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Levetiracetam (LEV)
Das Kapitel zeigt tabellarisch das Kurzprofil des Medikaments Levetiracetam (LEV).
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Levetiracetam
The pharmacokinetic characteristics of levetiracetam are described, and the interaction effects of concomitant antiseizure medications on...
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Levetiracetam
The effect of antacids, digoxin, esomeprazole, ketogenic diet, meropenem, oral contraceptives, pantoprazole; probenecid and warfarin on the...
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Real-World Evidence on Levetiracetam-Induced Hypokalemia: An Active Comparator Cohort Study
BackgroundLevetiracetam is an anti-seizure medication (ASM) with an established safety profile. However, a potential safety signal of hypokalemia...
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Levetiracetam Interaction with Direct Oral Anticoagulants: A Pharmacovigilance Study
BackgroundLevetiracetam is widely used in post-stroke epilepsy. However, it is suspected to possess P-glycoprotein (P-gp) induction properties, and...
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Levetiracetam versus Phenobarbitone for Management of Neonatal Seizures: A Systematic Review and Meta-analysis
ObjectivesTo review whether levetiracetam is non-inferior to phenobarbitone as the first-choice antiseizure medication (ASM).
MethodsThe authors...
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Immediate hypersensitivity reaction to levetiracetam: a case report study
BackgroundAnticonvulsant drugs are one of the most common causes of delayed hypersensitivity reactions, such as drug reaction with eosinophilia and...
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The efficacy of direct oral anticoagulants in patients on concomitant treatment with levetiracetam
Guidelines do not support the combination of direct oral anticoagulants (DOACs) and the antiepileptic drug levetiracetam, due to potential relevant...
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A case of glossopharyngeal neuralgia successfully treated with levetiracetam
BackgroundGlossopharyngeal neuralgia is a condition that causes severe pain in the throat during swallowing. Although carbamazepine is a viable...
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Efficacy and Safety of Levetiracetam on the Treatment of Spasticity in Neurologic Disorders: a Systematic Review
Spasticity is one of the disabling complications of various neurologic disorders. Its relief through available pharmacotherapy is oftentimes...
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Anti-convulsant Agents: Levetiracetam and Brivaracetam
Levetiracetam (LEV) and brivaracetam (BRV) are pyrrolidone derivate compounds binding at the presynaptic SV2A receptor site and thus representing...
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Effect of Levetiracetam on Cognition: A Systematic Review and Meta-analysis of Double-Blind Randomized Placebo-Controlled Trials
BackgroundStudies have suggested that levetiracetam may help improve cognitive function in patients with epilepsy. Recently, its efficacy in...
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Study of anticancer effects of platinum levetiracetam and levetiracetam via cancer biomarkers genes expression on HepG2 cell line
BackgroundHigh expression of some anticancer biomarkers such as telomerase and B cell lymphoma-2 ( Bcl-2), microRNA-21(miRNA-21), and low expression...
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Enhanced renal clearance impacts levetiracetam concentrations in patients with traumatic brain injury with and without augmented renal clearance
BackgroundThe purpose of this study was to examine the impact of ARC on levetiracetam concentrations during the first week following acute TBI. The...
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Effects of sodium valproate and levetiracetam on posterior segment parameters in children with epilepsy
PurposeTo evaluate changes in posterior segment parameters in pediatric patients with epilepsy using sodium valproate or levetiracetam monotherapy...
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Therapeutic Effect of Levetiracetam Against Thioacetamide-Induced Hepatic Encephalopathy Through Inhibition of Oxidative Stress and Downregulation of NF-κB, NLRP3, iNOS/NO, Pro-Inflammatory Cytokines and Apoptosis
Hepatic encephalopathy (HE) is a serious brain disorder which associated with neurological and psychiatric manifestations. Oxidative stress and...
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Evaluation of Levetiracetam Dosing Strategies for Seizure Prophylaxis Following Traumatic Brain Injury
BackgroundAlthough levetiracetam has been increasingly used as an alternative to phenytoin for early posttraumatic seizure prophylaxis following...
