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Cell facilitation promotes growth and survival under drug pressure in breast cancer
The interplay of positive and negative interactions between drug-sensitive and resistant cells influences the effectiveness of treatment in...
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Construction of a “nutrition supply–detoxification” coculture consortium for medium-chain-length polyhydroxyalkanoate production with a glucose–xylose mixture
In this study, we constructed a coculture consortium comprising engineered Pseudomonas putida KT2440 and Escherichia coli MG1655. Provision of...
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Inductive Coculture Differentiation of Induced Pluripotent Stem Cells into Cardiomyocytes
Various types of stem cells and nonstem cells have been shown to differentiate or transdifferentiate into cardiomyocytes by way of coculture with...
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Induction of antimicrobial, antioxidant metabolites production by co-cultivation of two red-sea-sponge-associated Aspergillus sp. CO2 and Bacillus sp. COBZ21
The growing spread of infectious diseases has become a potential global health threat to human beings. According to WHO reports, in this study, we...
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Tumor organoid–T-cell coculture systems
T cells are key players in cancer immunotherapy, but strategies to expand tumor-reactive cells and study their interactions with tumor cells at the...
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Repeated dose multi-drug testing using a microfluidic chip-based coculture of human liver and kidney proximal tubules equivalents
A microfluidic multi-organ chip emulates the tissue culture microenvironment, enables interconnection of organ equivalents and overcomes interspecies...
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Induction of Human T Cell Development In Vitro with OP9-DL4-7FS Cells Expressing Human Cytokines
For nearly a generation now, OP9-DL1 and OP9-DL4 cells have provided an efficient and reliable cell system to generate T cells from mouse and human...
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SLPI overexpression in hMSCs could be implicated in the HSC gene expression profile in AML
Acute myeloid leukaemia (AML) is a severe haematological neoplasm that originates from the transformation of haematopoietic stem cells (HSCs) into...
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Comparisons of heavy metals levels in water, sediment and crayfish under rice-crayfish co-culture and pond culture modes with correlation analysis and health risk assessment
With rapid development of the rice-crayfish industry chain and the continuous innovation of crayfish breeding mode, people are increasingly concerned...
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Iron competition triggers antibiotic biosynthesis in Streptomyces coelicolor during coculture with Myxococcus xanthus
Microbial coculture to mimic the ecological habitat has been suggested as an approach to elucidate the effect of microbial interaction on secondary...
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Motor neurons and endothelial cells additively promote development and fusion of human iPSC-derived skeletal myocytes
BackgroundNeurovascular cells have wide-ranging implications on skeletal muscle biology regulating myogenesis, maturation, and regeneration. Although...
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Bivariate genome-wide association study of the growth plasticity of Staphylococcus aureus in coculture with Escherichia coli
AbstractPhenotypic plasticity is the capacity to change the phenotype in response to different environments without alteration of the genotype....
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ADSCs stimulated by resistin promote breast cancer cell malignancy via CXCL5 in a breast cancer coculture model
The tumor microenvironment represents one of the main obstacles in breast cancer treatment owing to the presence of heterogeneous stromal cells, such...
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Influence of different culture media on the antimicrobial activity of Pediococcus pentosaceus ST65ACC against Listeria monocytogenes
Pediococcus pentosaceus ST65ACC is a bacteriocinogenic lactic acid bacteria (LAB) isolated from Brazilian artisanal cheese that is capable of...
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Cellular and molecular mechanisms of highly active mesenchymal stem cells in the treatment of senescence of rhesus monkey ovary
BackgroundRecent studies have shown that umbilical cord mesenchymal stem cells have an anti-aging effect in ovaries, but the cellular and molecular...
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Adipocyte pyroptosis occurs in omental tumor microenvironment and is associated with chemoresistance of ovarian cancer
BackgroundOvarian carcinoma (OC) is a fatal malignancy, with most patients experiencing recurrence and resistance to chemotherapy. In contrast to...
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A Two Bacteriocinogenic Ligilactobacillus Strain Association Inhibits Growth, Adhesion, and Invasion of Salmonella in a Simulated Chicken Gut Environment
In this study, we aimed to develop a protective probiotic coculture to inhibit the growth of Salmonella enterica serovar Typhimurium in the simulated...
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A Compressed Collagen Construct for Studying Endothelial–Smooth Muscle Cell Interaction Under High Shear Stress
The coculture of vascular endothelial cells (ECs) on collagen gels containing smooth muscle cells (SMCs) has been carried out to investigate cellular...
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Blue–green water utilization in rice–fish cultivation towards sustainable food production
Integrated rice–fish culture is a competitive alternative to rice monoculture for environmental sustainability and food productivity. Compared to...
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Tumor-associated macrophages promote resistance of hepatocellular carcinoma cells against sorafenib by activating CXCR2 signaling
BackgroundSorafenib (SOR) is the first line treatment for advanced hepatocellular carcinoma (HCC), but resistance develops frequently....
