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Cell-specific localization of β-synuclein in the mouse retina
β-synuclein, a member of the synuclein family, is frequently co-expressed with α-synuclein in the neural system, where it serves to inhibit abnormal...
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Assessing migraine patients with multifocal pupillographic objective perimetry
BackgroundTo establish the effects of stimulating intrinsically-photosensitive retinal ganglion cells (ipRGCs) on migraine severity, and to determine...
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Diversity of intrinsically photosensitive retinal ganglion cells: circuits and functions
The melanopsin-expressing, intrinsically photosensitive retinal ganglion cells (ipRGCs) are a relatively recently discovered class of atypical...
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Blue light blind-spot stimulation upregulates b-wave and pattern ERG activity in myopes
Upregulation of retinal dopaminergic activity may be a target treatment for myopia progression. This study aimed to explore the viability of inducing...
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Melanopsin-mediated optical entrainment regulates circadian rhythms in vertebrates
Melanopsin (OPN4) is a light-sensitive protein that plays a vital role in the regulation of circadian rhythms and other nonvisual functions. Current...
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Variable abnormality of the melanopsin-derived portion of the pupillary light reflex (PLR) in patients with Parkinson’s disease (PD) and parkinsonism features
ObjectivesAscertain and quantify abnormality of the melanopsin-derived portion of the pupillary light reflex (PLR) in patients with Parkinson’s...
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A Comprehensive Overview of the Neural Mechanisms of Light Therapy
Light is a powerful environmental factor influencing diverse brain functions. Clinical evidence supports the beneficial effect of light therapy on...
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Non-visual Effects Driven Fatigue Level Recognition Method for Enclosed Space Workers
With the rapid development of underground space and manned tourist deep diver careers, it is of great research value to enhance the comfort and task...
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Effects of different light incident angles via a head-mounted device on the magnitude of nocturnal melatonin suppression in healthy young subjects
Bright light is a primary zeitgeber (synchronizer) for the central circadian pacemaker in humans. Recently, head-mounted devices for light therapy...
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Retinal innervation tunes circuits that drive nonphotic entrainment to food
Daily changes in light and food availability are major time cues that influence circadian timing
1 . However, little is known about the circuits that...
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Review on age-related differences in non-visual effects of light: melatonin suppression, circadian phase shift and pupillary light reflex in children to older adults
Physiological effects of light exposure in humans are diverse. Among them, the circadian rhythm phase shift effect in order to maintain a 24-h cycle...
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Circadian-independent light regulation of mammalian metabolism
The daily light–dark cycle is a key zeitgeber (time cue) for entraining an organism’s biological clock, whereby light sensing by retinal...
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Differences in the pupillary responses to evening light between children and adolescents
BackgroundIn the mammalian retina, intrinsically-photosensitive retinal ganglion cells (ipRGC) detect light and integrate signals from rods and cones...
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Methods to Identify Rat and Mouse Retinal Ganglion Cells in Retinal Flat-Mounts
The identification of distinct retinal ganglion cell (RGC) populations in flat-mounted retinas is key to investigating pathological or...
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Blue-light effects on saccadic eye movements and attentional disengagement
People are constantly exposed to high-energy blue light as they spend considerable amounts of time reading and browsing materials on electronic...
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Dopamine modulates the retinal clock through melanopsin-dependent regulation of cholinergic waves during development
BackgroundThe mammalian retina contains an autonomous circadian clock that controls various aspects of retinal physiology and function, including...
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Light Therapy in Chronic Migraine
Purpose of ReviewThis review assesses the effectiveness and safety of light therapy, particularly green light therapy, as an emerging...
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Light modulates task-dependent thalamo-cortical connectivity during an auditory attentional task
Exposure to blue wavelength light stimulates alertness and performance by modulating a widespread set of task-dependent cortical and subcortical...
