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GABAergic motor neurons bias locomotor decision-making in C. elegans
Proper threat-reward decision-making is critical to animal survival. Emerging evidence indicates that the motor system may participate in...
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Effects of Dietary Vitamin D3 on Growth Performance, Immune Status, and Calcium and Phosphorus Metabolism in Litopenaeus vannamei Under Different Salinity Conditions
Vitamin D 3 (VD 3 ) plays a vital role in various physiological processes in addition to its role in regulating the homeostasis of calcium and...
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Pannexin 1 as a driver of inflammation and ischemia–reperfusion injury
Pannexin 1 (Panx1) is a ubiquitously expressed protein forming large conductance channels that are central to many distinct inflammation and injury...
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Cx43 hemichannels and panx1 channels contribute to ethanol-induced astrocyte dysfunction and damage
BackgroundAlcohol, a widely abused drug, significantly diminishes life quality, causing chronic diseases and psychiatric issues, with severe health,...
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Gap junction-mediated cell-to-cell communication in oral development and oral diseases: a concise review of research progress
Homoeostasis depends on the close connection and intimate molecular exchange between extracellular, intracellular and intercellular networks....
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Mechanisms of ATP release in pain: role of pannexin and connexin channels
Pain is a physiological response to bodily damage and serves as a warning of potential threat. Pain can also transform from an acute response to...
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Analysis and Visualization of Single-Cell Sequencing Data with Scanpy and MetaCell: A Tutorial
The emergence and development of single-cell RNA sequencing (scRNA-seq) techniques enable researchers to perform large-scale analysis of the...
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NMDAR-mediated modulation of gap junction circuit regulates olfactory learning in C. elegans
Modulation of gap junction-mediated electrical synapses is a common form of neural plasticity. However, the behavioral consequence of the modulation...
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Transcriptome analysis provides genome annotation and expression profiles in the central nervous system of Lymnaea stagnalis at different ages
BackgroundThe pond snail, Lymnaea stagnalis ( L. stagnalis ), has served as a valuable model organism for neurobiology studies due to its simple and...
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ATP signaling in the integrative neural center of Aplysia californica
ATP and its ionotropic P2X receptors are components of the most ancient signaling system. However, little is known about the distribution and...
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ATP transporters in the joints
Extracellular adenosine triphosphate (ATP) plays a central role in a wide variety of joint diseases. ATP is generated intracellularly, and the...
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Pannexin 3 channels in health and disease
Pannexin 3 (PANX3) is a member of the pannexin family of single membrane channel-forming glycoproteins. Originally thought to have a limited...
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Molecular and circuit mechanisms underlying avoidance of rapid cooling stimuli in C. elegans
The mechanisms by which animals respond to rapid changes in temperature are largely unknown. Here, we found that polymodal ASH sensory neurons...
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Gap junction gene innexin3 being highly expressed in the nervous system and embryonic stage of the mud crab Scylla paramamosain
Innexin proteins are a class of transmembrane proteins existing in invertebrates and they have diverse biological functions. The innexin protein...
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Single-cell expression profile of Drosophila ovarian follicle stem cells illuminates spatial differentiation in the germarium
BackgroundHow stem cell populations are organized and regulated within adult tissues is important for understanding cancer origins and for develo**...
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Wrap** glia regulates neuronal signaling speed and precision in the peripheral nervous system of Drosophila
The functionality of the nervous system requires transmission of information along axons with high speed and precision. Conductance velocity depends...
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Pannexin 1 channels and ATP release in epilepsy: two sides of the same coin
Purinergic signaling mediated by ATP and its metabolites contributes to various brain physiological processes as well as to several pathological...
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Taste transduction and channel synapses in taste buds
The variety of taste sensations, including sweet, umami, bitter, sour, and salty, arises from diverse taste cells, each of which expresses specific...
