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  1. Silica nanoparticles induce ovarian granulosa cell apoptosis via activation of the PERK-ATF4-CHOP-ERO1α pathway-mediated IP3R1-dependent calcium mobilization

    Ambient particulate matters (PMs) have adverse effects in human and animal female reproductive health. Silica nanoparticles (SNPs), as a major...

    Fenglei Chen, Jiarong Sun, ... **long Zhang in Cell Biology and Toxicology
    Article 08 November 2022
  2. Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs

    Platelets play a crucial role in cancer and thrombosis. However, the receptor-ligand repertoire mediating prostate cancer (PCa) cell-platelet...

    Kaitlin Garofano, Kameron Rashid, ... Norman H. Lee in Scientific Reports
    Article Open access 17 February 2023
  3. Antihyperalgesic effect of joint mobilization requires Cav3.2 calcium channels

    The present study was undertaken to explore the relative contributions of Cav3.2 T-type channels to mediating the antihyperalgesic activity of joint...

    Daniel F. Martins, Victor Sorrentino, ... Gerald W. Zamponi in Molecular Brain
    Article Open access 18 July 2023
  4. Fluorescence-coupled micropipette aspiration assay to examine calcium mobilization caused by red blood cell mechanosensing

    Mechanical stimuli such as tension, compression, and shear stress play critical roles in the physiological functions of red blood cells (RBCs) and...

    Haoqing Wang, Peyman Obeidy, ... Lining Arnold Ju in European Biophysics Journal
    Article Open access 14 March 2022
  5. Cytosolic Calcium Distribution and Thrombin Receptor Activation

    Since, receptor plays significant role in calcium signalling and to understand the mechanism of signalling in detail; an essential component is the...
    Ritu Agarwal, Sunil Dutt Purohit, Kritika in Modeling Calcium Signaling
    Chapter 2024
  6. FLIPR Calcium Mobilization Assays in GPCR Drug Discovery

    Intracellular calcium mobilization can be measured using several methods varying in indicator dyes and devices used. In this chapter, we describe the...
    Grzegorz Woszczek, Elisabeth Fuerst, Thomas J. A. Maguire in G Protein-Coupled Receptor Screening Assays
    Protocol 2021
  7. Very early migration of a calcar-guided short stem: a randomized study of early mobilization and the influence of a calcium phosphate coating with 60 patients

    This study analyzed the migration of a calcar-guided short stem to determine the course of very early migration, as well as evaluated the effect of...

    Stefan Budde, Alexander Derksen, ... Michael Schwarze in Scientific Reports
    Article Open access 15 February 2024
  8. Association between thymic hyperplasia and serum calcium level in Graves’ disease

    Background

    Graves' disease increases bone resorption in hyperthyroidism, leading to elevated serum calcium levels and a negative bone balance. Thymic...

    **g Zeng, Lan Li, Dong Wei in BMC Endocrine Disorders
    Article Open access 29 January 2024
  9. Early Mobilization in Neurocritical Care

    Purpose of Review

    Bed rest was a treatment recommended for critically ill patients admitted to the intensive care unit (ICU) that aimed to minimize...

    Kristen Nobles, Kiersten Norby, ... Monisha A. Kumar in Current Treatment Options in Neurology
    Article 06 February 2024
  10. PKC-β modulates Ca2+ mobilization through Stim1 phosphorylation

    Background

    Calcium ions play a pivotal role in cell proliferation, differentiation, and migration. Under basal conditions, the calcium level is...

    Hye-** Song, In-Sook Jeon, ... Joong-Kook Choi in Genes & Genomics
    Article Open access 07 March 2022
  11. Efficacy of prophylactic antibiotics for the prevention of neutropenic fever in patients with multiple myeloma receiving high-dose cyclophosphamide for stem cell mobilization

    High-dose cyclophosphamide (HD-Cy) (3 g/m 2 ) plus granulocyte colony-stimulating factor (G-CSF) is a very effective regimen for peripheral blood stem...

    Li-qiong Hou, Jun-Ru Liu, ... Juan Li in Annals of Hematology
    Article Open access 25 January 2024
  12. Metal mobilization from thawing permafrost to aquatic ecosystems is driving rusting of Arctic streams

    Climate change in the Arctic is altering watershed hydrologic processes and biogeochemistry. Here, we present an emergent threat to Arctic watersheds...

    Jonathan A. O’Donnell, Michael P. Carey, ... Brett A. Poulin in Communications Earth & Environment
    Article Open access 20 May 2024
  13. Disorders of Calcium: Hypercalcemia

    This chapter provides causes, evaluation, clinical manifestations, biochemical abnormalities, and treatment of acute and chronic hypercalcemia...
    Chapter 2023
  14. QSAR Studies on Calcium Channel Blockers

    Calcium channel blockers (CCBs) have potential therapeutic uses against several cardiovascular and non-cardiovascular diseases. For vasospastic...
    Chapter
  15. Role of NAADP in Coordinating Spatiotemporal Aspects of Calcium Signalling

    We outline the roles of two low molecular weight phosphorylated compounds as intracellular messengers in calcium signaling. These new intracellular...
    Grant C. Churchill, Antony Galione in Understanding Calcium Dynamics
    Chapter
  16. Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry

    Background

    Calcium (Ca 2+ ) signaling regulates various vital cellular functions, including integrin activation and cell migration. Store-operated...

    Vikas Bhuria, Tobias Franz, ... Thomas Fischer in Cell Communication and Signaling
    Article Open access 21 March 2024
  17. Identification of microbiogeochemical factors responsible for arsenic release and mobilization, and isolation of heavy metal hyper-tolerant bacterium from irrigation well water: a case study in Rural Bengal

    In Bengal Delta Plain (West Bengal and Bangladesh), shallow aquifer (< 50 m) groundwater is often used in irrigation for paddy cultivation. The...

    Sandipan Barman, Debjani Mandal, ... Abhishek Basu in Environment, Development and Sustainability
    Article 13 January 2023
  18. Reserve mobilization and the role of primary metabolites during the germination and initial seedling growth of rubber tree genotypes

    During seed germination until photoautotrophic establishment, the mobilization of seed-stored reserves represents the main source of carbon...

    Josiane C. de Carvalho, José Francisco de Carvalho Gonçalves, ... Bala Rathinasabapathi in Acta Physiologiae Plantarum
    Article 04 July 2022
  19. Mobilization and Collection of HSCs in Children

    Pediatric hematopoietic stem cell (HSC) products are crucial components of hematopoietic cell transplantation (HCT) in children. This chapter...
    Volker Witt, Herbert Pichler, Norbert Ahrens in The EBMT Handbook
    Chapter Open access 2024
  20. Disorders of Calcium: Physiology

    Calcium (Ca2+) is the most abundant divalent ion in the body. Approximately 1.2–1.3 kg of Ca2+ is present in a 70-kg individual. Of this amount, 99 %...
    Chapter 2023
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