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1. Is Nrf2 Behind Endogenous Neuroprotection of the Hippocampal CA2-4,DG Region?

   The transcription factor nuclear factor-erythroid 2-related factor 2 (Nrf2) is the master regulator of genes known to be involved in antioxidant, and...

   Anita Lewczuk, Barbara Zablocka, Malgorzata Beresewicz-Haller in Molecular Neurobiology

   Article Open access 22 December 2022
   

2. Synergistic neuroprotection by phytocompounds of Bacopa monnieri in scopolamine-induced Alzheimer’s disease mice model

   Background

   Millions of people around the globe are affected by Alzheimer’s disease (AD). This crippling condition has no treatment despite intensive...

   Shehla Shoukat, Muhammad Amir Zia, ... Ghulam Muhammad Ali in Molecular Biology Reports

   Article 03 August 2023
   

3. Valsartan: An Angiotensin Receptor Blocker Modulates BDNF Expression and Provides Neuroprotection Against Cerebral Ischemic Reperfusion Injury

   AT1 receptor blockers (ARBs) are commonly used drugs to treat cardiovascular disease and hypertension, but research on their impact on brain...

   Mubashshir Ali, Heena Tabassum, ... Suhel Parvez in Molecular Neurobiology

   Article 25 May 2024
   

4. Neuroprotection and axon regeneration by novel low-molecular-weight compounds through the modification of DOCK3 conformation

   Dedicator of cytokinesis 3 (DOCK3) is an atypical member of the guanine nucleotide exchange factors (GEFs) and plays important roles in neurite...

   Kazuhiko Namekata, Naoki Tsuji, ... Takayuki Harada in Cell Death Discovery

   Article Open access 15 May 2023
   

5. Intravitreal MPTP drives retinal ganglion cell loss with oral nicotinamide treatment providing robust neuroprotection

   Neurodegenerative diseases have common underlying pathological mechanisms including progressive neuronal dysfunction, axonal and dendritic...

   Anne Rombaut, Danica Jovancevic, ... Pete A. Williams in Acta Neuropathologica Communications

   Article Open access 21 May 2024
   

6. Human Wharton’s Jelly Mesenchymal Stem Cell Secretome Modifies the Processes of Neuroprotection and Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium at Transcriptional Level

   Background

   Retinal pigment epithelium (RPE) cells are potential targets for treating retinal detachment (RD) and proliferative vitreoretinopathy...

   M. Hossein Nowroozzadeh, Shiva Ghazanfari, Fatemeh Sanie-Jahromi in Molecular Biology Reports

   Article 22 May 2023
   

7. Biomimetic single Al-OH site with high acetylcholinesterase-like activity and self-defense ability for neuroprotection

   Neurotoxicity of organophosphate compounds (OPs) can catastrophically cause nervous system injury by inhibiting acetylcholinesterase (AChE)...

   Weiqing Xu, **aoli Cai, ... Chengzhou Zhu in Nature Communications

   Article Open access 28 September 2023
   

8. Pharmacological Modulation of Endogenous Neuroprotection after Experimental Prenatal Hypoxia

   Abstract —Prenatal hypoxia (PH) causes pathological changes in the brain and can lead to irreversible long-term disorders of brain development and the...

   I. F. Belenichev, E. G. Aliyeva, ... N. O. Gorchakova in Neurochemical Journal

   Article 18 March 2022
   

9. Developments in Neuroprotection for HIV-Associated Neurocognitive Disorders (HAND)

   Purpose of Review

   Reducing the risk of HIV-associated neurocognitive disorders (HAND) is an elusive treatment goal for people living with HIV....

   Dennis L. Kolson in Current HIV/AIDS Reports

   Article Open access 22 July 2022
   

10. Integrated inflammatory signaling landscape response after delivering Elovanoid free-fatty-acid precursors leading to experimental stroke neuroprotection

    Despite efforts to identify modulatory neuroprotective mechanisms of damaging ischemic stroke cascade signaling, a void remains on an effective...

    Madigan M. Reid, Ludmila Belayev, ... Nicolas G. Bazan in Scientific Reports

    Article Open access 22 September 2023
    

11. VCAM-1⁺ hUC-MSCs Exert Considerable Neuroprotection Against Cerebral Infarction in Rats by Suppression of NLRP3-Induced Pyroptosis

    Mesenchymal stem/stromal cells (MSCs) are spindle-like heterogeneous cell populations with advantageous bidirectional immunomodulatory and...

    **ao Zhang, **aoyu Sang, ... ** Wang in Neurochemical Research

    Article 19 June 2023
    

12. Irisin exhibits neuroprotection by preventing mitochondrial damage in Parkinson’s disease

    Exercise has been proposed as an effective non-pharmacological management for Parkinson’s disease (PD) patients. Irisin, a recently identified...

    ** Zhang, Sutong Xu, ... Siguang Li in npj Parkinson's Disease

    Article Open access 31 January 2023
    

13. cPKCγ-Modulated Autophagy Contributes to Ischemic Preconditioning–Induced Neuroprotection in Mice with Ischemic Stroke via mTOR-ULK1 Pathway

    Neuron-specific conventional protein kinase C (cPKC)γ mediates cerebral hypoxic preconditioning (HPC). In parallel, autophagy plays a prosurvival...

    Ying Zhang, Longhui Ma, ... Xunming Ji in Translational Stroke Research

    Article 10 October 2022
    

14. A Narrative Review on Axonal Neuroprotection in Multiple Sclerosis

    Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) resulting in demyelination and neurodegeneration. The...

    Nicolas Collongues, Guillaume Becker, ... Ayikoé Guy Mensah-Nyagan in Neurology and Therapy

    Article Open access 24 May 2022
    

15. Optic Nerve Crush Injury in Rodents to Study Retinal Ganglion Cell Neuroprotection and Regeneration

    Optic nerve crush injury is a useful model for studying the response of central nervous system neurons (CNS) to injury. A particular focus of this...

    Zubair Ahmed in Retinal Ganglion Cells

    Protocol 2023
    

16. Karan**: a potential furanoflavonoid for neuroprotection

    Phytochemicals are widely known for the pharmacological effects in treating various human conditions and in recent years, new compounds are being...

    Charles Gnanaraj, Mogana Govendan, ... Wing-Hin Lee in Phytochemistry Reviews

    Article 17 February 2024
    

17. Hesperidin Supplementation During Alternate Day Fasting Provides Synergistic Effect in Conferring Neuroprotection to Aging Rats

    Alternate day fasting (ADF) is a beneficial dietary intervention that reduces age- associated complications. Hesperidin is a potential antioxidant...

    Sukanya Bhoumik, Rashmi Kesherwani, Syed Ibrahim Rizvi in Indian Journal of Clinical Biochemistry

    Article 04 April 2024
    

18. Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection

    Insulin-like growth factor I (IGF-1) is a neurotrophic factor and is the ligand for insulin-like growth factor 1 receptor (IGF-1R). Reduced...

    Ammaji Rajala, Kenneth Teel, ... Raju V. S. Rajala in Cell Death & Disease

    Article Open access 15 July 2022
    

19. Suppression of Chronic Unpredictable Stress-Persuaded Increased Monoamine Oxidase Activity by Taurine Promotes Significant Neuroprotection in Zebrafish Brain

    Neuropsychiatric upshots following chronic exposure to unpredictable adverse stressors have been well documented in the literature. Considering the...

    Lilesh Kumar Pradhan, Pradyumna Kumar Sahoo, ... Saroj Kumar Das in Neurochemical Research

    Article 24 August 2022
    

20. A systematic review of immune-based interventions for perinatal neuroprotection: closing the gap between animal studies and human trials

    Background

    Perinatal infection/inflammation is associated with a high risk for neurological injury and neurodevelopmental impairment after birth....

    Sharmony B. Kelly, Nhi T. Tran, ... Robert Galinsky in Journal of Neuroinflammation

    Article Open access 20 October 2023