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1. N6-methyladenosine methylation in kidney injury

   Multiple mechanisms are involved in kidney damage, among which the role of epigenetic modifications in the occurrence and development of kidney...

   Qimeng Wang, **aoting Fan, ... Rong Wang in Clinical Epigenetics

   Article Open access 21 October 2023
   

2. RNA N6-methyladenosine (m6A) modification in HNSCC: molecular mechanism and therapeutic potential

   Head and neck squamous cell carcinoma ranks seventh in incidence of malignant tumours in the world. Although there are treatments including surgery,...

   **nyu Sun, Shengqiao Fu, ... Hanqiang Lu in Cancer Gene Therapy

   Article 23 May 2023
   

3. Manipulating the tumour immune microenvironment by N6-methyladenosine RNA modification

   N6-methyladenosine (m6A), a posttranscriptional regulatory mechanism, is the most common epigenetic modification in mammalian mRNA. M6A modifications...

   **nyu Sun, Huirong Wang, ... Hanqiang Lu in Cancer Gene Therapy

   Article 04 June 2024
   

4. N6-Methyladenosine Methylation of mRNA in Cell Apoptosis

   Apoptosis, a highly controlled homeostatic mechanism that eliminates single cells without destroying tissue function, occurs during growing...

   Lin Zhang, Jian **a in Molecular Neurobiology

   Article 02 December 2023
   

5. N6‐methyladenosine (m6A) Modification in Preeclampsia

   Recently, epitranscriptional modification of N6-methyladenosine (m6A) has received growing attention in the research on the pathogenesis of...

   Tingting Zhang, Ziyan Jiang, ... Lizhou Sun in Reproductive Sciences

   Article 07 June 2023
   

6. Role of N6-methyladenosine RNA modification in gastric cancer

   N6-methyladenosine (m6A) RNA methylation is the most prevalent internal modification of mammalian messenger RNA. The m6A modification affects...

   Si-Qi Ding, Xue-** Zhang, ... Dong-Qiu Dai in Cell Death Discovery

   Article Open access 13 July 2023
   

7. Method for the Enrichment of N6-Methyladenosine-Modified Cellular and HIV-1 RNA

   N6-methyladenosine (m6A) modification of RNA is an important area in studying viral replication, cellular responses, and host immunity. HIV-1 RNA...

   Tarun Mishra, Stacia Phillips, Li Wu in HIV Protocols

   Protocol 2024
   

8. The implications of N6-methyladenosine (m6A) modification in esophageal carcinoma

   Esophageal carcinoma (EC) is always diagnosed at advanced stage and its the mortality rate remains high. The patients usually miss the best...

   Cheng He, **ao Teng, ... Jian Hu in Molecular Biology Reports

   Article Open access 20 August 2023
   

9. Characterization of sexual maturity-associated N6-methyladenosine in boar testes

   Background

   The health and size of the testes are crucial for boar fertility. Testicular development is tightly regulated by epigenetics....

   Pengfei Zhang, Fei Zhang, ... Yunhai Zhang in BMC Genomics

   Article Open access 07 May 2024
   

10. The emerging roles of N6-methyladenosine RNA modifications in thyroid cancer

    Thyroid cancer (TC) is the most predominant malignancy of the endocrine system, with steadily growing occurrence and morbidity worldwide. Although...

    **aoxin Xu, Jiayao Zhao, ... Jiakang Jiang in European Journal of Medical Research

    Article Open access 01 November 2023
    

11. RNA N6-Methyladenosine Pathway Writer Genes Expression Levels and Clinical Severity of Infection in Covid-19 Patients

    Abstract

    Epigenetic modifications are known to be effective in the severity and mortality rate of SARS-CoV-2 infection. N6-methyladenosin (m6A) is a...

    Badel Arslan, Sevgi Baltacı, ... Serdal Arslan in Molecular Genetics, Microbiology and Virology

    Article 01 June 2023
    

12. New horizons for the role of RNA N6-methyladenosine modification in hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) is one of the most common malignancy, presenting a formidable challenge to the medical community owing to its...

    Yu-jia Li, Yang-ling Qiu, ... Shi-zhong Zheng in Acta Pharmacologica Sinica

    Article 09 January 2024
    

13. RNA N6-methyladenosine modification-based biomarkers for absorbed ionizing radiation dose estimation

    Radiation triage and biological dosimetry are critical for the medical management of massive potentially exposed individuals following radiological...

    Hongxia Chen, ** Zhao, ... Gangqiao Zhou in Nature Communications

    Article Open access 30 October 2023
    

14. N6-methyladenosine RNA modifications: a potential therapeutic target for AML

    N6-methyladenosine (m6A) RNA modification has recently emerged as an essential regulator of normal and malignant hematopoiesis. As a reversible...

    Rong Hu, Peiyun Liao, ... Yuhua Li in Annals of Hematology

    Article 07 August 2023
    

15. The role of N6-methyladenosine methylation in PAHs-induced cancers

    Polycyclic aromatic hydrocarbons (PAHs), which are a wide range of environmental toxicants, may act on humans through inhalation, ingestion, and skin...

    Yujie Wei, **aona Guo, ... **aoran Duan in Environmental Science and Pollution Research

    Article 04 November 2023
    

16. N6-methyladenosine modification governs liver glycogenesis by stabilizing the glycogen synthase 2 mRNA

    Hepatic glycogen is the main source of blood glucose and controls the intervals between meals in mammals. Hepatic glycogen storage in mammalian pups...

    **ang Zhang, Huilong Yin, ... Rui Zhang in Nature Communications

    Article Open access 17 November 2022
    

17. The interplay between N6-methyladenosine and precancerous liver disease: molecular functions and mechanisms

    N6-methyladenosine(m ⁶ A) is one of the most abundant modifications of mammalian cellular RNAs. m ⁶ A regulates various biological functions in...

    Zhihua Lv, Ruoxi Ran, ... **gtao Huang in Discover Oncology

    Article Open access 25 May 2023
    

18. N6-methyladenosine hypomethylation of circGPATCH2L regulates DNA damage and apoptosis through TRIM28 in intervertebral disc degeneration

    Circular RNAs (circRNAs) are a class of noncoding RNAs that have been found to be involved in intervertebral disc degeneration (IVDD) progression,...

    Zhenhao Chen, Jian Song, ... Hongli Wang in Cell Death & Differentiation

    Article 12 July 2023
    

19. RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation

    Neuroblastoma (NB) is a kind of typical life-threatening extracranial tumor in children. N6-methyladenosine (m6A) modification is closely related to...

    Kai Zhu, Tingting Gao, ... Zhibao Lv in Cell Death Discovery

    Article Open access 08 May 2023
    

20. METTL14-mediated N6-methyladenosine modification induces the ferroptosis of hypoxia/reoxygenation-induced cardiomyocytes

    Background

    Hypoxia/reoxygenation (H/R) induces cardiomyocyte ferroptosis, a core remodeling event in myocardial ischemia/reperfusion injury....

    Chunyu Zhao, Jianing Li in Journal of Cardiothoracic Surgery

    Article Open access 25 April 2024