Search
Search Results
-
β-Actin facilitates etoposide-induced p53 nuclear import
As a tumor suppressor, p53 preserves genomic integrity in eukaryotes. However, limited evidence is available for the p53 shuttling between the...
-
Targeting nuclear import and export in hematological malignancies
The transport of proteins across the nuclear membrane is a highly regulated process, essential for the cell function. This transport is actively...
-
Neural Networks for Processing Nuclear Emulsions
AbstractOwing to the development of optical precision and computer technology, the number of experiments based on visual methods for processing data...
-
“South Korea Going Nuclear?”: debates, driving forces, and prospects
The USA ended South Korea’s clandestine quest for an independent nuclear weapons program in the 1970s, resulting in the socialization of nuclear...
-
Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery
The translocase of the outer mitochondrial membrane TOM constitutes the organellar entry gate for nearly all precursor proteins synthesized on...
-
Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ
Manipulation of the subcellular localization of transcription factors by preventing their shuttling via the nuclear pore complex (NPC) emerges as a...
-
Nuclear export of circular RNA
Circular RNAs (circRNAs), which are increasingly being implicated in a variety of functions in normal and cancerous cells
1 –5 , are formed by...
-
New Nuclear Programs: Prospects and Challenges
This chapter aims to shed light on the technical aspects of nuclear production, then briefly elaborate on the historical context of nuclear energy,...
-
Interaction between CD36 and FABP4 modulates adipocyte-induced fatty acid import and metabolism in breast cancer
Adipocytes influence breast cancer behaviour via fatty acid release into the tumour microenvironment. Co-culturing human adipocytes and breast cancer...
-
The Origin of the ROK Nuclear Program
This chapter first illustrates the beginning of ROK Nuclear Program and its limitation. This chapter also explains how and why the political...
-
Nuclear Law: Implementing a Comprehensive Legislation for Newcomers
This Chapter provides a guidance on the fundamental components on nuclear lawmaking and provides basic information for model laws/regulation to deal...
-
Lessons Learnt from the Fukushima Nuclear Accident
Even after 11 years, the Fukushima accident is not completely over yet. Technological challenges for decommissioning of Fukushima are unprecedented....
-
Nuclear Physics in Russia is 100 Years Old
AbstractThe review presents a brief history of the development of nuclear physics since the beginning of the 20th century. The most significant...
-
Nuclear proteins and diabetic retinopathy: a review
Diabetic retinopathy (DR) is an eye disease that causes blindness and vision loss in diabetic. Risk factors for DR include high blood glucose levels...
-
HIV-1 capsids enter the FG phase of nuclear pores like a transport receptor
HIV-1 infection requires nuclear entry of the viral genome. Previous evidence suggests that this entry proceeds through nuclear pore complexes...
-
Dissecting the molecular mechanisms of mitochondrial import and maturation of peroxiredoxins from yeast and mammalian cells
Peroxiredoxins (Prxs) are cysteine-based peroxidases that play a central role in kee** the H 2 O 2 at physiological levels. Eukaryotic cells express...
-
Nuclear Pore Complex-Regulated Transcription and Memory
The nuclear pore complex (NPC) stands as a marvel of cellular architecture that orchestrates the bidirectional traffic of macromolecules between the...
-
Assembly and Disassembly of the Nuclear Pore Complex: A View from the Structural Side
Abstract —Nucleocytoplasmic exchange in the cell occurs through the nuclear pore complexes (NPCs). NPCs are large multiprotein complexes with...
-
Multiphysics FEM Integration Issues – A Case Study in Nuclear Fusion Research Activities
The engineering design phase usually requires the integration of different types of studies and analyses for the definition of the whole system....
-
Protection from α-Synuclein induced dopaminergic neurodegeneration by overexpression of the mitochondrial import receptor TOM20
Dopaminergic neurons of the substantia nigra are selectively vulnerable to mitochondrial dysfunction, which is hypothesized to be an early and...
