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Definitive Radiotherapy in Locally Advanced Head and Neck Squamous Cell Cancer with Clinical Extranodal Extension
PurposeThe extranodal extension (ENE) in head and neck squamous cell carcinoma (HNSCC) is a potential poor prognostic factor. Clinical ENE (cENE) was...
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COX inhibitor use during definitive radiotherapy is associated with worse hearing preservation in patients with vestibular schwannoma
PurposePatients with vestibular schwannoma undergoing definitive radiotherapy commonly experience hearing loss due to tumor and treatment effects;...
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The role of the soft palate dose regarding normal tissue toxicities in older adults with head and neck cancer undergoing definitive radiotherapy
PurposeThe number of older adults with head and neck squamous cell carcinoma (HNSCC) is continuously increasing. Older HNSCC patients may be more...
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Upfront surgery versus definitive radiotherapy: competing risk analyses for cancer-specific and noncancer mortality in oropharyngeal cancer
PurposeThe optimal treatment strategy for oropharyngeal cancer (OPC) is undetermined. We aim to compare the survival outcomes of OPC patients treated...
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Outcomes of definitive carbon-ion radiotherapy for cT1bN0M0 esophageal squamous cell carcinoma
BackgroundA recent phase I/II study determined the optimal dose of definitive carbon-ion radiotherapy (CIRT) for cT1bN0M0 esophageal cancer. This...
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The clinical practice and dosimetric outcome of the manual adaptive planning during definitive radiotherapy for cervical cancer
ProposeTo evaluate the advantage of the manual adaptive plans comparing to the scheduled plans, and explored clinical factors predicting patients...
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Clinical course of longer than five years after definitive radiotherapy for nasopharyngeal carcinoma
BackgroundThis study aimed to reveal the long-term outcomes and late toxicities (> 5 years) after definitive intensity-modulated radiation therapy...
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Nomograms based on the lymphocyte–albumin–neutrophil ratio (LANR) for predicting the prognosis of nasopharyngeal carcinoma patients after definitive radiotherapy
Much evidence has accumulated to show that inflammation and nutritional status are associated with the prognosis of patients with various cancers....
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Treatment intensification strategies for men undergoing definitive radiotherapy for high-risk prostate cancer
PurposeTreatment intensification of external beam radiotherapy (EBRT) plays a crucial role in the treatment of high-risk prostate cancer.
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Dose-response relationship between volume base dose and tumor local control in definitive radiotherapy for vaginal cancer
ObjectiveThis study aimed to establish the dose-response relationship between volume base dose and tumor local control for vaginal cancer, including...
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Definitive Chemoradiotherapy
Radiotherapy has been used as a substitute for surgery or to alleviate symptoms in patients who are unfit to undergo surgical treatment. However, the...
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Prognostic value of baseline 18F-FDG PET/CT in patients with esophageal squamous cell carcinoma treated with definitive (chemo)radiotherapy
PurposeTo investigate the prognostic value of baseline 18 F-FDG PET/CT in patients with esophageal squamous cell carcinoma (ESCC) treated with...
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Role of primary tumor volume and metastatic lymph node volume in response to curative effect of definitive radiotherapy for locally advanced head and neck cancer
BackgroundStudies have shown mixed results concerning the role of primary tumor volume (TV) and metastatic lymph node (NV) volume in response to the...
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Prognostic significance of platelet-to-albumin ratio in patients with esophageal squamous cell carcinoma receiving definitive radiotherapy
Accumulating evidence indicates that inflammation and nutrition status are associated with clinical outcomes in patients with various malignancies....
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Radiotherapy for Meningioma
Meningiomas are the most common primary intracranial brain tumor, and have a heterogeneous biology and an unmet need for targeted treatment options....
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Advances and residual knowledge gaps in the neck management of head and neck squamous cell carcinoma patients with advanced nodal disease undergoing definitive (chemo)radiotherapy for their primary
PurposeSubstantial changes have been made in the neck management of patients with head and neck squamous cell carcinomas (HNSCC) in the past century....
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Prognostic value of PSA bounce after definitive radiotherapy revisited
BackgroundProstate-specific antigen (PSA) bounce after definitive radiotherapy has been reported as a predictor of improved biochemical...
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Whether individualized dose escalation should be recommended for lymph nodes with different sizes in the definitive radiotherapy of cervical cancer?
Background and purposeDose escalation for positive node maybe improve the regional control of patients with node-positive cervical cancer, but the...
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Prognostic value of tumor-infiltrating immune cells and immune checkpoints in elderly head-and-neck squamous cell carcinoma patients undergoing definitive (chemo)radiotherapy
Background and purposeTumor-infiltrating lymphocytes (TILs) are associated with locoregional control (LRC) in head-and-neck squamous cell carcinoma...
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PET-CT detection of local residual laryngeal carcinoma after definitive (chemo)radiotherapy
BackgroundPositron emission tomography and computed tomography (PET-CT) is currently recommended in evaluating the treatment response after...
