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Silica nanoparticles induce ovarian granulosa cell apoptosis via activation of the PERK-ATF4-CHOP-ERO1α pathway-mediated IP3R1-dependent calcium mobilization
Ambient particulate matters (PMs) have adverse effects in human and animal female reproductive health. Silica nanoparticles (SNPs), as a major...
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Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs
Platelets play a crucial role in cancer and thrombosis. However, the receptor-ligand repertoire mediating prostate cancer (PCa) cell-platelet...
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Antihyperalgesic effect of joint mobilization requires Cav3.2 calcium channels
The present study was undertaken to explore the relative contributions of Cav3.2 T-type channels to mediating the antihyperalgesic activity of joint...
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Fluorescence-coupled micropipette aspiration assay to examine calcium mobilization caused by red blood cell mechanosensing
Mechanical stimuli such as tension, compression, and shear stress play critical roles in the physiological functions of red blood cells (RBCs) and...
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Cytosolic Calcium Distribution and Thrombin Receptor Activation
Since, receptor plays significant role in calcium signalling and to understand the mechanism of signalling in detail; an essential component is the... -
FLIPR Calcium Mobilization Assays in GPCR Drug Discovery
Intracellular calcium mobilization can be measured using several methods varying in indicator dyes and devices used. In this chapter, we describe the... -
Very early migration of a calcar-guided short stem: a randomized study of early mobilization and the influence of a calcium phosphate coating with 60 patients
This study analyzed the migration of a calcar-guided short stem to determine the course of very early migration, as well as evaluated the effect of...
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Association between thymic hyperplasia and serum calcium level in Graves’ disease
BackgroundGraves' disease increases bone resorption in hyperthyroidism, leading to elevated serum calcium levels and a negative bone balance. Thymic...
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Early Mobilization in Neurocritical Care
Purpose of ReviewBed rest was a treatment recommended for critically ill patients admitted to the intensive care unit (ICU) that aimed to minimize...
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PKC-β modulates Ca2+ mobilization through Stim1 phosphorylation
BackgroundCalcium ions play a pivotal role in cell proliferation, differentiation, and migration. Under basal conditions, the calcium level is...
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Efficacy of prophylactic antibiotics for the prevention of neutropenic fever in patients with multiple myeloma receiving high-dose cyclophosphamide for stem cell mobilization
High-dose cyclophosphamide (HD-Cy) (3 g/m 2 ) plus granulocyte colony-stimulating factor (G-CSF) is a very effective regimen for peripheral blood stem...
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Metal mobilization from thawing permafrost to aquatic ecosystems is driving rusting of Arctic streams
Climate change in the Arctic is altering watershed hydrologic processes and biogeochemistry. Here, we present an emergent threat to Arctic watersheds...
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Disorders of Calcium: Hypercalcemia
This chapter provides causes, evaluation, clinical manifestations, biochemical abnormalities, and treatment of acute and chronic hypercalcemia... -
QSAR Studies on Calcium Channel Blockers
Calcium channel blockers (CCBs) have potential therapeutic uses against several cardiovascular and non-cardiovascular diseases. For vasospastic... -
Role of NAADP in Coordinating Spatiotemporal Aspects of Calcium Signalling
We outline the roles of two low molecular weight phosphorylated compounds as intracellular messengers in calcium signaling. These new intracellular... -
Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry
BackgroundCalcium (Ca 2+ ) signaling regulates various vital cellular functions, including integrin activation and cell migration. Store-operated...
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Identification of microbiogeochemical factors responsible for arsenic release and mobilization, and isolation of heavy metal hyper-tolerant bacterium from irrigation well water: a case study in Rural Bengal
In Bengal Delta Plain (West Bengal and Bangladesh), shallow aquifer (< 50 m) groundwater is often used in irrigation for paddy cultivation. The...
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Reserve mobilization and the role of primary metabolites during the germination and initial seedling growth of rubber tree genotypes
During seed germination until photoautotrophic establishment, the mobilization of seed-stored reserves represents the main source of carbon...
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Mobilization and Collection of HSCs in Children
Pediatric hematopoietic stem cell (HSC) products are crucial components of hematopoietic cell transplantation (HCT) in children. This chapter... -
Disorders of Calcium: Physiology
Calcium (Ca2+) is the most abundant divalent ion in the body. Approximately 1.2–1.3 kg of Ca2+ is present in a 70-kg individual. Of this amount, 99 %...