Many classical methods have been used in automatic sleep stage classification but few methods explore deep learning. Meanwhile, most deep learning...
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High throughput sequencing revealed enhanced cell cycle signaling in SLE patients
The multi-system involvement and high heterogeneity of systemic lupus erythematosus (SLE) pose great challenges to its diagnosis and treatment. The...
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Genetic polymorphisms in genes involved in the type I interferon system (STAT4 and IRF5): association with Asian SLE patients
Systemic lupus erythematosus (SLE) is a common autoimmune disease with a polymorphic clinical presentation involving multisystem damages with...
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Pattern of disease expression in SLE patients with antiphospholipid antibodies: data from Indian Systemic Lupus Erythematosus Inception cohort (INSPIRE)
Antiphospholipid antibodies (APLA) are present in one-third of systemic lupus erythematosus (SLE) patients, and they are associated with both...
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Presentation of SLE after COVID vaccination in a pediatric patient
BackgroundThe outbreak of severe acute respiratory syndrome coronavirus 2 has had an enormous impact on global health. Vaccination remains one of the...