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Bone Fragility Disorders in Childhood and Adolescence
There has been substantial progress in our knowledge over the last two decades about the genetic basis, natural history, and treatment of children... -
Bone and Joint Disorders
Musculoskeletal diseases often cause chronic pain and dysmobility and contribute considerably to the overall burden of disease in older adults. This... -
Metabolic bone disorders and the promise of marine osteoactive compounds
Metabolic bone disorders and associated fragility fractures are major causes of disability and mortality worldwide and place an important financial...
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Altered Caveolin-1 Dynamics Result in Divergent Mineralization Responses in Bone and Vascular Calcification
IntroductionThough vascular smooth muscle cells adopt an osteogenic phenotype during pathological vascular calcification, clinical studies note an...
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The influence of iron on bone metabolism disorders
Iron is a necessary trace element in the human body, and it participates in many physiological processes. Disorders of iron metabolism can cause...
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Different doses of phosphorus, calcium, and vitamin D in premature infants and their effect on bone mineralization: systematic review and meta-analysis
PurposeThis systematic review and meta-analysis aims to assess the impact of different doses of Ca, P, and vitamin D on bone mineralization in...
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Mineralization Impairment Due to Vitamin D Deficiency in Bone Histomorphometry
Vitamin D has an essential nutritional role for the regulation of bone metabolism in the skeleton. Serum 25-hydroxyvitaminD (25OHD), as an indicator... -
Bone Mineralization and Osteoporotic Changes
The nature of continuous bone remodeling can be determined, thanks to the measurement of molecules released by osteoblasts and osteoclasts in the... -
Bone Disease
CKD-MBD refers to spectrum of mineral and bone disorders seen in patients with chronic kidney disease. Renal osteodystrophy refers alterations in... -
Mineral and Bone Disorders in Chronic Kidney Disease
The key players of the CKD–MBD are calcium, phosphorus, PTH, FGF23/Klotho, and the vitamin D hormonal system. The progressive reduction of kidney... -
Bone Material Properties in Bone Diseases Affecting Children
Purpose of ReviewMetabolic and genetic bone disorders affect not only bone mass but often also the bone material, including degree of mineralization,...
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Craniosynostosis in primary metabolic bone disorders: a single-institution experience
PurposeThe incidence of metabolic bone diseases in pediatric neurosurgical patients is rare. We examined our institutional experience of metabolic...
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Genetic Evaluation for Monogenic Disorders of Low Bone Mass and Increased Bone Fragility: What Clinicians Need to Know
Purpose of ReviewThe purpose of this review is to outline the principles of clinical genetic testing and to provide practical guidance to clinicians...
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Bone and Joint Disorders
Musculoskeletal diseases often cause chronic pain and dysmobility and contribute considerably to the overall burden of disease in older adults. This... -
Drug-Related Bone and Soft Tissue Disorders
Numerous pharmacologic agents may adversely affect the musculoskeletal system. Radiographic manifestations of these pathologic effects may often be... -
Bone Remodeling – Clinical Evaluation
The term bone remodeling indicates a series of physiological processes that involve three types of cells, osteoclasts, osteoblasts, and osteocytes,... -
Renal Phosphate Wasting Disorders
The regulation of phosphate handling in the kidney is established in great detail. The balance between the respective rates of glomerular filtration... -
Liver fibrosis is associated with impaired bone mineralization and microstructure in obese individuals with non-alcoholic fatty liver disease
Background and purposeChronic liver diseases are associated with increased bone fracture risk, mostly in end-stage disease and cirrhosis; besides,...
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The effect of caponization on bone homeostasis of crossbred roosters. I. Analysis of tibia bone mineralization, densitometric, osteometric, geometric and biomechanical properties
The presented study focuses on assessing the effect of caponization on the densitometric, osteometric, geometric and biomechanical parameters of...
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Effect of physiotherapy on the promotion of bone mineralization in preterm infants: a randomized controlled trial
Preterm infants have a low level of bone mineralization compared to those born at term. The purpose of the present study was to investigate the...