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Mechanical Ventilation in ARDS
Acute respiratory distress syndrome (ARDS) is a form of hypoxemic respiratory failure, which requires supplemental oxygen delivered by mechanical...
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Early pathophysiology-driven airway pressure release ventilation versus low tidal volume ventilation strategy for patients with moderate-severe ARDS: study protocol for a randomized, multicenter, controlled trial
BackgroundConventional Mechanical ventilation modes used for individuals suffering from acute respiratory distress syndrome have the potential to...
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Fluid Management in COVID-19
Upon initial presentation, most COVID-19 patients are in a stable haemodynamic state and typically do not require intravenous (IV) fluid...
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FX06 to rescue SARS-CoV-2-induced acute respiratory distress syndrome: a randomized clinical trial
BackgroundVascular leakage is a major feature of acute respiratory distress syndrome (ARDS). We aimed to evaluate the efficacy of FX06, a drug under...
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Challenges of anticipation of future decisions in dementia and dementia research
Anticipation of future decisions can be important for individuals at risk for diseases to maintain autonomy over time. For future treatment and care...
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Maternal Characteristics and Outcomes Affected by COVID-19 Pandemic in Indonesia
AimCompare the impact of the intervention on the outcome of pregnancy of patients receiving obstetric care with and non-COVID-19 diagnosis at a...
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A reassessment about included studies and certainty of evidence on a systematic review and meta-analysis of steroid for patients with acute respiratory distress syndrome
We comment on the study by Hirano et al. about the effect of steroids in patients with acute respiratory distress syndrome. It might be necessary to...
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Awake self-proning for COVID-19 non-intubated patients—a single-centered experience
BackgroundCOVID-19 patients with respiratory failure may need intensive care unit (ICU) admission. Prone positioning in mechanically ventilated...
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Nucleic acid-based vaccine platforms against the coronavirus disease 19 (COVID-19)
The coronavirus disease 2019 (COVID-19) pandemic has infected 673,010,496 patients and caused the death of 6,854,959 cases globally until today....
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Prognostic classification based on P/F and PEEP in invasively ventilated ICU patients with hypoxemia—insights from the MARS study
BackgroundOutcome prediction in patients with acute respiratory distress syndrome (ARDS) greatly improves when patients are reclassified based on...
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Compliance with antibiotic therapy guidelines in french paediatric intensive care units: a multicentre observational study
BackgroundBacterial infections (BIs) are widespread in ICUs. The aims of this study were to assess compliance with antibiotic recommendations and...
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Advances in the Evaluation and Treatment of Sepsis and Shock
Over the past few decades, the term “sepsis” has evolved through many definitions, treatment algorithms, and approaches. The institution of the 2016...
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Fluid management for sepsis-induced hypotension in patients with advanced chronic kidney disease: a secondary analysis of the CLOVERS trial
BackgroundEarly fluid management in patients with advanced chronic kidney disease (CKD) and sepsis-induced hypotension is challenging with limited...
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Association of mortality and early tracheostomy in patients with COVID-19: a retrospective analysis
COVID-19 adds to the complexity of optimal timing for tracheostomy. Over the course of this pandemic, and expanded knowledge of the disease, many...
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Noninvasive Mechanical Ventilation in Conventional Respiratory Ward
Acute respiratory failure is a very common cause of in-hospital emergencies (Cabrini et al., Minerva Anestesiol 76(1):71, 2010). As the number of...
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Grundlagen des notfallmedizinischen „Bridgings“ von kritisch kranken Patienten in der Notaufnahme bis zur Intensivstationsverlegung
The decision of the Federal Joint Committee (GBA) on a staged system of emergency structures in hospitals from 2018 stipulates that in hospitals with...
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Noninvasive Ventilation Failure: How to Foresee, Prevent, Diagnose It, and When to Switch to Invasive Mechanical Ventilation
In the past 20 years, noninvasive mechanical ventilation has become the first-line treatment for acute respiratory failure resulting from various...
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Intensive Care Issues in Post-operative Pediatric Liver Transplantation
Pediatric liver transplantation (LT) has become a standard and definitive treatment for end stage liver disease over last few decades. Advances in...