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The role of MOTS-c-mediated antioxidant defense in aerobic exercise alleviating diabetic myocardial injury
Myocardial remodeling and dysfunction are commonly observed in type 2 diabetes mellitus (T2DM). Aerobic exercise can partly alleviate...
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Comparative effects of various running exercise modalities on femoral bone quality in rats
BackgroundIt is now well established that physical exercise is an effective preventive method to reduce and treat certain chronic diseases,...
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ASMT determines gut microbiota and increases neurobehavioral adaptability to exercise in female mice
N-acetylserotonin O-methyltransferase (ASMT) is responsible for melatonin biosynthesis. The Asmt gene is located on the X chromosome, and its genetic...
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Optimal dose and type of exercise to improve depressive symptoms in older adults: a systematic review and network meta-analysis
BackgroundDepression is a prevalent issue among older adults, affecting their quality of life and overall well-being. Exercise is an effective means...
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The influence of endurance exercise training on myocardial fibrosis and arrhythmogenesis in a coxsackievirus B3 myocarditis mouse model
Nonischaemic myocardial fibrosis is associated with cardiac dysfunction, malignant arrhythmias and sudden cardiac death. In the absence of a specific...
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Possible role of moderate exercise training in modulating gene expression of adipose tissue remodeling markers in obese male rats
PurposeObesity is a growing public health problem characterized by adipose tissue (AT) dysfunction that is associated with metabolic complications....
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Daytime-restricted feeding enhances running endurance without prior exercise in mice
Physical endurance and energy conservation are essential for survival in the wild. However, it remains unknown whether and how meal timing regulates...
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Interval aerobic/resistance exercise training depresses adrenergic-induced apoptosis of lymphocytes in sedentary males
PurposeAdrenergic stimulation affects lymphocyte autophagy and apoptosis by activating β1-adrenergic receptor (β1-AR) and G protein-coupled receptor...
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A microbiome-dependent gut–brain pathway regulates motivation for exercise
Exercise exerts a wide range of beneficial effects for healthy physiology
1 . However, the mechanisms regulating an individual’s motivation to engage... -
Continuous positive airway pressure acutely increases exercise duration in children with severe therapy-resistant asthma: a randomized crossover trial
BackgroundLower exercise tolerance is an important component of asthma and the possible effects of non-invasive ventilation on exercise capacity in...
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Effects of Exercise and Dietary Modifications on Hidradenitis Suppurativa: A Systematic Review
BackgroundHidradenitis suppurativa affects up to 4% of the population worldwide. Many treatment options exist but these come with a significant...
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New Potential Treatments for Resistant Hypertension
Purpose of ReviewTo provide an update and review approaches to the treatment of resistant hypertension (RH) with a focus on emerging potential...
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Health Risks of Growing Horses Related to Exercise and Parasite Control
In this chapter, health issues related to exercise and parasite control in growing horses are discussed. Concerning problems associated with bone... -
Effects of low-intensity exercise on spontaneously developed knee osteoarthritis in male senescence-accelerated mouse prone 8
BackgroundOsteoarthritis (OA) is a degenerative joint disease associated with aging, which often leads to joint stiffness and disability. Exercise is...
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The efficacy and safety of exercise regimens to mitigate chemotherapy cardiotoxicity: a systematic review and meta-analysis of randomized controlled trials
BackgroundCardiotoxicity is one of the most common adverse events of the chemotherapy. Physical exercise was shown to be cardioprotective. We aim to...
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A Review of Therapeutics for Treatment-Resistant Depression in the Older Adult
One-third of older adults with depression meet criteria for treatment resistance, typically defined as a lack of response to two or more adequate...
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Muscle-to-organ cross-talk mediated by interleukin 6 during exercise: a review
Physical activity is increasingly recommended as a therapeutic approach for various lifestyle-related conditions, including type 2 diabetes,...
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Cellular and Molecular Regulation of Exercise—A Neuronal Perspective
The beneficial effects of exercise on the proper functioning of the body have been firmly established. Multi-systemic metabolic regulation of...
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Similar effects on exercise performance following different respiratory muscle training programs in healthy young men
Both respiratory muscle endurance training (RMET) and inspiratory resistive training (IMT) seem to increase whole-body exercise performance, but...
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Exercise training maintains cardiovascular health: signaling pathways involved and potential therapeutics
Exercise training has been widely recognized as a healthy lifestyle as well as an effective non-drug therapeutic strategy for cardiovascular diseases...