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Showing 61-80 of 1,908 results
  1. Long noncoding RNA H19 regulates the therapeutic efficacy of mesenchymal stem cells in rats with severe acute pancreatitis by sponging miR-138-5p and miR-141-3p

    Background

    Patients with severe acute pancreatitis (SAP), which is characterized by high morbidity and mortality, account for an increasing medical...

    Guodong Song, Jia Zhou, ... Zhenshun Song in Stem Cell Research & Therapy
    Article Open access 25 September 2020
  2. Effects of H19/SAHH/DNMT1 on the oxidative DNA damage related to benzo[a]pyrene exposure

    The mechanisms that long noncoding RNA (lncRNA) H19 binding to S-adenosylhomocysteine hydrolase (SAHH) interacted with DNA methyltransferase 1...

    Ye Fu, Xue**g Li, ... ** Yang in Environmental Science and Pollution Research
    Article 13 September 2022
  3. Long noncoding RNAs as regulators of pediatric acute myeloid leukemia

    Long noncoding RNAs (lncRNAs) are increasingly emerging as regulators across human development and disease, and many have been described in the...

    Sina Neyazi, Michelle Ng, ... Jan-Henning Klusmann in Molecular and Cellular Pediatrics
    Article Open access 20 May 2022
  4. The role of noncoding RNAs in metabolic reprogramming of cancer cells

    Metabolic reprogramming is a well-known feature of cancer that allows malignant cells to alter metabolic reactions and nutrient uptake, thereby...

    Amir Safi, Mohammadreza Saberiyan, ... Reza Ahmadi in Cellular & Molecular Biology Letters
    Article Open access 09 May 2023
  5. Long Intergenic Noncoding RNAs Affect Biological Pathways Underlying Autoimmune and Neurodegenerative Disorders

    Long intergenic noncoding RNAs (lincRNAs) are a class of independently transcribed molecules longer than 200 nucleotides that do not overlap known...

    Patrycja Plewka, Katarzyna Dorota Raczynska in Molecular Neurobiology
    Article Open access 07 July 2022
  6. Function of Long Noncoding RNAs in Glioma Progression and Treatment Based on the Wnt/β-Catenin and PI3K/AKT Signaling Pathways

    Gliomas are a deadly primary malignant tumor of the central nervous system, with glioblastoma (GBM) representing the most aggressive type. The...

    Hanyun Li, Jilan Liu, ... Feng ** in Cellular and Molecular Neurobiology
    Article 25 September 2023
  7. Clinical Utility of Noncoding RNAs as Systemic Biomarkers in Animal Models

    Noncoding RNAs are the RNAs that do not encode for proteins, yet play a vital role in various cellular processes. Compelling cancer research evidence...
    Siuli Shaw, Sartaj Khurana, ... Sudeep Bose in Handbook of Animal Models and its Uses in Cancer Research
    Reference work entry 2023
  8. Diagnostic, prognostic and therapeutic potential of long noncoding RNAs in cancer

    Long noncoding RNAs (lncRNAs) are longer than 200 nucleotides in length and undergo splicing, cap**, polyadenylation, and editing just like mRNA....

    Muhammad Babar Khawar, Syeda Eisha Hamid, ... Nadeem Sheikh in Molecular Biology Reports
    Article 24 January 2022
  9. Altered expression of long noncoding RNA MEG3 in the offspring of gestational diabetes mellitus induces impaired glucose tolerance in adulthood

    Aim

    Gestational diabetes mellitus (GDM) affects a significant number of women worldwide and has been associated with lifelong health consequences for...

    Meng Meng Yang, Juan Wei, ... Qiong Luo in Acta Diabetologica
    Article 09 September 2023
  10. Detection and analysis of long noncoding RNA expression profiles related to epithelial–mesenchymal transition in keloids

    Background

    The role of epithelial-mesenchymal transition (EMT) in the pathogenesis of keloids is currently raising increasing attention. Long...

    Zhixiong Chen, ** Chu, **ghong Xu in BioMedical Engineering OnLine
    Article Open access 11 January 2022
  11. Noncoding RNA-mediated molecular bases of chemotherapy resistance in hepatocellular carcinoma

    Despite the significant progress in decreasing the occurrence and mortality of hepatocellular carcinoma (HCC), it remains a public health issue...

    Qikuan He, Pengyi Guo, ... Gang Chen in Cancer Cell International
    Article Open access 09 August 2022
  12. Role of Curcumin in Regulating Long Noncoding RNA Expression in Cancer

    Phytochemicals are various compounds produced by plants. There is growing evidence on their potential health effects. Some of these compounds are...
    Abolfazl Amini, Parand Khadivar, ... Amirhossein Sahebkar in Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health
    Chapter 2021
  13. A novel imatinib-upregulated long noncoding RNA plays a critical role in inhibition of tumor growth induced by Abl oncogenes

    Background

    Dysregulation of long noncoding RNAs (lncRNAs) has been linked to various human cancers. Bcr-Abl oncogene that results from a reciprocal...

    Yun Ma, Guijie Guo, ... Ji-Long Chen in Molecular Cancer
    Article Open access 03 January 2022
  14. Long noncoding RNA ADAMTS9-AS1 represses ferroptosis of endometrial stromal cells by regulating the miR-6516-5p/GPX4 axis in endometriosis

    Endometriosis (EMs) is one of the most frequent diseases of reproductive-age women and is characterized by the growth of endometrial tissues beyond...

    Yiting Wan, Cancan Gu, ... **g Chen in Scientific Reports
    Article Open access 16 February 2022
  15. The role and possible mechanism of the long noncoding RNA LINC01260 in nonalcoholic fatty liver disease

    Objective

    To investigate the differential expression profile of lncRNAs in the nonalcoholic fatty liver disease (NAFLD) model induced by oleic acid...

    **aoxiao Ge, Tao Sun, ... Sumei Lu in Nutrition & Metabolism
    Article Open access 12 January 2022
  16. Highlighting the role of long non-coding RNA (LncRNA) in multiple myeloma (MM) pathogenesis and response to therapy

    Transcripts longer than 200 nucleotides that are not translated into proteins are known as long non-coding RNAs, or lncRNAs. Now, they are becoming...

    Sulieman Ibraheem Shelash Al-Hawary, Saade Abdalkareem Jasim, ... Ahmed Hussein Zwamel in Medical Oncology
    Article 07 June 2024
  17. Wnt Signaling-Related Long Noncoding RNAs: Critical Mediators of Drug Resistance in Colon Cancer

    Colon cancer is the third largest cancer-related death in the world and is increasing in develo** countries. Several molecular pathways controlled...
    P. Vasudeva Raju, RamaRao Malla in Colon Cancer Diagnosis and Therapy Vol. 3
    Chapter 2022
  18. Long noncoding RNA CRART16 confers 5-FU resistance in colorectal cancer cells by sponging miR-193b-5p

    Background

    The emergence of chemoresistance to 5-fluorouracil (5-FU)-based chemotherapy is the main cause of treatment failure in advanced and...

    **gui Wang, **aoqian Zhang, ... **n Wang in Cancer Cell International
    Article Open access 29 November 2021
  19. A comprehensive understanding of hnRNP A1 role in cancer: new perspectives on binding with noncoding RNA

    The heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is the most abundant and ubiquitously expressed member of the heterogeneous nuclear...

    Luisa Siculella, Laura Giannotti, ... Fabrizio Damiano in Cancer Gene Therapy
    Article 02 December 2022
  20. Regulation of Glial Function by Noncoding RNA in Central Nervous System Disease

    Non-coding RNAs (ncRNAs) are a class of functional RNAs that play critical roles in different diseases. NcRNAs include microRNAs, long ncRNAs, and...

    Ying Bai, Hui Ren, ... Honghong Yao in Neuroscience Bulletin
    Article 26 September 2022
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